A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient
Forty patients with a diagnosis of snake bite were studied at the Infectious and Parasitic Disease Service of the Faculty of Medicine of Botucatu. Thirty were males and 10 females, ranging in age from 16 to 70 years. All were farm laborers and 35 of them were bitten in the lower limbs. Two of the 9...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1989
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ftdoajarticles:oai:doaj.org/article:fde0da07b8ab4d509cb85deb1079cfe5 2023-05-15T15:18:38+02:00 A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient Benedito Barraviera José Carlos Bonjorno Junior Denise Arakaki Maria Aparecida C. Domingues Paulo Camara Marques Pereira Rinaldo P. Mendes Jussara Marcondes Machado Domingos Alves Meira 1989-03-01T00:00:00Z https://doaj.org/article/fde0da07b8ab4d509cb85deb1079cfe5 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821989000100002 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/fde0da07b8ab4d509cb85deb1079cfe5 Revista da Sociedade Brasileira de Medicina Tropical, Vol 22, Iss 1, Pp 5-12 (1989) Acidente crotálico Necrose hepática Crotalus snake bite Hepatic necrosis Arctic medicine. Tropical medicine RC955-962 article 1989 ftdoajarticles 2022-12-31T03:20:40Z Forty patients with a diagnosis of snake bite were studied at the Infectious and Parasitic Disease Service of the Faculty of Medicine of Botucatu. Thirty were males and 10 females, ranging in age from 16 to 70 years. All were farm laborers and 35 of them were bitten in the lower limbs. Two of the 9 patients seen more than 6 hours after the bite died. The low mortality rate (5%) observed could be explained by the early care provided, by the use of appropriate doses of anti-crotalus serum, parenteral hydration, urine alkalinization with sodium bicarbonate and induction of osmotic diuresis with a mannitol solution. Anatomopathological examination of one of the patients who died revealed extensive hepatic necrosis. The authors discuss the possibility of the effect of a factor of snake venom in the genesis of hepatic necrosis and in the increased transaminase levels. Os autores avaliaram 40 doentes com diagnóstico de acidente crotálico, atendidos no Serviço de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina de Botucatu. Desses, 30 eram do sexo masculino e 10 do feminino, com idades variando entre 16 e 70 anos. Todos eram lavradores e 35 deles foram atingidos nos membros inferiores. A maioria dos doentes (31) foi atendida antes de 6 horas do acidente. Dos 9 que receberam atendimento médico após 6 horas, 2 deles evoluíram para o óbito. Os resultados observados revelaram que o baixo índice de mortalidade (5%) verificado pode eventualmente ser explicado pelo atendimento precoce, uso de doses adequadas de soro anticrotálico, hidratação parenteral, alcalinização da urina com bicarbonato de sódio e indução da diurese osmótica com solução de manitol. O exame anatomopatológico de um dos casos que evoluiu para o óbito apresentou extensa necrose hepática. Os autores discutem a possibilidade de interação entre alcoolismo crônico e a ação eventual de um fator hepatotóxico do veneno da serpente na gênese da necrose hepática e no aumento dos níveis de transaminases. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Acidente crotálico Necrose hepática Crotalus snake bite Hepatic necrosis Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Acidente crotálico Necrose hepática Crotalus snake bite Hepatic necrosis Arctic medicine. Tropical medicine RC955-962 Benedito Barraviera José Carlos Bonjorno Junior Denise Arakaki Maria Aparecida C. Domingues Paulo Camara Marques Pereira Rinaldo P. Mendes Jussara Marcondes Machado Domingos Alves Meira A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
topic_facet |
Acidente crotálico Necrose hepática Crotalus snake bite Hepatic necrosis Arctic medicine. Tropical medicine RC955-962 |
description |
Forty patients with a diagnosis of snake bite were studied at the Infectious and Parasitic Disease Service of the Faculty of Medicine of Botucatu. Thirty were males and 10 females, ranging in age from 16 to 70 years. All were farm laborers and 35 of them were bitten in the lower limbs. Two of the 9 patients seen more than 6 hours after the bite died. The low mortality rate (5%) observed could be explained by the early care provided, by the use of appropriate doses of anti-crotalus serum, parenteral hydration, urine alkalinization with sodium bicarbonate and induction of osmotic diuresis with a mannitol solution. Anatomopathological examination of one of the patients who died revealed extensive hepatic necrosis. The authors discuss the possibility of the effect of a factor of snake venom in the genesis of hepatic necrosis and in the increased transaminase levels. Os autores avaliaram 40 doentes com diagnóstico de acidente crotálico, atendidos no Serviço de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina de Botucatu. Desses, 30 eram do sexo masculino e 10 do feminino, com idades variando entre 16 e 70 anos. Todos eram lavradores e 35 deles foram atingidos nos membros inferiores. A maioria dos doentes (31) foi atendida antes de 6 horas do acidente. Dos 9 que receberam atendimento médico após 6 horas, 2 deles evoluíram para o óbito. Os resultados observados revelaram que o baixo índice de mortalidade (5%) verificado pode eventualmente ser explicado pelo atendimento precoce, uso de doses adequadas de soro anticrotálico, hidratação parenteral, alcalinização da urina com bicarbonato de sódio e indução da diurese osmótica com solução de manitol. O exame anatomopatológico de um dos casos que evoluiu para o óbito apresentou extensa necrose hepática. Os autores discutem a possibilidade de interação entre alcoolismo crônico e a ação eventual de um fator hepatotóxico do veneno da serpente na gênese da necrose hepática e no aumento dos níveis de transaminases. |
format |
Article in Journal/Newspaper |
author |
Benedito Barraviera José Carlos Bonjorno Junior Denise Arakaki Maria Aparecida C. Domingues Paulo Camara Marques Pereira Rinaldo P. Mendes Jussara Marcondes Machado Domingos Alves Meira |
author_facet |
Benedito Barraviera José Carlos Bonjorno Junior Denise Arakaki Maria Aparecida C. Domingues Paulo Camara Marques Pereira Rinaldo P. Mendes Jussara Marcondes Machado Domingos Alves Meira |
author_sort |
Benedito Barraviera |
title |
A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
title_short |
A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
title_full |
A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
title_fullStr |
A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
title_full_unstemmed |
A retrospective study of 40 victims of Crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
title_sort |
retrospective study of 40 victims of crotalus snake bites: analysis of the hepatic necrosis observed in one patient |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1989 |
url |
https://doaj.org/article/fde0da07b8ab4d509cb85deb1079cfe5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 22, Iss 1, Pp 5-12 (1989) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821989000100002 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/fde0da07b8ab4d509cb85deb1079cfe5 |
_version_ |
1766348822444769280 |