Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1
Eutypenoids A–C (1–3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass s...
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2016
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Online Access: | https://doi.org/10.3390/md14030044 https://doaj.org/article/f998759c2b504e70b0a329651b5f421c |
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ftdoajarticles:oai:doaj.org/article:f998759c2b504e70b0a329651b5f421c 2023-05-15T14:40:48+02:00 Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 Liu-Qiang Zhang Xiao-Chong Chen Zhao-Qiang Chen Gui-Min Wang Shi-Guo Zhu Yi-Fu Yang Kai-Xian Chen Xiao-Yu Liu Yi-Ming Li 2016-03-01T00:00:00Z https://doi.org/10.3390/md14030044 https://doaj.org/article/f998759c2b504e70b0a329651b5f421c EN eng MDPI AG http://www.mdpi.com/1660-3397/14/3/44 https://doaj.org/toc/1660-3397 1660-3397 doi:10.3390/md14030044 https://doaj.org/article/f998759c2b504e70b0a329651b5f421c Marine Drugs, Vol 14, Iss 3, p 44 (2016) eutypenoid novel pimarane diterpenes Eutypella Arctic fungi immunosuppressive effect Biology (General) QH301-705.5 article 2016 ftdoajarticles https://doi.org/10.3390/md14030044 2022-12-30T22:39:53Z Eutypenoids A–C (1–3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass spectroscopy (MS), nuclear magnetic resonance (NMR), X-ray crystallography, and electronic circular dichroism (ECD) analysis. The immunosuppressive effects of eutypenoids A–C (1–3) were studied using a ConA-induced splenocyte proliferation model, which suggested that 2 exhibited potent immunosuppressive activities. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Marine Drugs 14 3 44 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
eutypenoid novel pimarane diterpenes Eutypella Arctic fungi immunosuppressive effect Biology (General) QH301-705.5 |
spellingShingle |
eutypenoid novel pimarane diterpenes Eutypella Arctic fungi immunosuppressive effect Biology (General) QH301-705.5 Liu-Qiang Zhang Xiao-Chong Chen Zhao-Qiang Chen Gui-Min Wang Shi-Guo Zhu Yi-Fu Yang Kai-Xian Chen Xiao-Yu Liu Yi-Ming Li Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 |
topic_facet |
eutypenoid novel pimarane diterpenes Eutypella Arctic fungi immunosuppressive effect Biology (General) QH301-705.5 |
description |
Eutypenoids A–C (1–3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass spectroscopy (MS), nuclear magnetic resonance (NMR), X-ray crystallography, and electronic circular dichroism (ECD) analysis. The immunosuppressive effects of eutypenoids A–C (1–3) were studied using a ConA-induced splenocyte proliferation model, which suggested that 2 exhibited potent immunosuppressive activities. |
format |
Article in Journal/Newspaper |
author |
Liu-Qiang Zhang Xiao-Chong Chen Zhao-Qiang Chen Gui-Min Wang Shi-Guo Zhu Yi-Fu Yang Kai-Xian Chen Xiao-Yu Liu Yi-Ming Li |
author_facet |
Liu-Qiang Zhang Xiao-Chong Chen Zhao-Qiang Chen Gui-Min Wang Shi-Guo Zhu Yi-Fu Yang Kai-Xian Chen Xiao-Yu Liu Yi-Ming Li |
author_sort |
Liu-Qiang Zhang |
title |
Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 |
title_short |
Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 |
title_full |
Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 |
title_fullStr |
Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 |
title_full_unstemmed |
Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1 |
title_sort |
eutypenoids a–c: novel pimarane diterpenoids from the arctic fungus eutypella sp. d-1 |
publisher |
MDPI AG |
publishDate |
2016 |
url |
https://doi.org/10.3390/md14030044 https://doaj.org/article/f998759c2b504e70b0a329651b5f421c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Marine Drugs, Vol 14, Iss 3, p 44 (2016) |
op_relation |
http://www.mdpi.com/1660-3397/14/3/44 https://doaj.org/toc/1660-3397 1660-3397 doi:10.3390/md14030044 https://doaj.org/article/f998759c2b504e70b0a329651b5f421c |
op_doi |
https://doi.org/10.3390/md14030044 |
container_title |
Marine Drugs |
container_volume |
14 |
container_issue |
3 |
container_start_page |
44 |
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1766312673449869312 |