Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study
Ahmad H Alghadir,1 Sami A Gabr,1,2 Muaz Al-Ghadir3 1Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia; 2Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 3Department of Orthopedics, King Fahad Med...
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ftdovepress:oai:dovepress.com/66717 2023-05-15T18:11:50+02:00 Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study Alghadir,Ahmad H Gabr,Sami A Al-Ghadir,Muaz 2021-07-07 text/html https://www.dovepress.com/oxidative-stress-and-musculoskeletal-pain-in-university-students-with--peer-reviewed-fulltext-article-JPR en eng Dove Press info:eu-repo/semantics/altIdentifier/doi/10.2147/JPR.S310022 https://www.dovepress.com/oxidative-stress-and-musculoskeletal-pain-in-university-students-with--peer-reviewed-fulltext-article-JPR info:eu-repo/semantics/openAccess Journal of Pain Research Original Research info:eu-repo/semantics/article 2021 ftdovepress https://doi.org/10.2147/JPR.S310022 2022-12-27T23:14:40Z Ahmad H Alghadir,1 Sami A Gabr,1,2 Muaz Al-Ghadir3 1Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia; 2Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 3Department of Orthopedics, King Fahad Medical City, Riyadh, Kingdom of Saudi ArabiaCorrespondence: Sami A GabrRehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi ArabiaTel +966 562060018Fax +966 14698541Email dr.samigabr@gmail.comObjective: The current case–control study aimed to evaluate generalized joint hypermobility (GJH) and its association with pain intensity, cellular oxidative stress, and collagen-associated disorders in university students aged 18– 25 years old.Background: Joint hypermobility has been recognized in healthy subjects and people who are carriers of cellular disorders in connective tissues. Cellular tissue oxidative stress and collagen-associated disorders were shown to be associated with joint hypermobility (JH).Materials and Methods: A total of 300 university students aged 18– 25 years were randomly invited from different medical and science faculties in Mansoura university, Mansoura, Egypt to participate in this case–control study. Only 280 university students who had no exclusion criteria like chronic health problems, physical disability, musculoskeletal disorders, and body mass index (BMI) of ≥ 25 underwent an initial clinical interview and Beighton scoring as measures of GJH. Pain intensity, physical activity, oxidative stress parameters; TAC, TOC, OSI, and collagen-associated parameters; cellular prolidase activity and hydroxyproline were evaluated by using a prevalidated questionnaire, colorimetric, and immunoassay techniques.Results: GJH was significantly reported in 57.1% of the study population, and most of them are females. Compared to men, females with GJH showed poor physical activity, lower TAC, and significantly higher levels of TOC, OSI, cellular ... Article in Journal/Newspaper sami Dove Medical Press Tac ENVELOPE(-59.517,-59.517,-62.500,-62.500) Journal of Pain Research Volume 14 2029 2037 |
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Journal of Pain Research Alghadir,Ahmad H Gabr,Sami A Al-Ghadir,Muaz Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study |
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Journal of Pain Research |
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Ahmad H Alghadir,1 Sami A Gabr,1,2 Muaz Al-Ghadir3 1Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia; 2Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 3Department of Orthopedics, King Fahad Medical City, Riyadh, Kingdom of Saudi ArabiaCorrespondence: Sami A GabrRehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi ArabiaTel +966 562060018Fax +966 14698541Email dr.samigabr@gmail.comObjective: The current case–control study aimed to evaluate generalized joint hypermobility (GJH) and its association with pain intensity, cellular oxidative stress, and collagen-associated disorders in university students aged 18– 25 years old.Background: Joint hypermobility has been recognized in healthy subjects and people who are carriers of cellular disorders in connective tissues. Cellular tissue oxidative stress and collagen-associated disorders were shown to be associated with joint hypermobility (JH).Materials and Methods: A total of 300 university students aged 18– 25 years were randomly invited from different medical and science faculties in Mansoura university, Mansoura, Egypt to participate in this case–control study. Only 280 university students who had no exclusion criteria like chronic health problems, physical disability, musculoskeletal disorders, and body mass index (BMI) of ≥ 25 underwent an initial clinical interview and Beighton scoring as measures of GJH. Pain intensity, physical activity, oxidative stress parameters; TAC, TOC, OSI, and collagen-associated parameters; cellular prolidase activity and hydroxyproline were evaluated by using a prevalidated questionnaire, colorimetric, and immunoassay techniques.Results: GJH was significantly reported in 57.1% of the study population, and most of them are females. Compared to men, females with GJH showed poor physical activity, lower TAC, and significantly higher levels of TOC, OSI, cellular ... |
format |
Article in Journal/Newspaper |
author |
Alghadir,Ahmad H Gabr,Sami A Al-Ghadir,Muaz |
author_facet |
Alghadir,Ahmad H Gabr,Sami A Al-Ghadir,Muaz |
author_sort |
Alghadir,Ahmad H |
title |
Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study |
title_short |
Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study |
title_full |
Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study |
title_fullStr |
Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study |
title_full_unstemmed |
Oxidative Stress and Musculoskeletal Pain in University Students with Generalized Joint Hypermobility: A Case–Control Study |
title_sort |
oxidative stress and musculoskeletal pain in university students with generalized joint hypermobility: a case–control study |
publisher |
Dove Press |
publishDate |
2021 |
url |
https://www.dovepress.com/oxidative-stress-and-musculoskeletal-pain-in-university-students-with--peer-reviewed-fulltext-article-JPR |
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ENVELOPE(-59.517,-59.517,-62.500,-62.500) |
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sami |
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info:eu-repo/semantics/altIdentifier/doi/10.2147/JPR.S310022 https://www.dovepress.com/oxidative-stress-and-musculoskeletal-pain-in-university-students-with--peer-reviewed-fulltext-article-JPR |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.2147/JPR.S310022 |
container_title |
Journal of Pain Research |
container_volume |
Volume 14 |
container_start_page |
2029 |
op_container_end_page |
2037 |
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1766184457938665472 |