Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic
Abstract Background Lack of sustainable access to clean drinking water continues to be an issue of paramount global importance, leading to millions of preventable deaths annually. Best practices for providing sustainable access to clean drinking water, however, remain unclear. Widespread installatio...
Published in: | Tropical Medicine and Health |
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Online Access: | https://doi.org/10.1186/s41182-020-00291-y https://doaj.org/article/fac17e613607465583ab4f9bf805d5e2 |
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ftdoajarticles:oai:doaj.org/article:fac17e613607465583ab4f9bf805d5e2 2023-05-15T15:18:10+02:00 Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic Nathan Tintle Kristin Van De Griend Rachel Ulrich Randall D. Wade Tena M. Baar Emma Boven Carolyn E. A. Cooper Olivia Couch Lauren Eekhoff Benjamin Fry Grace K. Goszkowicz Maya A. Hecksel Adam Heynen Jade A. Laughlin Sydney M. Les Taylor R. Lombard B. Daniel Munson Jonas M. Peterson Eric Schumann Daniel J. Settecerri Jacob E. Spry Matthew J. Summerfield Meghana Sunder Daniel R. Wade Caden G. Zonnefeld Sarah A. Brokus Francesco S. Moen Adam D. Slater Jonathan W. Peterson Michael J. Pikaart Brent P. Krueger Aaron A. Best 2021-01-01T00:00:00Z https://doi.org/10.1186/s41182-020-00291-y https://doaj.org/article/fac17e613607465583ab4f9bf805d5e2 EN eng BMC https://doi.org/10.1186/s41182-020-00291-y https://doaj.org/toc/1349-4147 doi:10.1186/s41182-020-00291-y 1349-4147 https://doaj.org/article/fac17e613607465583ab4f9bf805d5e2 Tropical Medicine and Health, Vol 49, Iss 1, Pp 1-14 (2021) Drinking water Point-of-use filter 16S rRNA community Diarrhea Heavy metals Arctic medicine. Tropical medicine RC955-962 article 2021 ftdoajarticles https://doi.org/10.1186/s41182-020-00291-y 2022-12-31T06:44:15Z Abstract Background Lack of sustainable access to clean drinking water continues to be an issue of paramount global importance, leading to millions of preventable deaths annually. Best practices for providing sustainable access to clean drinking water, however, remain unclear. Widespread installation of low-cost, in-home, point of use water filtration systems is a promising strategy. Methods We conducted a prospective, randomized, controlled trial whereby 16 villages were selected and randomly assigned to one of four treatment arms based on the installation location of Sawyer® PointONE™ filters (filter in both home and school; filter in home only; filter in school only; control group). Water samples and self-reported information on diarrhea were collected at multiple times throughout the study. Results Self-reported household prevalence of diarrhea decreased from 25.6 to 9.76% from installation to follow-up (at least 7 days, and up to 200 days post-filter installation). These declines were also observed in diarrhea with economic or educational consequences (diarrhea which led to medical treatment and/or missing school or work) with baseline prevalence of 9.64% declining to 1.57%. Decreases in diarrhea prevalence were observed across age groups. There was no evidence of a loss of efficacy of filters up to 200 days post-filter installation. Installation of filters in schools was not associated with decreases in diarrhea prevalence in school-aged children or family members. Unfiltered water samples both at schools and homes contained potential waterborne bacterial pathogens, dissolved heavy metals and metals associated with particulates. All dissolved metals were detected at levels below World Health Organization action guidelines. Conclusions This controlled trial provides strong evidence of the effectiveness of point-of-use, hollow fiber membrane filters at reducing diarrhea from bacterial sources up to 200 days post-installation when installed in homes. No statistically significant reduction in diarrhea was ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Home Point ENVELOPE(-98.368,-98.368,72.951,72.951) Tropical Medicine and Health 49 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Drinking water Point-of-use filter 16S rRNA community Diarrhea Heavy metals Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Drinking water Point-of-use filter 16S rRNA community Diarrhea Heavy metals Arctic medicine. Tropical medicine RC955-962 Nathan Tintle Kristin Van De Griend Rachel Ulrich Randall D. Wade Tena M. Baar Emma Boven Carolyn E. A. Cooper Olivia Couch Lauren Eekhoff Benjamin Fry Grace K. Goszkowicz Maya A. Hecksel Adam Heynen Jade A. Laughlin Sydney M. Les Taylor R. Lombard B. Daniel Munson Jonas M. Peterson Eric Schumann Daniel J. Settecerri Jacob E. Spry Matthew J. Summerfield Meghana Sunder Daniel R. Wade Caden G. Zonnefeld Sarah A. Brokus Francesco S. Moen Adam D. Slater Jonathan W. Peterson Michael J. Pikaart Brent P. Krueger Aaron A. Best Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic |
