Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression
Ahmad H Alghadir ,1 Sami A Gabr 1 Rehabilitation Research Chair (RRC), College of Applied Medical Sciences (CAMS), King Saud University, Riyadh, Kingdom of Saudi ArabiaCorrespondence: Sami A GabrRehabilitation Research Chair (RRC), College of Applied Medical Sciences (CAMS), King Saud University, P....
Published in: | Clinical Interventions in Aging |
---|---|
Main Authors: | , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Dove Press
2020
|
Subjects: | |
Online Access: | https://www.dovepress.com/hormonal-function-responses-to-moderate-aerobic-exercise-in-older-adul-peer-reviewed-fulltext-article-CIA |
id |
ftdovepress:oai:dovepress.com/55867 |
---|---|
record_format |
openpolar |
spelling |
ftdovepress:oai:dovepress.com/55867 2023-05-15T18:11:58+02:00 Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression Alghadir,Ahmad H Gabr,Sami A 2020-08-03 text/html https://www.dovepress.com/hormonal-function-responses-to-moderate-aerobic-exercise-in-older-adul-peer-reviewed-fulltext-article-CIA en eng Dove Press info:eu-repo/semantics/altIdentifier/doi/10.2147/CIA.S259422 https://www.dovepress.com/hormonal-function-responses-to-moderate-aerobic-exercise-in-older-adul-peer-reviewed-fulltext-article-CIA info:eu-repo/semantics/openAccess Clinical Interventions in Aging Original Research info:eu-repo/semantics/article 2020 ftdovepress https://doi.org/10.2147/CIA.S259422 2022-12-27T22:54:36Z Ahmad H Alghadir ,1 Sami A Gabr 1 Rehabilitation Research Chair (RRC), College of Applied Medical Sciences (CAMS), King Saud University, Riyadh, Kingdom of Saudi ArabiaCorrespondence: Sami A GabrRehabilitation Research Chair (RRC), College of Applied Medical Sciences (CAMS), King Saud University, P.O. Box 10219, Riyadh 11433, Kingdom of Saudi ArabiaTel +966 562060018Fax +966 14698541Email dr.samigabr@gmail.comBackground: Poor daily life physical activities among older people were related to depressive mood especially memory loss. In addition to that, the change in physical ability is significantly associated with the score of depression among older age.Objective: The present study aimed to evaluate the effects of a supervised aerobic training program with moderate intensity for 12 weeks on mood profiles and hormonal levels of the hypothalamus-pituitary-adrenal axis (HPA axis) of older adults.Methods: A total of 80 individuals of both gender (90 males, 110 females) of ages ranged between 65 and 95 years were recruited for this study. Based upon the profile of mood states (POMS) analysis, the participants were classified into two groups: control group (n=30) and depressive group (n=50). Leisure-time physical activity (LTPA), adrenal hormones such as ACTH, corticosterone (CORT), cortisol, DHEA/S, and cortisol:DHEA/S ratio were measured at baseline and post-intervention of moderate aerobic exercise for 12 weeks.Results: Older adults with higher depressive scores showed a remarkable change in the level of adrenal hormones compared to control. There was a significant increase in the level of ACTH, CORT, cortisol, and cortisol:DHEA/S ratio, and decrease in DHEA/S. Compared to females, males showed an improvement in depressive mood score along with an increase in LPTA, DHEA/S and decrease in ACTH, CORT, cortisol, cortisol:DHEA/S ratio following 12 weeks of supervised aerobic training, respectively.Conclusion: The findings of this study showed that 12 weeks of supervised exercise interventions are promising non-drug ... Article in Journal/Newspaper sami Dove Medical Press Clinical Interventions in Aging Volume 15 1271 1283 |
institution |
Open Polar |
collection |
Dove Medical Press |
op_collection_id |
ftdovepress |
language |
English |
topic |
Clinical Interventions in Aging |
spellingShingle |
Clinical Interventions in Aging Alghadir,Ahmad H Gabr,Sami A Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression |
topic_facet |
Clinical Interventions in Aging |
description |
Ahmad H Alghadir ,1 Sami A Gabr 1 Rehabilitation Research Chair (RRC), College of Applied Medical Sciences (CAMS), King Saud University, Riyadh, Kingdom of Saudi ArabiaCorrespondence: Sami A GabrRehabilitation Research Chair (RRC), College of Applied Medical Sciences (CAMS), King Saud University, P.O. Box 10219, Riyadh 11433, Kingdom of Saudi ArabiaTel +966 562060018Fax +966 14698541Email dr.samigabr@gmail.comBackground: Poor daily life physical activities among older people were related to depressive mood especially memory loss. In addition to that, the change in physical ability is significantly associated with the score of depression among older age.Objective: The present study aimed to evaluate the effects of a supervised aerobic training program with moderate intensity for 12 weeks on mood profiles and hormonal levels of the hypothalamus-pituitary-adrenal axis (HPA axis) of older adults.Methods: A total of 80 individuals of both gender (90 males, 110 females) of ages ranged between 65 and 95 years were recruited for this study. Based upon the profile of mood states (POMS) analysis, the participants were classified into two groups: control group (n=30) and depressive group (n=50). Leisure-time physical activity (LTPA), adrenal hormones such as ACTH, corticosterone (CORT), cortisol, DHEA/S, and cortisol:DHEA/S ratio were measured at baseline and post-intervention of moderate aerobic exercise for 12 weeks.Results: Older adults with higher depressive scores showed a remarkable change in the level of adrenal hormones compared to control. There was a significant increase in the level of ACTH, CORT, cortisol, and cortisol:DHEA/S ratio, and decrease in DHEA/S. Compared to females, males showed an improvement in depressive mood score along with an increase in LPTA, DHEA/S and decrease in ACTH, CORT, cortisol, cortisol:DHEA/S ratio following 12 weeks of supervised aerobic training, respectively.Conclusion: The findings of this study showed that 12 weeks of supervised exercise interventions are promising non-drug ... |
format |
Article in Journal/Newspaper |
author |
Alghadir,Ahmad H Gabr,Sami A |
author_facet |
Alghadir,Ahmad H Gabr,Sami A |
author_sort |
Alghadir,Ahmad H |
title |
Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression |
title_short |
Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression |
title_full |
Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression |
title_fullStr |
Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression |
title_full_unstemmed |
Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression |
title_sort |
hormonal function responses to moderate aerobic exercise in older adults with depression |
publisher |
Dove Press |
publishDate |
2020 |
url |
https://www.dovepress.com/hormonal-function-responses-to-moderate-aerobic-exercise-in-older-adul-peer-reviewed-fulltext-article-CIA |
genre |
sami |
genre_facet |
sami |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.2147/CIA.S259422 https://www.dovepress.com/hormonal-function-responses-to-moderate-aerobic-exercise-in-older-adul-peer-reviewed-fulltext-article-CIA |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.2147/CIA.S259422 |
container_title |
Clinical Interventions in Aging |
container_volume |
Volume 15 |
container_start_page |
1271 |
op_container_end_page |
1283 |
_version_ |
1766184549076697088 |