Prevalence, Distribution, and Histopathological Features of Malignant Tumors Reported at Tertiary Level in Afghanistan: A 3-Year Study

• Published in: Cancer Management and Research
• Main Authors: Malakzai,Haider Ali, Haidary,Ahmed Maseh, Gulzar,Saleema, Haidari,Mujtaba, Ibrahimkhil,Abdul Sami, Saadaat,Ramin, Hakimi,Ahmadullah, Sadat Hofiani,Sayed Murtaza, Rahmani,Soma, Abdul-Ghafar,Jamshid
• Format: Article in Journal/Newspaper
• Language: English
• Published: Dove Press 2022
• Subjects: Cancer Management and Research; sami
• Online Access: https://www.dovepress.com/prevalence-distribution-and-histopathological-features-of-malignant-tu-peer-reviewed-fulltext-article-CMAR

Haider Ali Malakzai,1 Ahmed Maseh Haidary,1 Saleema Gulzar,2 Mujtaba Haidari,1 Abdul Sami Ibrahimkhil,3 Ramin Saadaat,1 Ahmadullah Hakimi,1 Sayed Murtaza Sadat Hofiani,4 Soma Rahmani,5 Jamshid Abdul-Ghafar1 1Department of Pathology and Clinical Laboratory, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan; 2School of Nursing and Midwifery, Aga Khan University (AKU), Karachi, Pakistan; 3Central Public Health Laboratories (CPHL), Kabul, Afghanistan; 4Department of Academics and Research, Postgraduate Medical Education (PGME), French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan; 5World Health Organization (WHO), United Nations Office for the Coordination of Humanitarian and Economic Assistance Programmes Relating to Afghanistan (UNOCA) Compound, Kabul, AfghanistanCorrespondence: Jamshid Abdul-Ghafar, Tel [phone], Email [e-mail]: Cancer is one of the leading causes of mortality and morbidity, and therefore, tremendous research work is continuously being done around the world with consideration of etiopathogenesis as well as identification of therapeutic targets. Decades of continuous war in Afghanistan has left the medical infrastructure of the country in a miserable situation. There is a serious deficiency in research work in the fields of pathology and oncology at the moment with minimal data available to elaborate about the demographic characteristics of various malignant disorders in the country, which would be indispensable to pave the way for further research and development.Patients and Methods: A descriptive cross-sectional study was conducted to describe the prevalence, distribution, and important histopathological features of malignant tumors reported at tertiary level in Afghanistan.Results: Out of 2328 consecutive cases of solid malignant tumors included in our study, 93.8% were primary and 6.2% were metastatic. Breast was the most common site of origin for primary malignancy (29.5%) in females; however, in males, esophagus ...