Cytotoxic Potential, Metabolic Profiling, and Liposomes of Coscinoderma sp. Crude Extract Supported by in silico Analysis

• Published in: International Journal of Nanomedicine
• Main Authors: Musa,Arafa, Elmaidomy,Abeer H, Sayed,Ahmed M, Alzarea,Sami I, Al-Sanea,Mohammad M, Mostafa,Ehab M, Hendawy,Omina Magdy, Abdelgawad,Mohamed A, Youssif,Khayrya A, Refaat,Hesham, Alaaeldin,Eman, Abdelmohsen,Usama Ramadan
• Format: Article in Journal/Newspaper
• Language: English
• Published: Dove Press 2021
• Subjects: International Journal of Nanomedicine; Musa; sami
• Online Access: https://www.dovepress.com/cytotoxic-potential-metabolic-profiling-and-liposomes-of-coscinoderma--peer-reviewed-fulltext-article-IJN

Arafa Musa,1,2 Abeer H Elmaidomy,3 Ahmed M Sayed,4 Sami I Alzarea,5 Mohammad M Al-Sanea,6 Ehab M Mostafa,1,2 Omina Magdy Hendawy,5,7 Mohamed A Abdelgawad,6 Khayrya A Youssif,8 Hesham Refaat,9 Eman Alaaeldin,10,11 Usama Ramadan Abdelmohsen12,13 1Department of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, 72341, Saudi Arabia; 2Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, 11371, Egypt; 3Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62511, Egypt; 4Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef, 62513, Egypt; 5Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia; 6Pharmaceutical Chemistry Department, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia; 7Department of Clinical Pharmacology, Faculty of Medicine, Beni-Suef University, Beni-Suef, 62513, Egypt; 8Department of Pharmacognosy, Faculty of Pharmacy, Modern University for Technology and Information, Cairo, Egypt; 9Department of Pharmaceutics, Faculty of Pharmacy, Deraya University, 7 Universities Zone, New Minia, 61111, Egypt; 10Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; 11Department of Clinical Pharmacy, Faculty of Pharmacy, Deraya University, 7 Universities Zone, New Minia, 61111, Egypt; 12Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; 13Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, 7 Universities Zone, New Minia, 61111, EgyptCorrespondence: Eman AlaaeldinDepartment of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, 61519, EgyptEmail [e-mail]: Sponge-Coscinoderma sp. (Family: Spongiidae) is a coastal sponge that possesses a broad variety of natural-products. However, the exact chemical constituents and cytotoxic activity of the extract are still undefinable.Methodology: In the present study, the metabolomic profiling of ...