Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus.
Most mosquito control efforts are primarily focused on reducing the adult population size mediated by reductions in the larval population, which should lower risk of disease transmission. Although the aim of larviciding is to reduce larval abundance and thus recruitment of adults, nonlethal effects...
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ftdoajarticles:oai:doaj.org/article:fd775ce181eb44d2a0c7bf7778c5b669 2023-05-15T15:14:19+02:00 Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. Barry W Alto Cynthia C Lord 2016-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004370 https://doaj.org/article/fd775ce181eb44d2a0c7bf7778c5b669 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4752348?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004370 https://doaj.org/article/fd775ce181eb44d2a0c7bf7778c5b669 PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004370 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004370 2022-12-31T05:33:52Z Most mosquito control efforts are primarily focused on reducing the adult population size mediated by reductions in the larval population, which should lower risk of disease transmission. Although the aim of larviciding is to reduce larval abundance and thus recruitment of adults, nonlethal effects on adults are possible, including transstadial effects on phenotypes of adults such as survival and pathogen infection and transmission. In addition, the mortality induced by control efforts may act in conjunction with other sources of mosquito mortality in nature. The consequences of these effects and interactions may alter the potential of the population to transmit pathogens. We tested experimentally the combined effects of a larvicide (Bacillus thuringiensis ssp. israelensis, Bti) and competition during the larval stages on subsequent Aedes aegypti (Linnaeus) traits, population performance, and susceptibility to dengue-1 virus infection. Ae. aegypti that survived exposure to Bti experienced accelerated development, were larger, and produced more eggs with increasing amounts of Bti, consistent with competitive release among surviving mosquitoes. Changing larval density had no significant interactive effect with Bti treatment on development and growth to adulthood. Larval density, but not Bti or treatment interaction, had a strong effect on survival of adult Ae. aegypti females. There were sharper declines in cumulative daily survival of adults from crowded than uncrowded larval conditions, suggesting that high competition conditions of larvae may be an impediment to transmission of dengue viruses. Rates of infection and dengue-1 virus disseminated infections were found to be 87±13% and 88±12%, respectively. There were no significant treatment effects on infection measurements. Our findings suggest that larvicide campaigns using Bti may reduce the number of emerged adults, but survivors will have a fitness advantage (growth, development, enhanced production of eggs) relative to conspecifics that are not under ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 2 e0004370 |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Barry W Alto Cynthia C Lord Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Most mosquito control efforts are primarily focused on reducing the adult population size mediated by reductions in the larval population, which should lower risk of disease transmission. Although the aim of larviciding is to reduce larval abundance and thus recruitment of adults, nonlethal effects on adults are possible, including transstadial effects on phenotypes of adults such as survival and pathogen infection and transmission. In addition, the mortality induced by control efforts may act in conjunction with other sources of mosquito mortality in nature. The consequences of these effects and interactions may alter the potential of the population to transmit pathogens. We tested experimentally the combined effects of a larvicide (Bacillus thuringiensis ssp. israelensis, Bti) and competition during the larval stages on subsequent Aedes aegypti (Linnaeus) traits, population performance, and susceptibility to dengue-1 virus infection. Ae. aegypti that survived exposure to Bti experienced accelerated development, were larger, and produced more eggs with increasing amounts of Bti, consistent with competitive release among surviving mosquitoes. Changing larval density had no significant interactive effect with Bti treatment on development and growth to adulthood. Larval density, but not Bti or treatment interaction, had a strong effect on survival of adult Ae. aegypti females. There were sharper declines in cumulative daily survival of adults from crowded than uncrowded larval conditions, suggesting that high competition conditions of larvae may be an impediment to transmission of dengue viruses. Rates of infection and dengue-1 virus disseminated infections were found to be 87±13% and 88±12%, respectively. There were no significant treatment effects on infection measurements. Our findings suggest that larvicide campaigns using Bti may reduce the number of emerged adults, but survivors will have a fitness advantage (growth, development, enhanced production of eggs) relative to conspecifics that are not under ... |
format |
Article in Journal/Newspaper |
author |
Barry W Alto Cynthia C Lord |
author_facet |
Barry W Alto Cynthia C Lord |
author_sort |
Barry W Alto |
title |
Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. |
title_short |
Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. |
title_full |
Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. |
title_fullStr |
Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. |
title_full_unstemmed |
Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus. |
title_sort |
transstadial effects of bti on traits of aedes aegypti and infection with dengue virus. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004370 https://doaj.org/article/fd775ce181eb44d2a0c7bf7778c5b669 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004370 (2016) |
op_relation |
http://europepmc.org/articles/PMC4752348?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004370 https://doaj.org/article/fd775ce181eb44d2a0c7bf7778c5b669 |
op_doi |
https://doi.org/10.1371/journal.pntd.0004370 |
container_title |
PLOS Neglected Tropical Diseases |
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10 |
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2 |
container_start_page |
e0004370 |
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