Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study
HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria....
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ftdoajarticles:oai:doaj.org/article:f78afdf2996f427f943edaf30a56528f 2023-05-15T18:34:23+02:00 Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde 2013-01-01T00:00:00Z https://doi.org/10.1155/2013/613475 https://doaj.org/article/f78afdf2996f427f943edaf30a56528f EN eng Hindawi Limited http://dx.doi.org/10.1155/2013/613475 https://doaj.org/toc/1687-8337 https://doaj.org/toc/1687-8345 1687-8337 1687-8345 doi:10.1155/2013/613475 https://doaj.org/article/f78afdf2996f427f943edaf30a56528f International Journal of Endocrinology, Vol 2013 (2013) Diseases of the endocrine glands. Clinical endocrinology RC648-665 article 2013 ftdoajarticles https://doi.org/10.1155/2013/613475 2022-12-31T01:54:36Z HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria. Subjects were recruited among participants in the longitudinal population-based Tromsø Study. HbA1c, fasting plasma glucose, and 2-hour plasma glucose were measured in 3,476 subjects. In total, 294 subjects met one or more of the diagnostic criteria for diabetes; 95 met the HbA1c criterion only, 130 met the glucose criteria only, and 69 met both. Among subjects with diabetes detected by glucose criteria (regardless of HbA1c), isolated raised 2-hour plasma glucose was more common in subjects aged ≥ 60 years as compared to younger subjects and in elderly women as compared to elderly men. Subjects with diabetes detected by glucose criteria only had worse cardiometabolic risk profiles than those detected by HbA1c only. In conclusion, the current HbA1c and glucose criteria defined different subjects with diabetes with only modest overlap. Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value. Article in Journal/Newspaper Tromsø Directory of Open Access Journals: DOAJ Articles Tromsø International Journal of Endocrinology 2013 1 9 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
spellingShingle |
Diseases of the endocrine glands. Clinical endocrinology RC648-665 Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
topic_facet |
Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
description |
HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria. Subjects were recruited among participants in the longitudinal population-based Tromsø Study. HbA1c, fasting plasma glucose, and 2-hour plasma glucose were measured in 3,476 subjects. In total, 294 subjects met one or more of the diagnostic criteria for diabetes; 95 met the HbA1c criterion only, 130 met the glucose criteria only, and 69 met both. Among subjects with diabetes detected by glucose criteria (regardless of HbA1c), isolated raised 2-hour plasma glucose was more common in subjects aged ≥ 60 years as compared to younger subjects and in elderly women as compared to elderly men. Subjects with diabetes detected by glucose criteria only had worse cardiometabolic risk profiles than those detected by HbA1c only. In conclusion, the current HbA1c and glucose criteria defined different subjects with diabetes with only modest overlap. Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value. |
format |
Article in Journal/Newspaper |
author |
Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde |
author_facet |
Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde |
author_sort |
Moira Strand Hutchinson |
title |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_short |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_full |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_fullStr |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_full_unstemmed |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_sort |
effects of age and sex on estimated diabetes prevalence using different diagnostic criteria: the tromsø ogtt study |
publisher |
Hindawi Limited |
publishDate |
2013 |
url |
https://doi.org/10.1155/2013/613475 https://doaj.org/article/f78afdf2996f427f943edaf30a56528f |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
International Journal of Endocrinology, Vol 2013 (2013) |
op_relation |
http://dx.doi.org/10.1155/2013/613475 https://doaj.org/toc/1687-8337 https://doaj.org/toc/1687-8345 1687-8337 1687-8345 doi:10.1155/2013/613475 https://doaj.org/article/f78afdf2996f427f943edaf30a56528f |
op_doi |
https://doi.org/10.1155/2013/613475 |
container_title |
International Journal of Endocrinology |
container_volume |
2013 |
container_start_page |
1 |
op_container_end_page |
9 |
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1766219107945938944 |