Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations
Abstract Background Malaria may be perennial or epidemic in sub-Saharan Africa, and its transmission may be stable or unstable, depending on the region. The prevalence of asymptomatic Plasmodium falciparum carriage is poorly documented in Gabon. A large survey of P. falciparum infection was conducte...
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ftdoajarticles:oai:doaj.org/article:fcf7e6b029bc404da5529db8505c8f51 2023-05-15T15:09:42+02:00 Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations Gonzalez Jean-Paul Akue Jean-Paul Nkoghe Dieudonné Leroy Eric M 2011-02-01T00:00:00Z https://doi.org/10.1186/1475-2875-10-33 https://doaj.org/article/fcf7e6b029bc404da5529db8505c8f51 EN eng BMC http://www.malariajournal.com/content/10/1/33 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-33 1475-2875 https://doaj.org/article/fcf7e6b029bc404da5529db8505c8f51 Malaria Journal, Vol 10, Iss 1, p 33 (2011) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2011 ftdoajarticles https://doi.org/10.1186/1475-2875-10-33 2022-12-31T04:55:35Z Abstract Background Malaria may be perennial or epidemic in sub-Saharan Africa, and its transmission may be stable or unstable, depending on the region. The prevalence of asymptomatic Plasmodium falciparum carriage is poorly documented in Gabon. A large survey of P. falciparum infection was conducted in asymptomatic individuals living in rural Gabon. Methods Two hundred and twenty-two villages were randomly selected in the nine administrative regions. With the participants' informed consent, blood samples were collected for thick and thin blood film examination after 20% Giemsa staining. Prevalence rates were calculated per village, per region and per ecosystem, and nationwide. Demographic risk factors were identified with STATA software version 9.0. Significance was assumed at p < 0.05. Results and discussion The prevalence of P. falciparum in adults was 6.2% (269/4342) nationwide, with a maximum of 37.2% in one village; a linear decrease was observed with increasing age (p = 0.045). Only 5% of the 399 children from forest areas tested positive. The prevalence was significantly higher in forest areas (7%) than in savannah (4%) and lakeland (2.5%). Within the forest region, the prevalence was significantly higher in forest grassland (10.9%) than in the mountain forest (3.5%), interior forest (6.8%) and north-eastern forest (4.5%). Conclusion Plasmodium falciparum carriage remains high among adults in rural Gabon. Control measures must be adapted to the region and ecosystem. Routine treatment of asymptomatic individuals should be considered. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 10 1 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Gonzalez Jean-Paul Akue Jean-Paul Nkoghe Dieudonné Leroy Eric M Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria may be perennial or epidemic in sub-Saharan Africa, and its transmission may be stable or unstable, depending on the region. The prevalence of asymptomatic Plasmodium falciparum carriage is poorly documented in Gabon. A large survey of P. falciparum infection was conducted in asymptomatic individuals living in rural Gabon. Methods Two hundred and twenty-two villages were randomly selected in the nine administrative regions. With the participants' informed consent, blood samples were collected for thick and thin blood film examination after 20% Giemsa staining. Prevalence rates were calculated per village, per region and per ecosystem, and nationwide. Demographic risk factors were identified with STATA software version 9.0. Significance was assumed at p < 0.05. Results and discussion The prevalence of P. falciparum in adults was 6.2% (269/4342) nationwide, with a maximum of 37.2% in one village; a linear decrease was observed with increasing age (p = 0.045). Only 5% of the 399 children from forest areas tested positive. The prevalence was significantly higher in forest areas (7%) than in savannah (4%) and lakeland (2.5%). Within the forest region, the prevalence was significantly higher in forest grassland (10.9%) than in the mountain forest (3.5%), interior forest (6.8%) and north-eastern forest (4.5%). Conclusion Plasmodium falciparum carriage remains high among adults in rural Gabon. Control measures must be adapted to the region and ecosystem. Routine treatment of asymptomatic individuals should be considered. |
format |
Article in Journal/Newspaper |
author |
Gonzalez Jean-Paul Akue Jean-Paul Nkoghe Dieudonné Leroy Eric M |
author_facet |
Gonzalez Jean-Paul Akue Jean-Paul Nkoghe Dieudonné Leroy Eric M |
author_sort |
Gonzalez Jean-Paul |
title |
Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations |
title_short |
Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations |
title_full |
Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations |
title_fullStr |
Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations |
title_full_unstemmed |
Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations |
title_sort |
prevalence of plasmodium falciparum infection in asymptomatic rural gabonese populations |
publisher |
BMC |
publishDate |
2011 |
url |
https://doi.org/10.1186/1475-2875-10-33 https://doaj.org/article/fcf7e6b029bc404da5529db8505c8f51 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 10, Iss 1, p 33 (2011) |
op_relation |
http://www.malariajournal.com/content/10/1/33 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-33 1475-2875 https://doaj.org/article/fcf7e6b029bc404da5529db8505c8f51 |
op_doi |
https://doi.org/10.1186/1475-2875-10-33 |
container_title |
Malaria Journal |
container_volume |
10 |
container_issue |
1 |
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1766340839079936000 |