Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review.
Tuberculosis (TB) is one of the most devastating infectious diseases worldwide. Whilst global burden estimates for M. tuberculosis infection (MtTB) are well established, accurate data on the contribution of zoonotic TB (zTB) caused by M. bovis or M. caprae to human TB are scarce. The association of...
Published in: | PLoS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0002399 https://doaj.org/article/f74ec4adbedb4ad9823cd70abc50ed81 |
id |
ftdoajarticles:oai:doaj.org/article:f74ec4adbedb4ad9823cd70abc50ed81 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:f74ec4adbedb4ad9823cd70abc50ed81 2023-05-15T15:12:25+02:00 Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. Salome Dürr Borna Müller Silvia Alonso Jan Hattendorf Cláudio J M Laisse Paul D van Helden Jakob Zinsstag 2013-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002399 https://doaj.org/article/f74ec4adbedb4ad9823cd70abc50ed81 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3757065?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002399 https://doaj.org/article/f74ec4adbedb4ad9823cd70abc50ed81 PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2399 (2013) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002399 2023-01-08T01:28:20Z Tuberculosis (TB) is one of the most devastating infectious diseases worldwide. Whilst global burden estimates for M. tuberculosis infection (MtTB) are well established, accurate data on the contribution of zoonotic TB (zTB) caused by M. bovis or M. caprae to human TB are scarce. The association of M. bovis infection with extrapulmonary tuberculosis has been suggested repeatedly, though there is little scientific evidence available to support this relationship. The present study aimed to determine globally the occurrence of extrapulmonary TB and the primary site (i.e. primary body location affected) of zTB in comparison with MtTB, based on previously published reports. A systematic literature review was conducted in 32 different bibliographic databases, selecting reports on zTB written in English, French, German, Spanish or Portuguese. Data from 27 reports from Africa, America, Europe and the Western Pacific Region were extracted for analyses. Low income countries, in Africa and South-East Asia, were highly underrepresented in the dataset. The median proportion of extrapulmonary TB cases was significantly increased among zTB in comparison with data from registries of Europe and USA, reporting mainly MtTB cases (47% versus 22% in Europe, 73% versus 30% in the USA). These findings were confirmed by analyses of eight studies reporting on the proportions of extrapulmonary TB in comparable populations of zTB and MtTB cases (median 63% versus 22%). Also, disparities of primary sites of extrapulmonary TB between zTB and MtTB were detected. Our findings, based on global data, confirm the widely suggested association between zTB and extrapulmonary disease. Different disability weights for zTB and MtTB should be considered and we recommend separate burden estimates for the two diseases. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pacific PLoS Neglected Tropical Diseases 7 8 e2399 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Salome Dürr Borna Müller Silvia Alonso Jan Hattendorf Cláudio J M Laisse Paul D van Helden Jakob Zinsstag Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Tuberculosis (TB) is one of the most devastating infectious diseases worldwide. Whilst global burden estimates for M. tuberculosis infection (MtTB) are well established, accurate data on the contribution of zoonotic TB (zTB) caused by M. bovis or M. caprae to human TB are scarce. The association of M. bovis infection with extrapulmonary tuberculosis has been suggested repeatedly, though there is little scientific evidence available to support this relationship. The present study aimed to determine globally the occurrence of extrapulmonary TB and the primary site (i.e. primary body location affected) of zTB in comparison with MtTB, based on previously published reports. A systematic literature review was conducted in 32 different bibliographic databases, selecting reports on zTB written in English, French, German, Spanish or Portuguese. Data from 27 reports from Africa, America, Europe and the Western Pacific Region were extracted for analyses. Low income countries, in Africa and South-East Asia, were highly underrepresented in the dataset. The median proportion of extrapulmonary TB cases was significantly increased among zTB in comparison with data from registries of Europe and USA, reporting mainly MtTB cases (47% versus 22% in Europe, 73% versus 30% in the USA). These findings were confirmed by analyses of eight studies reporting on the proportions of extrapulmonary TB in comparable populations of zTB and MtTB cases (median 63% versus 22%). Also, disparities of primary sites of extrapulmonary TB between zTB and MtTB were detected. Our findings, based on global data, confirm the widely suggested association between zTB and extrapulmonary disease. Different disability weights for zTB and MtTB should be considered and we recommend separate burden estimates for the two diseases. |
format |
Article in Journal/Newspaper |
author |
Salome Dürr Borna Müller Silvia Alonso Jan Hattendorf Cláudio J M Laisse Paul D van Helden Jakob Zinsstag |
author_facet |
Salome Dürr Borna Müller Silvia Alonso Jan Hattendorf Cláudio J M Laisse Paul D van Helden Jakob Zinsstag |
author_sort |
Salome Dürr |
title |
Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
title_short |
Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
title_full |
Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
title_fullStr |
Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
title_full_unstemmed |
Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
title_sort |
differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2013 |
url |
https://doi.org/10.1371/journal.pntd.0002399 https://doaj.org/article/f74ec4adbedb4ad9823cd70abc50ed81 |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2399 (2013) |
op_relation |
http://europepmc.org/articles/PMC3757065?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002399 https://doaj.org/article/f74ec4adbedb4ad9823cd70abc50ed81 |
op_doi |
https://doi.org/10.1371/journal.pntd.0002399 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
7 |
container_issue |
8 |
container_start_page |
e2399 |
_version_ |
1766343103461982208 |