Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases
O estudo epidemiológico e neuropatológico concernente a trinta autópsias de encefalite rábica foi realizado, tendo sido os dados obtidos comparados com aqueles da literatura. Não houve relação estatística entre a topografia lesional e o local da mordida, entre o período de incubação ou a duração da...
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ftdoajarticles:oai:doaj.org/article:f889ca85bd15453cb99cbd97891d63ae 2024-09-09T19:27:04+00:00 Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases R. V. C. Assis S. Rosemberg 1984-12-01T00:00:00Z https://doaj.org/article/f889ca85bd15453cb99cbd97891d63ae EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651984000600010 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 0036-4665 1678-9946 https://doaj.org/article/f889ca85bd15453cb99cbd97891d63ae Revista do Instituto de Medicina Tropical de São Paulo, Vol 26, Iss 6, Pp 346-352 (1984) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1984 ftdoajarticles 2024-08-05T17:49:31Z O estudo epidemiológico e neuropatológico concernente a trinta autópsias de encefalite rábica foi realizado, tendo sido os dados obtidos comparados com aqueles da literatura. Não houve relação estatística entre a topografia lesional e o local da mordida, entre o período de incubação ou a duração da doença e a presença ou ausência de inclusões virais (IV) assim como entre a intensidade do processo inflamatorio (PI) e a presença de IV. A dispersão do PI e das IV através o SNC foi diretamente proporcional à sua intensidade. A estrutura mais freqüentemente comprometida pelo PI foi o mesencéfalo, seguido pelo bulbo, ponte e medula espinhal. A estrutura mais intensamente afetada foi o bulbo. As IV foram particularmente proeminentes no hipocampo e cerebelo. Thirty autopsies of human rabies encephalitis were carried out and the results of some epidemiological data and neuropathological studies were compared with those previously reported. There was no statistical relation between the topography of the lesions and the site of bite, between the incubation period or disease duration and the presence or absence of viral inclusion bodies (VIB), and between the intensity of the inflammatory process (IP) and the presence of VIB. The dispersion of the IP and of the VIB throughout the CNS was in direct proportion to their intensity. The most frequently affected structure by the IP was the midbrain, followed by the medulla oblongata, pons and spinal cord. The most intensively injured structure was the medulla oblangata. The VIB had striking predominance in the hippocampus and cerebellum. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 R. V. C. Assis S. Rosemberg Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
O estudo epidemiológico e neuropatológico concernente a trinta autópsias de encefalite rábica foi realizado, tendo sido os dados obtidos comparados com aqueles da literatura. Não houve relação estatística entre a topografia lesional e o local da mordida, entre o período de incubação ou a duração da doença e a presença ou ausência de inclusões virais (IV) assim como entre a intensidade do processo inflamatorio (PI) e a presença de IV. A dispersão do PI e das IV através o SNC foi diretamente proporcional à sua intensidade. A estrutura mais freqüentemente comprometida pelo PI foi o mesencéfalo, seguido pelo bulbo, ponte e medula espinhal. A estrutura mais intensamente afetada foi o bulbo. As IV foram particularmente proeminentes no hipocampo e cerebelo. Thirty autopsies of human rabies encephalitis were carried out and the results of some epidemiological data and neuropathological studies were compared with those previously reported. There was no statistical relation between the topography of the lesions and the site of bite, between the incubation period or disease duration and the presence or absence of viral inclusion bodies (VIB), and between the intensity of the inflammatory process (IP) and the presence of VIB. The dispersion of the IP and of the VIB throughout the CNS was in direct proportion to their intensity. The most frequently affected structure by the IP was the midbrain, followed by the medulla oblongata, pons and spinal cord. The most intensively injured structure was the medulla oblangata. The VIB had striking predominance in the hippocampus and cerebellum. |
format |
Article in Journal/Newspaper |
author |
R. V. C. Assis S. Rosemberg |
author_facet |
R. V. C. Assis S. Rosemberg |
author_sort |
R. V. C. Assis |
title |
Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases |
title_short |
Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases |
title_full |
Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases |
title_fullStr |
Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases |
title_full_unstemmed |
Raiva humana: estudo neuropatológico de trinta casos Human rabies: neuropathological study of thirty cases |
title_sort |
raiva humana: estudo neuropatológico de trinta casos human rabies: neuropathological study of thirty cases |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1984 |
url |
https://doaj.org/article/f889ca85bd15453cb99cbd97891d63ae |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 26, Iss 6, Pp 346-352 (1984) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651984000600010 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 0036-4665 1678-9946 https://doaj.org/article/f889ca85bd15453cb99cbd97891d63ae |
_version_ |
1809896565152677888 |