Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc-CTL-1 and Tc-TES-26.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: John P Anderson, Lisa N Rascoe, Keith Levert, Holly M Chastain, Matthew S Reed, Hilda N Rivera, Isabel McAuliffe, Bin Zhan, Ryan E Wiegand, Peter J Hotez, Patricia P Wilkins, Jan Pohl, Sukwan Handali
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2015
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Eia
• Online Access: https://doi.org/10.1371/journal.pntd.0004168; https://doaj.org/article/ff0ff80eda244542b4c6026165372019

The clinical spectrum of human disease caused by the roundworms Toxocara canis and Toxocara cati ranges from visceral and ocular larva migrans to covert toxocariasis. The parasite is not typically recovered in affected tissues, so detection of parasite-specific antibodies is usually necessary for es...