Asymptomatic median neuropathy in patients with diabetic polyneuropathy
Aim: This study aims to investigate whether asymptomatic median neuropathy (AMN) in patients with diabetic peripheral polyneuropathy (DPNP) is a result of polyneuropathic involvement of median nerve (MN) or its true entrapment. Subjects and Methods: We determined the grades of the Michigan severity...
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ftdoajarticles:oai:doaj.org/article:fcc577d235b74de5a797e44ff8db30d7 2023-05-15T16:01:48+02:00 Asymptomatic median neuropathy in patients with diabetic polyneuropathy Murat Alemdar 2021-01-01T00:00:00Z https://doi.org/10.4103/nsn.nsn_54_21 https://doaj.org/article/fcc577d235b74de5a797e44ff8db30d7 EN eng Wolters Kluwer Medknow Publications http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2021;volume=38;issue=4;spage=234;epage=244;aulast=Alemdar https://doaj.org/toc/2636-865X 2636-865X doi:10.4103/nsn.nsn_54_21 https://doaj.org/article/fcc577d235b74de5a797e44ff8db30d7 Neurological Sciences and Neurophysiology, Vol 38, Iss 4, Pp 234-244 (2021) carpal tunnel syndrome diabetic polyneuropathy nerve compression Neurology. Diseases of the nervous system RC346-429 article 2021 ftdoajarticles https://doi.org/10.4103/nsn.nsn_54_21 2022-12-31T10:58:48Z Aim: This study aims to investigate whether asymptomatic median neuropathy (AMN) in patients with diabetic peripheral polyneuropathy (DPNP) is a result of polyneuropathic involvement of median nerve (MN) or its true entrapment. Subjects and Methods: We determined the grades of the Michigan severity scale and the rates of peripheral nerve conduction abnormalities in study subgroups, including patients with carpal tunnel syndrome (CTS), AMN, and normal MN conductions to highlight if the severity of polyneuropathic involvement was different between them. In addition, the results of conventional and comparative nerve conduction studies (NCSs) were compared between these study subgroups. Results: Distributions of Michigan grades and rates of abnormalities in peroneal and sural NCSs were similar between the subgroups (P > 0.05 for all analyses). Abnormality rates of ulnar NCSs were higher in the AMN group than in the other groups, whereas those of comparative transcarpal NCSs were higher in the CTS group. The mean distal sensory latency (DSL) and motor latency (DML) of MN were longer, sensory conduction velocity (SCV) was slower in the CTS group than AMN group, whereas MN motor conduction velocity (MCV) was slower, UN DSL was longer, SCV was slower, SNAP amplitude was smaller, DML was longer, and MCV were slower in the AMN group (P < 0.05 for all analyses). Discussion: Our findings reveal that grade of polyneuropathic involvement is more prominent in AMN, whereas transcarpal MN conduction delay is greater in CTS. The results of the study suggest that the prominence of polyneuropathic impairment in addition to a lesser degree of MN sheet compression obscures the clinical signs in patients with diabetes with AMN. Article in Journal/Newspaper DML Directory of Open Access Journals: DOAJ Articles |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
carpal tunnel syndrome diabetic polyneuropathy nerve compression Neurology. Diseases of the nervous system RC346-429 |
spellingShingle |
carpal tunnel syndrome diabetic polyneuropathy nerve compression Neurology. Diseases of the nervous system RC346-429 Murat Alemdar Asymptomatic median neuropathy in patients with diabetic polyneuropathy |
topic_facet |
carpal tunnel syndrome diabetic polyneuropathy nerve compression Neurology. Diseases of the nervous system RC346-429 |
description |
Aim: This study aims to investigate whether asymptomatic median neuropathy (AMN) in patients with diabetic peripheral polyneuropathy (DPNP) is a result of polyneuropathic involvement of median nerve (MN) or its true entrapment. Subjects and Methods: We determined the grades of the Michigan severity scale and the rates of peripheral nerve conduction abnormalities in study subgroups, including patients with carpal tunnel syndrome (CTS), AMN, and normal MN conductions to highlight if the severity of polyneuropathic involvement was different between them. In addition, the results of conventional and comparative nerve conduction studies (NCSs) were compared between these study subgroups. Results: Distributions of Michigan grades and rates of abnormalities in peroneal and sural NCSs were similar between the subgroups (P > 0.05 for all analyses). Abnormality rates of ulnar NCSs were higher in the AMN group than in the other groups, whereas those of comparative transcarpal NCSs were higher in the CTS group. The mean distal sensory latency (DSL) and motor latency (DML) of MN were longer, sensory conduction velocity (SCV) was slower in the CTS group than AMN group, whereas MN motor conduction velocity (MCV) was slower, UN DSL was longer, SCV was slower, SNAP amplitude was smaller, DML was longer, and MCV were slower in the AMN group (P < 0.05 for all analyses). Discussion: Our findings reveal that grade of polyneuropathic involvement is more prominent in AMN, whereas transcarpal MN conduction delay is greater in CTS. The results of the study suggest that the prominence of polyneuropathic impairment in addition to a lesser degree of MN sheet compression obscures the clinical signs in patients with diabetes with AMN. |
format |
Article in Journal/Newspaper |
author |
Murat Alemdar |
author_facet |
Murat Alemdar |
author_sort |
Murat Alemdar |
title |
Asymptomatic median neuropathy in patients with diabetic polyneuropathy |
title_short |
Asymptomatic median neuropathy in patients with diabetic polyneuropathy |
title_full |
Asymptomatic median neuropathy in patients with diabetic polyneuropathy |
title_fullStr |
Asymptomatic median neuropathy in patients with diabetic polyneuropathy |
title_full_unstemmed |
Asymptomatic median neuropathy in patients with diabetic polyneuropathy |
title_sort |
asymptomatic median neuropathy in patients with diabetic polyneuropathy |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2021 |
url |
https://doi.org/10.4103/nsn.nsn_54_21 https://doaj.org/article/fcc577d235b74de5a797e44ff8db30d7 |
genre |
DML |
genre_facet |
DML |
op_source |
Neurological Sciences and Neurophysiology, Vol 38, Iss 4, Pp 234-244 (2021) |
op_relation |
http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2021;volume=38;issue=4;spage=234;epage=244;aulast=Alemdar https://doaj.org/toc/2636-865X 2636-865X doi:10.4103/nsn.nsn_54_21 https://doaj.org/article/fcc577d235b74de5a797e44ff8db30d7 |
op_doi |
https://doi.org/10.4103/nsn.nsn_54_21 |
_version_ |
1766397517538263040 |