The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil

Abstract INTRODUCTION The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied. METHODS A descriptive study of adolescents with suspected tuberculosis using National Laboratory so...

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Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Thania Luiza de Andrade Sieiro, Rafaela Baroni Aurílio, Elizabeth Cristina C. Soares, Silvia S. Chiang, Clemax Couto Sant´Anna
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Subjects:
Rif
Online Access:https://doi.org/10.1590/0037-8682-0298-2017
https://doaj.org/article/f779b7b8899d4aa99b4cf05323d67d68
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spelling ftdoajarticles:oai:doaj.org/article:f779b7b8899d4aa99b4cf05323d67d68 2023-05-15T15:01:34+02:00 The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil Thania Luiza de Andrade Sieiro Rafaela Baroni Aurílio Elizabeth Cristina C. Soares Silvia S. Chiang Clemax Couto Sant´Anna https://doi.org/10.1590/0037-8682-0298-2017 https://doaj.org/article/f779b7b8899d4aa99b4cf05323d67d68 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200234&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0298-2017 https://doaj.org/article/f779b7b8899d4aa99b4cf05323d67d68 Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 2, Pp 234-236 Tuberculosis Adolescents Polymerase chain reaction Arctic medicine. Tropical medicine RC955-962 article ftdoajarticles https://doi.org/10.1590/0037-8682-0298-2017 2022-12-31T02:02:16Z Abstract INTRODUCTION The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied. METHODS A descriptive study of adolescents with suspected tuberculosis using National Laboratory software. RESULTS Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST). CONCLUSIONS Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Rif ENVELOPE(-16.172,-16.172,66.526,66.526) Revista da Sociedade Brasileira de Medicina Tropical 51 2 234 236
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Tuberculosis
Adolescents
Polymerase chain reaction
Arctic medicine. Tropical medicine
RC955-962
spellingShingle Tuberculosis
Adolescents
Polymerase chain reaction
Arctic medicine. Tropical medicine
RC955-962
Thania Luiza de Andrade Sieiro
Rafaela Baroni Aurílio
Elizabeth Cristina C. Soares
Silvia S. Chiang
Clemax Couto Sant´Anna
The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil
topic_facet Tuberculosis
Adolescents
Polymerase chain reaction
Arctic medicine. Tropical medicine
RC955-962
description Abstract INTRODUCTION The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied. METHODS A descriptive study of adolescents with suspected tuberculosis using National Laboratory software. RESULTS Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST). CONCLUSIONS Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST.
format Article in Journal/Newspaper
author Thania Luiza de Andrade Sieiro
Rafaela Baroni Aurílio
Elizabeth Cristina C. Soares
Silvia S. Chiang
Clemax Couto Sant´Anna
author_facet Thania Luiza de Andrade Sieiro
Rafaela Baroni Aurílio
Elizabeth Cristina C. Soares
Silvia S. Chiang
Clemax Couto Sant´Anna
author_sort Thania Luiza de Andrade Sieiro
title The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil
title_short The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil
title_full The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil
title_fullStr The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil
title_full_unstemmed The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil
title_sort role of the xpert mtb/rif assay among adolescents suspected of pulmonary tuberculosis in rio de janeiro, brazil
publisher Sociedade Brasileira de Medicina Tropical (SBMT)
url https://doi.org/10.1590/0037-8682-0298-2017
https://doaj.org/article/f779b7b8899d4aa99b4cf05323d67d68
long_lat ENVELOPE(-16.172,-16.172,66.526,66.526)
geographic Arctic
Rif
geographic_facet Arctic
Rif
genre Arctic
genre_facet Arctic
op_source Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 2, Pp 234-236
op_relation http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200234&lng=en&tlng=en
https://doaj.org/toc/1678-9849
1678-9849
doi:10.1590/0037-8682-0298-2017
https://doaj.org/article/f779b7b8899d4aa99b4cf05323d67d68
op_doi https://doi.org/10.1590/0037-8682-0298-2017
container_title Revista da Sociedade Brasileira de Medicina Tropical
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