The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
Helle Jørgensen,1– 3 Erzsébet Horváth-Puhó,2 Kristina Laugesen,2 Sigrid K Braekkan,1,3 John-Bjarne Hansen,1,3 Henrik Toft Sørensen2 1Thrombosis Research Center (TREC), Department of Clinical Medicine, UiT, The Arctic University of Norway, Tromsø, Norway; 2Department of Clinical Epidemiology,...
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ftdovepress:oai:dovepress.com/74529 2023-05-15T17:39:24+02:00 The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension Jørgensen,Helle Horváth-Puhó,Erzsébet Laugesen,Kristina Braekkan,Sigrid K Hansen,John-Bjarne Sørensen,Henrik Toft 2022-04-14 text/html https://www.dovepress.com/the-interaction-between-venous-thromboembolism-and-socioeconomic-statu-peer-reviewed-fulltext-article-CLEP en eng Dove Press info:eu-repo/semantics/altIdentifier/doi/10.2147/CLEP.S361840 https://www.dovepress.com/the-interaction-between-venous-thromboembolism-and-socioeconomic-statu-peer-reviewed-fulltext-article-CLEP info:eu-repo/semantics/openAccess Clinical Epidemiology Original Research info:eu-repo/semantics/article 2022 ftdovepress https://doi.org/10.2147/CLEP.S361840 2022-12-27T23:29:04Z Helle Jørgensen,1– 3 Erzsébet Horváth-Puhó,2 Kristina Laugesen,2 Sigrid K Braekkan,1,3 John-Bjarne Hansen,1,3 Henrik Toft Sørensen2 1Thrombosis Research Center (TREC), Department of Clinical Medicine, UiT, The Arctic University of Norway, Tromsø, Norway; 2Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark; 3Division of Internal Medicine, University Hospital of North Norway, Tromsø, NorwayCorrespondence: Helle Jørgensen, Email helle.jorgensen@uit.noBackground: Venous thromboembolism (VTE) is associated with increased risk of disability pension. How socioeconomic status (SES) impacts the risk of disability pension after a VTE is unknown. The aim of this nationwide population based cohort study to investigate the interaction between SES and incident VTE on the risk of subsequent disability pension.Methods: Using Danish national medical and administrative databases, we established a nationwide cohort of 41,781 individuals aged 25– 65 years with incident VTE during 1995– 2016 and a comparison cohort (n=208,905) from the general population matched on year of birth, sex, and calendar year of VTE. We computed incidence rates (IRs) as the number of disability pension events per 1000 person-years at risk and measured the interaction between VTE and levels of SES (high, medium, low) on an additive scale by calculating interaction contrasts (difference in IR difference).Results: Among individuals with high SES, the disability pension IR per 1000 person-years was 5.4 (95% CI: 4.8– 6.1) in the VTE cohort and 1.6 (95% CI: 1.5– 1.7) in the comparison cohort (IR difference 3.8). The corresponding disability pension IR in individuals with low SES was 55.1 (95% CI: 52.1– 58.1) in the VTE cohort and 26.1 (95% CI: 25.1– 27.1) in the comparison cohort (IR difference 24.0). An interaction contrast of 25.1 indicated that interaction accounted for 45.6% (25.1/55.1) of the disability pension IR in individuals with VTE and low ... Article in Journal/Newspaper North Norway Arctic University of Norway UiT The Arctic University of Norway Dove Medical Press Arctic Norway Sigrid ENVELOPE(-64.233,-64.233,-64.250,-64.250) Helle ENVELOPE(14.664,14.664,68.243,68.243) Clinical Epidemiology Volume 14 489 500 |
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Clinical Epidemiology Jørgensen,Helle Horváth-Puhó,Erzsébet Laugesen,Kristina Braekkan,Sigrid K Hansen,John-Bjarne Sørensen,Henrik Toft The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension |
topic_facet |
Clinical Epidemiology |
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Helle Jørgensen,1– 3 Erzsébet Horváth-Puhó,2 Kristina Laugesen,2 Sigrid K Braekkan,1,3 John-Bjarne Hansen,1,3 Henrik Toft Sørensen2 1Thrombosis Research Center (TREC), Department of Clinical Medicine, UiT, The Arctic University of Norway, Tromsø, Norway; 2Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark; 3Division of Internal Medicine, University Hospital of North Norway, Tromsø, NorwayCorrespondence: Helle Jørgensen, Email helle.jorgensen@uit.noBackground: Venous thromboembolism (VTE) is associated with increased risk of disability pension. How socioeconomic status (SES) impacts the risk of disability pension after a VTE is unknown. The aim of this nationwide population based cohort study to investigate the interaction between SES and incident VTE on the risk of subsequent disability pension.Methods: Using Danish national medical and administrative databases, we established a nationwide cohort of 41,781 individuals aged 25– 65 years with incident VTE during 1995– 2016 and a comparison cohort (n=208,905) from the general population matched on year of birth, sex, and calendar year of VTE. We computed incidence rates (IRs) as the number of disability pension events per 1000 person-years at risk and measured the interaction between VTE and levels of SES (high, medium, low) on an additive scale by calculating interaction contrasts (difference in IR difference).Results: Among individuals with high SES, the disability pension IR per 1000 person-years was 5.4 (95% CI: 4.8– 6.1) in the VTE cohort and 1.6 (95% CI: 1.5– 1.7) in the comparison cohort (IR difference 3.8). The corresponding disability pension IR in individuals with low SES was 55.1 (95% CI: 52.1– 58.1) in the VTE cohort and 26.1 (95% CI: 25.1– 27.1) in the comparison cohort (IR difference 24.0). An interaction contrast of 25.1 indicated that interaction accounted for 45.6% (25.1/55.1) of the disability pension IR in individuals with VTE and low ... |
format |
Article in Journal/Newspaper |
author |
Jørgensen,Helle Horváth-Puhó,Erzsébet Laugesen,Kristina Braekkan,Sigrid K Hansen,John-Bjarne Sørensen,Henrik Toft |
author_facet |
Jørgensen,Helle Horváth-Puhó,Erzsébet Laugesen,Kristina Braekkan,Sigrid K Hansen,John-Bjarne Sørensen,Henrik Toft |
author_sort |
Jørgensen,Helle |
title |
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension |
title_short |
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension |
title_full |
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension |
title_fullStr |
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension |
title_full_unstemmed |
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension |
title_sort |
interaction between venous thromboembolism and socioeconomic status on the risk of disability pension |
publisher |
Dove Press |
publishDate |
2022 |
url |
https://www.dovepress.com/the-interaction-between-venous-thromboembolism-and-socioeconomic-statu-peer-reviewed-fulltext-article-CLEP |
long_lat |
ENVELOPE(-64.233,-64.233,-64.250,-64.250) ENVELOPE(14.664,14.664,68.243,68.243) |
geographic |
Arctic Norway Sigrid Helle |
geographic_facet |
Arctic Norway Sigrid Helle |
genre |
North Norway Arctic University of Norway UiT The Arctic University of Norway |
genre_facet |
North Norway Arctic University of Norway UiT The Arctic University of Norway |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.2147/CLEP.S361840 https://www.dovepress.com/the-interaction-between-venous-thromboembolism-and-socioeconomic-statu-peer-reviewed-fulltext-article-CLEP |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.2147/CLEP.S361840 |
container_title |
Clinical Epidemiology |
container_volume |
Volume 14 |
container_start_page |
489 |
op_container_end_page |
500 |
_version_ |
1766140166149242880 |