topic_facet |
Drinking water Point-of-use filter 16S rRNA community Diarrhea Heavy metals Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Lack of sustainable access to clean drinking water continues to be an issue of paramount global importance, leading to millions of preventable deaths annually. Best practices for providing sustainable access to clean drinking water, however, remain unclear. Widespread installation of low-cost, in-home, point of use water filtration systems is a promising strategy. Methods We conducted a prospective, randomized, controlled trial whereby 16 villages were selected and randomly assigned to one of four treatment arms based on the installation location of Sawyer® PointONE™ filters (filter in both home and school; filter in home only; filter in school only; control group). Water samples and self-reported information on diarrhea were collected at multiple times throughout the study. Results Self-reported household prevalence of diarrhea decreased from 25.6 to 9.76% from installation to follow-up (at least 7 days, and up to 200 days post-filter installation). These declines were also observed in diarrhea with economic or educational consequences (diarrhea which led to medical treatment and/or missing school or work) with baseline prevalence of 9.64% declining to 1.57%. Decreases in diarrhea prevalence were observed across age groups. There was no evidence of a loss of efficacy of filters up to 200 days post-filter installation. Installation of filters in schools was not associated with decreases in diarrhea prevalence in school-aged children or family members. Unfiltered water samples both at schools and homes contained potential waterborne bacterial pathogens, dissolved heavy metals and metals associated with particulates. All dissolved metals were detected at levels below World Health Organization action guidelines. Conclusions This controlled trial provides strong evidence of the effectiveness of point-of-use, hollow fiber membrane filters at reducing diarrhea from bacterial sources up to 200 days post-installation when installed in homes. No statistically significant reduction in diarrhea was ... |
format |
Article in Journal/Newspaper |
author |
Nathan Tintle Kristin Van De Griend Rachel Ulrich Randall D. Wade Tena M. Baar Emma Boven Carolyn E. A. Cooper Olivia Couch Lauren Eekhoff Benjamin Fry Grace K. Goszkowicz Maya A. Hecksel Adam Heynen Jade A. Laughlin Sydney M. Les Taylor R. Lombard B. Daniel Munson Jonas M. Peterson Eric Schumann Daniel J. Settecerri Jacob E. Spry Matthew J. Summerfield Meghana Sunder Daniel R. Wade Caden G. Zonnefeld Sarah A. Brokus Francesco S. Moen Adam D. Slater Jonathan W. Peterson Michael J. Pikaart Brent P. Krueger Aaron A. Best |
author_facet |
Nathan Tintle Kristin Van De Griend Rachel Ulrich Randall D. Wade Tena M. Baar Emma Boven Carolyn E. A. Cooper Olivia Couch Lauren Eekhoff Benjamin Fry Grace K. Goszkowicz Maya A. Hecksel Adam Heynen Jade A. Laughlin Sydney M. Les Taylor R. Lombard B. Daniel Munson Jonas M. Peterson Eric Schumann Daniel J. Settecerri Jacob E. Spry Matthew J. Summerfield Meghana Sunder Daniel R. Wade Caden G. Zonnefeld Sarah A. Brokus Francesco S. Moen Adam D. Slater Jonathan W. Peterson Michael J. Pikaart Brent P. Krueger Aaron A. Best |
author_sort |
Nathan Tintle |
title |
Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic |
title_short |
Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic |
title_full |
Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic |
title_fullStr |
Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic |
title_full_unstemmed |
Diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the Dominican Republic |
title_sort |
diarrhea prevalence in a randomized, controlled prospective trial of point-of-use water filters in homes and schools in the dominican republic |
publisher |
BMC |
publishDate |
2021 |
url |
https://doi.org/10.1186/s41182-020-00291-y https://doaj.org/article/fac17e613607465583ab4f9bf805d5e2 |
long_lat |
ENVELOPE(-98.368,-98.368,72.951,72.951) |
geographic |
Arctic Home Point |
geographic_facet |
Arctic Home Point |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 49, Iss 1, Pp 1-14 (2021) |
op_relation |
https://doi.org/10.1186/s41182-020-00291-y https://doaj.org/toc/1349-4147 doi:10.1186/s41182-020-00291-y 1349-4147 https://doaj.org/article/fac17e613607465583ab4f9bf805d5e2 |
op_doi |
https://doi.org/10.1186/s41182-020-00291-y |
container_title |
Tropical Medicine and Health |
container_volume |
49 |
container_issue |
1 |
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1766348394728521728 |