The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria
Objective: To investigate the effect of Iranian honey, cinnamon and their combination against Streptococcus mutans bacteria. Methods: Nine experimental solutions were examined in this study, including two types of honey (pasteurized and sterilized), two types of cinnamon extract (dissolved in distil...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
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ftdoajarticles:oai:doaj.org/article:f7c6984479694ce9a9ea5d8121a165f4 2023-05-15T15:12:29+02:00 The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria Mohammad Bagher Rezvani Mohammad Niakan Mohammad Kamalinejad Fateme Sadat Ahmadi Faeze Hamze 2017-04-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.11.029 https://doaj.org/article/f7c6984479694ce9a9ea5d8121a165f4 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117300400 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.11.029 https://doaj.org/article/f7c6984479694ce9a9ea5d8121a165f4 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 4, Pp 314-320 (2017) Synergistic effect Honey Cinnamon Streptococcus mutans Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.11.029 2022-12-31T03:32:24Z Objective: To investigate the effect of Iranian honey, cinnamon and their combination against Streptococcus mutans bacteria. Methods: Nine experimental solutions were examined in this study, including two types of honey (pasteurized and sterilized), two types of cinnamon extract (dissolved in distilled water or dimethyl sulfoxide) and five different mixtures of cinnamon in honey (prepared by admixing 1%–5% w/w of cinnamon extract into 99%–95% w/w of honey, respectively). Meanwhile, each of mentioned agent was considered as the first solution while it was diluted into seven serially two-fold dilutions (from 1:2 to 1:128 v/v). Therefore, eight different concentrations of each agent were tested. The antibacterial tests were performed through blood agar well diffusion method, and the minimum inhibitory concentration (MIC) was determined. Ultimately, the data were subjected to statistical analysis incorporating Two-way ANOVA and Bonferroni post hoc tests (α = 0.01). Results: The highest zone of inhibition was recorded for the mixtures of honey and cinnamon while all the subgroups containing 95%–99% v/v of honey were in the same range (P < 0.01). The MIC for both honey solutions were obtained as 500 mg/mL whereas it was 50 mg/mL for both cinnamon solutions. Moreover, the MIC related to all honey/cinnamon mixtures were 200 mg/mL. Conclusions: A profound synergistic effect of honey and cinnamon was observed against Streptococcus mutans while there was no significant difference among extracts containing 99%–95% v/v of honey admixing with 1%–5% v/v of cinnamon, respectively. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 4 314 320 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Synergistic effect Honey Cinnamon Streptococcus mutans Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Synergistic effect Honey Cinnamon Streptococcus mutans Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Mohammad Bagher Rezvani Mohammad Niakan Mohammad Kamalinejad Fateme Sadat Ahmadi Faeze Hamze The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria |
topic_facet |
Synergistic effect Honey Cinnamon Streptococcus mutans Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To investigate the effect of Iranian honey, cinnamon and their combination against Streptococcus mutans bacteria. Methods: Nine experimental solutions were examined in this study, including two types of honey (pasteurized and sterilized), two types of cinnamon extract (dissolved in distilled water or dimethyl sulfoxide) and five different mixtures of cinnamon in honey (prepared by admixing 1%–5% w/w of cinnamon extract into 99%–95% w/w of honey, respectively). Meanwhile, each of mentioned agent was considered as the first solution while it was diluted into seven serially two-fold dilutions (from 1:2 to 1:128 v/v). Therefore, eight different concentrations of each agent were tested. The antibacterial tests were performed through blood agar well diffusion method, and the minimum inhibitory concentration (MIC) was determined. Ultimately, the data were subjected to statistical analysis incorporating Two-way ANOVA and Bonferroni post hoc tests (α = 0.01). Results: The highest zone of inhibition was recorded for the mixtures of honey and cinnamon while all the subgroups containing 95%–99% v/v of honey were in the same range (P < 0.01). The MIC for both honey solutions were obtained as 500 mg/mL whereas it was 50 mg/mL for both cinnamon solutions. Moreover, the MIC related to all honey/cinnamon mixtures were 200 mg/mL. Conclusions: A profound synergistic effect of honey and cinnamon was observed against Streptococcus mutans while there was no significant difference among extracts containing 99%–95% v/v of honey admixing with 1%–5% v/v of cinnamon, respectively. |
format |
Article in Journal/Newspaper |
author |
Mohammad Bagher Rezvani Mohammad Niakan Mohammad Kamalinejad Fateme Sadat Ahmadi Faeze Hamze |
author_facet |
Mohammad Bagher Rezvani Mohammad Niakan Mohammad Kamalinejad Fateme Sadat Ahmadi Faeze Hamze |
author_sort |
Mohammad Bagher Rezvani |
title |
The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria |
title_short |
The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria |
title_full |
The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria |
title_fullStr |
The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria |
title_full_unstemmed |
The synergistic effect of honey and cinnamon against Streptococcus mutans bacteria |
title_sort |
synergistic effect of honey and cinnamon against streptococcus mutans bacteria |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2016.11.029 https://doaj.org/article/f7c6984479694ce9a9ea5d8121a165f4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 4, Pp 314-320 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117300400 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.11.029 https://doaj.org/article/f7c6984479694ce9a9ea5d8121a165f4 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.11.029 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
4 |
container_start_page |
314 |
op_container_end_page |
320 |
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1766343155897073664 |