Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study
Background. The present study explores the influence of the host’s age and gender upon the inflammatory infiltrate. We aimed to quantify the inflammatory infiltrate caused by cysticercosis, which is related to aging, in the heart and in the encephalon. Methods. 75 autopsy protocols with cysticercosi...
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ftdoajarticles:oai:doaj.org/article:f6c1ce6c77fb4e4b950328ab8afc2abb 2024-09-09T19:26:13+00:00 Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study Camila Lourencini Cavellani Rosana Rosa Miranda Corrêa Mara Lúcia Fonseca Ferraz Laura Penna Rocha Ana Carolina Guimarães Faleiros Ruy de Souza Lino Junior Marlene Antônia dos Reis Vicente de Paula Antunes Teixeira 2012-01-01T00:00:00Z https://doi.org/10.1155/2012/540858 https://doaj.org/article/f6c1ce6c77fb4e4b950328ab8afc2abb EN eng Wiley http://dx.doi.org/10.1155/2012/540858 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2012/540858 https://doaj.org/article/f6c1ce6c77fb4e4b950328ab8afc2abb Journal of Tropical Medicine, Vol 2012 (2012) Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles https://doi.org/10.1155/2012/540858 2024-08-05T17:48:41Z Background. The present study explores the influence of the host’s age and gender upon the inflammatory infiltrate. We aimed to quantify the inflammatory infiltrate caused by cysticercosis, which is related to aging, in the heart and in the encephalon. Methods. 75 autopsy protocols with cysticercosis diagnosis from department of pathology at a university hospital from 1970 to 2008 were reviewed. Two groups were formed: elderly with cysticercosis and nonelderly with cysticercosis. We used KS-300 (Kontron-Zeiss) software for morphometric analysis of the inflammation. Results. The elderly had an average of 3.1±2.5 cysticerci, whereas the non-elderly had 2.7±3.8 parasites. The non-elderly group with cysticercosis had significantly more inflammation, both cardiac and encephalic, than the elderly group. The elderly females with cysticercosis had more cardiac and encephalic inflammation. Conclusions. In this study, we showed that the non-elderly had significantly more cardiac and encephalic inflammation than the elderly, and that such inflammatory infiltrate decreases with age and depends upon the evolutionary stage of the cysticercus. Furthermore, there are differences concerning gender in the intensity of the inflammatory response due to cysticerci in the heart and brain parenchyma during senescence. Even during this period, women continue to have a more intense response to the parasitosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2012 1 6 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Camila Lourencini Cavellani Rosana Rosa Miranda Corrêa Mara Lúcia Fonseca Ferraz Laura Penna Rocha Ana Carolina Guimarães Faleiros Ruy de Souza Lino Junior Marlene Antônia dos Reis Vicente de Paula Antunes Teixeira Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Background. The present study explores the influence of the host’s age and gender upon the inflammatory infiltrate. We aimed to quantify the inflammatory infiltrate caused by cysticercosis, which is related to aging, in the heart and in the encephalon. Methods. 75 autopsy protocols with cysticercosis diagnosis from department of pathology at a university hospital from 1970 to 2008 were reviewed. Two groups were formed: elderly with cysticercosis and nonelderly with cysticercosis. We used KS-300 (Kontron-Zeiss) software for morphometric analysis of the inflammation. Results. The elderly had an average of 3.1±2.5 cysticerci, whereas the non-elderly had 2.7±3.8 parasites. The non-elderly group with cysticercosis had significantly more inflammation, both cardiac and encephalic, than the elderly group. The elderly females with cysticercosis had more cardiac and encephalic inflammation. Conclusions. In this study, we showed that the non-elderly had significantly more cardiac and encephalic inflammation than the elderly, and that such inflammatory infiltrate decreases with age and depends upon the evolutionary stage of the cysticercus. Furthermore, there are differences concerning gender in the intensity of the inflammatory response due to cysticerci in the heart and brain parenchyma during senescence. Even during this period, women continue to have a more intense response to the parasitosis. |
format |
Article in Journal/Newspaper |
author |
Camila Lourencini Cavellani Rosana Rosa Miranda Corrêa Mara Lúcia Fonseca Ferraz Laura Penna Rocha Ana Carolina Guimarães Faleiros Ruy de Souza Lino Junior Marlene Antônia dos Reis Vicente de Paula Antunes Teixeira |
author_facet |
Camila Lourencini Cavellani Rosana Rosa Miranda Corrêa Mara Lúcia Fonseca Ferraz Laura Penna Rocha Ana Carolina Guimarães Faleiros Ruy de Souza Lino Junior Marlene Antônia dos Reis Vicente de Paula Antunes Teixeira |
author_sort |
Camila Lourencini Cavellani |
title |
Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study |
title_short |
Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study |
title_full |
Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study |
title_fullStr |
Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study |
title_full_unstemmed |
Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study |
title_sort |
influence of gender on cardiac and encephalic inflammation in the elderly with cysticercosis: a case control study |
publisher |
Wiley |
publishDate |
2012 |
url |
https://doi.org/10.1155/2012/540858 https://doaj.org/article/f6c1ce6c77fb4e4b950328ab8afc2abb |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2012 (2012) |
op_relation |
http://dx.doi.org/10.1155/2012/540858 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2012/540858 https://doaj.org/article/f6c1ce6c77fb4e4b950328ab8afc2abb |
op_doi |
https://doi.org/10.1155/2012/540858 |
container_title |
Journal of Tropical Medicine |
container_volume |
2012 |
container_start_page |
1 |
op_container_end_page |
6 |
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1809895874624487424 |