Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study
Abstract Background Raynaud’s phenomenon is common condition, but little is known about the natural course. The primary aim of this study was to determine the incidence, remission, and persistence proportions of Raynaud’s phenomenon in the general population of northern Sweden. Secondary aims were t...
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ftdoajarticles:oai:doaj.org/article:f98330b3c5c8477dbec567f0f7dad271 2023-05-15T17:44:18+02:00 Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study Albin Stjernbrandt Hans Pettersson Ronnie Lundström Ingrid Liljelind Tohr Nilsson Jens Wahlström 2022-07-01T00:00:00Z https://doi.org/10.1186/s41927-022-00272-0 https://doaj.org/article/f98330b3c5c8477dbec567f0f7dad271 EN eng BMC https://doi.org/10.1186/s41927-022-00272-0 https://doaj.org/toc/2520-1026 doi:10.1186/s41927-022-00272-0 2520-1026 https://doaj.org/article/f98330b3c5c8477dbec567f0f7dad271 BMC Rheumatology, Vol 6, Iss 1, Pp 1-10 (2022) Sweden Longitudinal studies Raynaud disease Incidence Remission Spontaneous Occupational exposure Diseases of the musculoskeletal system RC925-935 article 2022 ftdoajarticles https://doi.org/10.1186/s41927-022-00272-0 2022-12-31T02:23:30Z Abstract Background Raynaud’s phenomenon is common condition, but little is known about the natural course. The primary aim of this study was to determine the incidence, remission, and persistence proportions of Raynaud’s phenomenon in the general population of northern Sweden. Secondary aims were to determine how individual and exposure factors affect the course of Raynaud’s phenomenon, and to assess gender differences. Methods A prospective, survey-based, closed-cohort study was conducted on a sample of men and women between 18–70 years of age, living in northern Sweden. Data on Raynaud’s phenomenon characteristics and general health status were collected during the winters of 2015 (baseline) and 2021 (follow-up). Rates of incidence, remission, and persistence were calculated. Binary logistic regression was used to determine the association between baseline variables and the course of Raynaud’s phenomenon. Results: The study population consisted of 2703 women (53.9%) and 2314 men. There were 390 women (14.5%) and 290 men (12.7%) reporting Raynaud’s phenomenon in the follow-up survey. The annual incidence proportion was 0.7% among women and 0.9% among men (gender difference p = 0.04). The annual remission proportion was 4.4% and 5.5%, respectively (p = 0.05). Having sustained a cold injury affecting the hands since baseline was significantly associated with incident Raynaud’s phenomenon (OR 3.92; 95% CI 2.60–5.90), after adjusting for age and gender. Conclusions In the general population of northern Sweden, Raynaud’s phenomenon is a common but variable condition, where symptoms may remit over time. Men had a higher incidence proportion than women. The results support a possible causal pathway where cold injury can precede the onset of Raynaud’s phenomenon. Article in Journal/Newspaper Northern Sweden Directory of Open Access Journals: DOAJ Articles BMC Rheumatology 6 1 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Sweden Longitudinal studies Raynaud disease Incidence Remission Spontaneous Occupational exposure Diseases of the musculoskeletal system RC925-935 |
spellingShingle |
Sweden Longitudinal studies Raynaud disease Incidence Remission Spontaneous Occupational exposure Diseases of the musculoskeletal system RC925-935 Albin Stjernbrandt Hans Pettersson Ronnie Lundström Ingrid Liljelind Tohr Nilsson Jens Wahlström Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study |
topic_facet |
Sweden Longitudinal studies Raynaud disease Incidence Remission Spontaneous Occupational exposure Diseases of the musculoskeletal system RC925-935 |
description |
Abstract Background Raynaud’s phenomenon is common condition, but little is known about the natural course. The primary aim of this study was to determine the incidence, remission, and persistence proportions of Raynaud’s phenomenon in the general population of northern Sweden. Secondary aims were to determine how individual and exposure factors affect the course of Raynaud’s phenomenon, and to assess gender differences. Methods A prospective, survey-based, closed-cohort study was conducted on a sample of men and women between 18–70 years of age, living in northern Sweden. Data on Raynaud’s phenomenon characteristics and general health status were collected during the winters of 2015 (baseline) and 2021 (follow-up). Rates of incidence, remission, and persistence were calculated. Binary logistic regression was used to determine the association between baseline variables and the course of Raynaud’s phenomenon. Results: The study population consisted of 2703 women (53.9%) and 2314 men. There were 390 women (14.5%) and 290 men (12.7%) reporting Raynaud’s phenomenon in the follow-up survey. The annual incidence proportion was 0.7% among women and 0.9% among men (gender difference p = 0.04). The annual remission proportion was 4.4% and 5.5%, respectively (p = 0.05). Having sustained a cold injury affecting the hands since baseline was significantly associated with incident Raynaud’s phenomenon (OR 3.92; 95% CI 2.60–5.90), after adjusting for age and gender. Conclusions In the general population of northern Sweden, Raynaud’s phenomenon is a common but variable condition, where symptoms may remit over time. Men had a higher incidence proportion than women. The results support a possible causal pathway where cold injury can precede the onset of Raynaud’s phenomenon. |
format |
Article in Journal/Newspaper |
author |
Albin Stjernbrandt Hans Pettersson Ronnie Lundström Ingrid Liljelind Tohr Nilsson Jens Wahlström |
author_facet |
Albin Stjernbrandt Hans Pettersson Ronnie Lundström Ingrid Liljelind Tohr Nilsson Jens Wahlström |
author_sort |
Albin Stjernbrandt |
title |
Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study |
title_short |
Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study |
title_full |
Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study |
title_fullStr |
Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study |
title_full_unstemmed |
Incidence, remission, and persistence of Raynaud’s phenomenon in the general population of northern Sweden: a prospective study |
title_sort |
incidence, remission, and persistence of raynaud’s phenomenon in the general population of northern sweden: a prospective study |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s41927-022-00272-0 https://doaj.org/article/f98330b3c5c8477dbec567f0f7dad271 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
BMC Rheumatology, Vol 6, Iss 1, Pp 1-10 (2022) |
op_relation |
https://doi.org/10.1186/s41927-022-00272-0 https://doaj.org/toc/2520-1026 doi:10.1186/s41927-022-00272-0 2520-1026 https://doaj.org/article/f98330b3c5c8477dbec567f0f7dad271 |
op_doi |
https://doi.org/10.1186/s41927-022-00272-0 |
container_title |
BMC Rheumatology |
container_volume |
6 |
container_issue |
1 |
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1766146512694280192 |