Effect of BMI and urinary pH on urolithiasis and its composition
Urolithiasis is a common urological disease predominantly affecting males. The lifetime risk of urolithiasis varies from 1% to 5% in Asia, 5% to 9% in Europe, 10% to 15% in the USA and 20% to 25% in the middle-east; lowest prevalence is reported from Greenland and Japan. Such differences have been e...
Published in: | Saudi Journal of Kidney Diseases and Transplantation |
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Wolters Kluwer Medknow Publications
2013
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ftdoajarticles:oai:doaj.org/article:fd47eebdbf714b6d92839b762563bfa3 2023-05-15T16:30:32+02:00 Effect of BMI and urinary pH on urolithiasis and its composition Qazi Najeeb Imran Masood Neeru Bhaskar Harnam Kaur Jasbir Singh Rajesh Pandey K S Sodhi Suvarna Prasad Sheikh Ishaq Ruhi Mahajan 2013-01-01T00:00:00Z https://doi.org/10.4103/1319-2442.106243 https://doaj.org/article/fd47eebdbf714b6d92839b762563bfa3 EN eng Wolters Kluwer Medknow Publications http://www.sjkdt.org/article.asp?issn=1319-2442;year=2013;volume=24;issue=1;spage=60;epage=66;aulast=Najeeb https://doaj.org/toc/1319-2442 1319-2442 doi:10.4103/1319-2442.106243 https://doaj.org/article/fd47eebdbf714b6d92839b762563bfa3 Saudi Journal of Kidney Diseases and Transplantation, Vol 24, Iss 1, Pp 60-66 (2013) Medicine R article 2013 ftdoajarticles https://doi.org/10.4103/1319-2442.106243 2022-12-31T12:22:36Z Urolithiasis is a common urological disease predominantly affecting males. The lifetime risk of urolithiasis varies from 1% to 5% in Asia, 5% to 9% in Europe, 10% to 15% in the USA and 20% to 25% in the middle-east; lowest prevalence is reported from Greenland and Japan. Such differences have been explained on the basis of race, diet and climate factors. Furthermore, changing socio-economic conditions have generated changes in the prevalence, incidence and distribution for age, sex and type of lithiasis in terms of both the site and the chemical as well as the physical composition of the calculi. The aim of our study was to determine the association between body mass index (BMI) and urine pH in patients with urolithiasis and the influence of body size, as reflected by the BMI, on the composition. The study was conducted in the Department of Biochemistry, Maharishi Markandeshwar Institute of Medical Sciences and Research, on urolithiatic patients. The data included patient′s age, sex, BMI, urine pH, serum calcium, serum uric acid, serum creatinine and stone composition. Data from 100 patients, 70 men (70%) and 30 women (30%), were analyzed, with 28 patients having normal weight, 38 patients being overweight and 34 patients being obese. The mean age of the patients was 36.58 ± 9.91 years in group I, 40.47 ± 14.48 years in group II and 37.85 ± 12.46 years in group III (P > 0.05). The stone composition was calcium oxalate (CaOx) in 66 patients, calcium phosphate (CaP) in 60 patients, uric acid (UA) in 38 patients, combined calcium oxalate and calcium phosphate in 28 patients and three stones in 10 patients. The urinary pH levels (mean ± SD) were 7.78 ± 1.49 in group I, 7.15 ± 1.11 in group II and 6.29 ± 1.14 in group III patients (P = 0.0001). Urine pH showed a stepwise decrease with increasing BMI (inverse correlation). Urine pH is inversely related to BMI among patients with urolithiasis, as is the occurrence of urate, calcium oxalate and calcium phosphate stones. Similarly, the serum creatinine increased as ... Article in Journal/Newspaper Greenland Directory of Open Access Journals: DOAJ Articles Greenland Saudi Journal of Kidney Diseases and Transplantation 24 1 60 |
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Medicine R Qazi Najeeb Imran Masood Neeru Bhaskar Harnam Kaur Jasbir Singh Rajesh Pandey K S Sodhi Suvarna Prasad Sheikh Ishaq Ruhi Mahajan Effect of BMI and urinary pH on urolithiasis and its composition |
