The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria
In 2005, Nigeria changed its antimalarial drug policy to Artemisinin-based Combination Therapies (ACTs) for the treatment of malaria infection, and it is imperative for prescribers to strictly comply with this guideline to harmonize malaria management practices within the country. This study aims to...
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ftdoajarticles:oai:doaj.org/article:fb8406f5033c4cb9b927bc97c0302754 2023-05-15T15:06:29+02:00 The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria Roland Nnaemeka Okoro Muslim Olakunle Jamiu 2018-01-01T00:00:00Z https://doi.org/10.1155/2018/2025858 https://doaj.org/article/fb8406f5033c4cb9b927bc97c0302754 EN eng Hindawi Limited http://dx.doi.org/10.1155/2018/2025858 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2018/2025858 https://doaj.org/article/fb8406f5033c4cb9b927bc97c0302754 Journal of Tropical Medicine, Vol 2018 (2018) Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.1155/2018/2025858 2022-12-31T14:16:07Z In 2005, Nigeria changed its antimalarial drug policy to Artemisinin-based Combination Therapies (ACTs) for the treatment of malaria infection, and it is imperative for prescribers to strictly comply with this guideline to harmonize malaria management practices within the country. This study aims to evaluate prescribers’ adherence with the National Antimalarial Treatment Guideline (NATG) in the treatment of malaria infections and to describe the determinants of antimalarial drugs coprescription with antibiotics at a tertiary hospital in Nigeria. A cross-sectional, retrospective study of antimalarial drug prescriptions of one-year period of 2013 was conducted. A simple method for assessing the quality of drug prescribing (DU90%) was adopted. Logistic regression was used to predict antimalarial drugs coprescription with antibiotics. Overall, 95.8% of the total prescriptions contained ACTs, out of which 80.8% were Artemether/Lumefantrine. However, adherence to NATG was 88.2% with an adjusted value of 100.0%. Age was the only predictor for antimalarial drugs coprescription with antibiotics. This study showed high concordance with NATG at the studied hospital. Age less than 5 years is a significant risk factor for antimalarial drugs coprescription with antibiotics. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2018 1 6 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Roland Nnaemeka Okoro Muslim Olakunle Jamiu The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
In 2005, Nigeria changed its antimalarial drug policy to Artemisinin-based Combination Therapies (ACTs) for the treatment of malaria infection, and it is imperative for prescribers to strictly comply with this guideline to harmonize malaria management practices within the country. This study aims to evaluate prescribers’ adherence with the National Antimalarial Treatment Guideline (NATG) in the treatment of malaria infections and to describe the determinants of antimalarial drugs coprescription with antibiotics at a tertiary hospital in Nigeria. A cross-sectional, retrospective study of antimalarial drug prescriptions of one-year period of 2013 was conducted. A simple method for assessing the quality of drug prescribing (DU90%) was adopted. Logistic regression was used to predict antimalarial drugs coprescription with antibiotics. Overall, 95.8% of the total prescriptions contained ACTs, out of which 80.8% were Artemether/Lumefantrine. However, adherence to NATG was 88.2% with an adjusted value of 100.0%. Age was the only predictor for antimalarial drugs coprescription with antibiotics. This study showed high concordance with NATG at the studied hospital. Age less than 5 years is a significant risk factor for antimalarial drugs coprescription with antibiotics. |
format |
Article in Journal/Newspaper |
author |
Roland Nnaemeka Okoro Muslim Olakunle Jamiu |
author_facet |
Roland Nnaemeka Okoro Muslim Olakunle Jamiu |
author_sort |
Roland Nnaemeka Okoro |
title |
The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria |
title_short |
The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria |
title_full |
The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria |
title_fullStr |
The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria |
title_full_unstemmed |
The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria |
title_sort |
cross-sectional evaluation of the use of artemisinin-based combination therapy for treatment of malaria infection at a tertiary hospital in nigeria |
publisher |
Hindawi Limited |
publishDate |
2018 |
url |
https://doi.org/10.1155/2018/2025858 https://doaj.org/article/fb8406f5033c4cb9b927bc97c0302754 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2018 (2018) |
op_relation |
http://dx.doi.org/10.1155/2018/2025858 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2018/2025858 https://doaj.org/article/fb8406f5033c4cb9b927bc97c0302754 |
op_doi |
https://doi.org/10.1155/2018/2025858 |
container_title |
Journal of Tropical Medicine |
container_volume |
2018 |
container_start_page |
1 |
op_container_end_page |
6 |
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1766338073679888384 |