Impact of parental cancer on IQ, stress resilience, and physical fitness in young men
Ruoqing Chen,1 Katja Fall,1,2 Kamila Czene,1 Beatrice Kennedy,2 Unnur Valdimarsdóttir,1,3,4 Fang Fang1 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Swe...
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ftdovepress:oai:dovepress.com/38504 2023-05-15T16:49:04+02:00 Impact of parental cancer on IQ, stress resilience, and physical fitness in young men Chen,Ruoqing Fall,Katja Czene,Kamila Kennedy,Beatrice Valdimarsdóttir,Unnur Fang,Fang 2018-05-24 text/html https://www.dovepress.com/impact-of-parental-cancer-on-iq-stress-resilience-and-physical-fitness-peer-reviewed-fulltext-article-CLEP en eng Dove Press info:eu-repo/semantics/altIdentifier/doi/10.2147/CLEP.S152210 https://www.dovepress.com/impact-of-parental-cancer-on-iq-stress-resilience-and-physical-fitness-peer-reviewed-fulltext-article-CLEP info:eu-repo/semantics/openAccess Clinical Epidemiology Original Research info:eu-repo/semantics/article 2018 ftdovepress https://doi.org/10.2147/CLEP.S152210 2022-12-27T22:22:43Z Ruoqing Chen,1 Katja Fall,1,2 Kamila Czene,1 Beatrice Kennedy,2 Unnur Valdimarsdóttir,1,3,4 Fang Fang1 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden; 3Centre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavík, Iceland; 4Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA Background: A parental cancer diagnosis is a stressful life event, potentially leading to increased risks of mental and physical problems among children. This study aimed to investigate the associations of parental cancer with IQ, stress resilience, and physical fitness of the affected men during early adulthood. Materials and methods: In this Swedish population-based study, we included 465,249 men born during 1973–1983 who underwent the military conscription examination around the age of 18 years. We identified cancer diagnoses among the parents of these men from the Cancer Register. IQ, stress resilience, and physical fitness of the men were assessed at the time of conscription and categorized into three levels: low, moderate, and high (reference category). We used multinomial logistic regression to assess the studied associations. Results: Overall, parental cancer was associated with higher risks of low stress resilience (relative risk ratio [RRR]: 1.09 [95% confidence interval (CI) 1.04–1.15]) and low physical fitness (RRR: 1.12 [95% CI 1.05–1.19]). Stronger associations were observed for parental cancer with a poor expected prognosis (low stress resilience: RRR: 1.59 [95% CI 1.31–1.94]; low physical fitness: RRR: 1.45 [95% CI 1.14–1.85]) and for parental death after cancer diagnosis (low stress resilience: RRR: 1.29 [95% CI 1.16–1.43]; low physical fitness: RRR: 1.40 [95% CI 1.23–1.59]). Although there was no overall association between parental cancer and IQ, parental death after cancer diagnosis was associated with a higher ... Article in Journal/Newspaper Iceland Reykjavík Reykjavík Dove Medical Press Fang ENVELOPE(167.217,167.217,-77.483,-77.483) Reykjavík Clinical Epidemiology Volume 10 593 604 |
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Clinical Epidemiology |
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Clinical Epidemiology Chen,Ruoqing Fall,Katja Czene,Kamila Kennedy,Beatrice Valdimarsdóttir,Unnur Fang,Fang Impact of parental cancer on IQ, stress resilience, and physical fitness in young men |
topic_facet |
Clinical Epidemiology |
description |
Ruoqing Chen,1 Katja Fall,1,2 Kamila Czene,1 Beatrice Kennedy,2 Unnur Valdimarsdóttir,1,3,4 Fang Fang1 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden; 3Centre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavík, Iceland; 4Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA Background: A parental cancer diagnosis is a stressful life event, potentially leading to increased risks of mental and physical problems among children. This study aimed to investigate the associations of parental cancer with IQ, stress resilience, and physical fitness of the affected men during early adulthood. Materials and methods: In this Swedish population-based study, we included 465,249 men born during 1973–1983 who underwent the military conscription examination around the age of 18 years. We identified cancer diagnoses among the parents of these men from the Cancer Register. IQ, stress resilience, and physical fitness of the men were assessed at the time of conscription and categorized into three levels: low, moderate, and high (reference category). We used multinomial logistic regression to assess the studied associations. Results: Overall, parental cancer was associated with higher risks of low stress resilience (relative risk ratio [RRR]: 1.09 [95% confidence interval (CI) 1.04–1.15]) and low physical fitness (RRR: 1.12 [95% CI 1.05–1.19]). Stronger associations were observed for parental cancer with a poor expected prognosis (low stress resilience: RRR: 1.59 [95% CI 1.31–1.94]; low physical fitness: RRR: 1.45 [95% CI 1.14–1.85]) and for parental death after cancer diagnosis (low stress resilience: RRR: 1.29 [95% CI 1.16–1.43]; low physical fitness: RRR: 1.40 [95% CI 1.23–1.59]). Although there was no overall association between parental cancer and IQ, parental death after cancer diagnosis was associated with a higher ... |
format |
Article in Journal/Newspaper |
author |
Chen,Ruoqing Fall,Katja Czene,Kamila Kennedy,Beatrice Valdimarsdóttir,Unnur Fang,Fang |
author_facet |
Chen,Ruoqing Fall,Katja Czene,Kamila Kennedy,Beatrice Valdimarsdóttir,Unnur Fang,Fang |
author_sort |
Chen,Ruoqing |
title |
Impact of parental cancer on IQ, stress resilience, and physical fitness in young men |
title_short |
Impact of parental cancer on IQ, stress resilience, and physical fitness in young men |
title_full |
Impact of parental cancer on IQ, stress resilience, and physical fitness in young men |
title_fullStr |
Impact of parental cancer on IQ, stress resilience, and physical fitness in young men |
title_full_unstemmed |
Impact of parental cancer on IQ, stress resilience, and physical fitness in young men |
title_sort |
impact of parental cancer on iq, stress resilience, and physical fitness in young men |
publisher |
Dove Press |
publishDate |
2018 |
url |
https://www.dovepress.com/impact-of-parental-cancer-on-iq-stress-resilience-and-physical-fitness-peer-reviewed-fulltext-article-CLEP |
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ENVELOPE(167.217,167.217,-77.483,-77.483) |
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Fang Reykjavík |
geographic_facet |
Fang Reykjavík |
genre |
Iceland Reykjavík Reykjavík |
genre_facet |
Iceland Reykjavík Reykjavík |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.2147/CLEP.S152210 https://www.dovepress.com/impact-of-parental-cancer-on-iq-stress-resilience-and-physical-fitness-peer-reviewed-fulltext-article-CLEP |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.2147/CLEP.S152210 |
container_title |
Clinical Epidemiology |
container_volume |
Volume 10 |
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593 |
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604 |
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1766039143259832320 |