topic_facet |
Medicine R |
description |
Urolithiasis is a common urological disease predominantly affecting males. The lifetime risk of urolithiasis varies from 1% to 5% in Asia, 5% to 9% in Europe, 10% to 15% in the USA and 20% to 25% in the middle-east; lowest prevalence is reported from Greenland and Japan. Such differences have been explained on the basis of race, diet and climate factors. Furthermore, changing socio-economic conditions have generated changes in the prevalence, incidence and distribution for age, sex and type of lithiasis in terms of both the site and the chemical as well as the physical composition of the calculi. The aim of our study was to determine the association between body mass index (BMI) and urine pH in patients with urolithiasis and the influence of body size, as reflected by the BMI, on the composition. The study was conducted in the Department of Biochemistry, Maharishi Markandeshwar Institute of Medical Sciences and Research, on urolithiatic patients. The data included patient′s age, sex, BMI, urine pH, serum calcium, serum uric acid, serum creatinine and stone composition. Data from 100 patients, 70 men (70%) and 30 women (30%), were analyzed, with 28 patients having normal weight, 38 patients being overweight and 34 patients being obese. The mean age of the patients was 36.58 ± 9.91 years in group I, 40.47 ± 14.48 years in group II and 37.85 ± 12.46 years in group III (P > 0.05). The stone composition was calcium oxalate (CaOx) in 66 patients, calcium phosphate (CaP) in 60 patients, uric acid (UA) in 38 patients, combined calcium oxalate and calcium phosphate in 28 patients and three stones in 10 patients. The urinary pH levels (mean ± SD) were 7.78 ± 1.49 in group I, 7.15 ± 1.11 in group II and 6.29 ± 1.14 in group III patients (P = 0.0001). Urine pH showed a stepwise decrease with increasing BMI (inverse correlation). Urine pH is inversely related to BMI among patients with urolithiasis, as is the occurrence of urate, calcium oxalate and calcium phosphate stones. Similarly, the serum creatinine increased as ... |
format |
Article in Journal/Newspaper |
author |
Qazi Najeeb Imran Masood Neeru Bhaskar Harnam Kaur Jasbir Singh Rajesh Pandey K S Sodhi Suvarna Prasad Sheikh Ishaq Ruhi Mahajan |
author_facet |
Qazi Najeeb Imran Masood Neeru Bhaskar Harnam Kaur Jasbir Singh Rajesh Pandey K S Sodhi Suvarna Prasad Sheikh Ishaq Ruhi Mahajan |
author_sort |
Qazi Najeeb |
title |
Effect of BMI and urinary pH on urolithiasis and its composition |
title_short |
Effect of BMI and urinary pH on urolithiasis and its composition |
title_full |
Effect of BMI and urinary pH on urolithiasis and its composition |
title_fullStr |
Effect of BMI and urinary pH on urolithiasis and its composition |
title_full_unstemmed |
Effect of BMI and urinary pH on urolithiasis and its composition |
title_sort |
effect of bmi and urinary ph on urolithiasis and its composition |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2013 |
url |
https://doi.org/10.4103/1319-2442.106243 https://doaj.org/article/fd47eebdbf714b6d92839b762563bfa3 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland |
genre_facet |
Greenland |
op_source |
Saudi Journal of Kidney Diseases and Transplantation, Vol 24, Iss 1, Pp 60-66 (2013) |
op_relation |
http://www.sjkdt.org/article.asp?issn=1319-2442;year=2013;volume=24;issue=1;spage=60;epage=66;aulast=Najeeb https://doaj.org/toc/1319-2442 1319-2442 doi:10.4103/1319-2442.106243 https://doaj.org/article/fd47eebdbf714b6d92839b762563bfa3 |
op_doi |
https://doi.org/10.4103/1319-2442.106243 |
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Saudi Journal of Kidney Diseases and Transplantation |
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24 |
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60 |
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1766020270170046464 |