An aspartic protease of the scabies mite Sarcoptes scabiei is involved in the digestion of host skin and blood macromolecules.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Wajahat Mahmood, Linda T Viberg, Katja Fischer, Shelley F Walton, Deborah C Holt
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2013
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Burrows; Mite
• Online Access: https://doi.org/10.1371/journal.pntd.0002525; https://doaj.org/article/f81b6c3ce3cc4584a68973e92f4a4f45

BACKGROUND: Scabies is a disease of worldwide significance, causing considerable morbidity in both humans and other animals. The scabies mite Sarcoptes scabiei burrows into the skin of its host, obtaining nutrition from host skin and blood. Aspartic proteases mediate a range of diverse and essential...