Field assessment in Cameroon of a reader of POC-CCA lateral flow strips for the quantification of Schistosoma mansoni circulating cathodic antigen in urine.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Estelle Mezajou Mewamba, Arnol Auvaker Zebaze Tiofack, Cyrille Nguemnang Kamdem, Romuald Isaka Kamwa Ngassam, Mureille Carole Tchami Mbagnia, Oscar Nyangiri, Harry Noyes, Hilaire Marcaire Womeni, Flobert Njiokou, Gustave Simo
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2021
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Rho
• Online Access: https://doi.org/10.1371/journal.pntd.0009569; https://doaj.org/article/fec351f982274cd1a661d35cd50df0ec

Background Determining Schistosoma mansoni infection rate and intensity is challenging due to the low sensitivity of the Kato-Katz (KK) test that underestimates the true disease prevalence. Circulating cathodic antigen (CCA) excreted in urine is constantly produced by adult worms and has been used a...