Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals
Abstract INTRODUCTION: The prevalence of low bone mass is 3 times higher in people living with human immunodeficiency virus (PLWH) and using antiretrovirals than in the HIV-unaffected population. Changes in vitamin D levels is one of the factors associated with decreased bone mass. The objective of...
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ftdoajarticles:oai:doaj.org/article:f62916e58b31488faad39a4bf820417c 2023-05-15T15:08:19+02:00 Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals Nathalia Sernizon Guimarães Milena Maria Moreira Guimarães Adriana Maria Kakehasi Mariana Guimarães Penido de Paula Júlia Fonseca de Morais Caporali Érica Leandro Marciano Vieira Pedro Rezende Tanajura Unaí Tupinambás https://doi.org/10.1590/0037-8682-0475-2017 https://doaj.org/article/f62916e58b31488faad39a4bf820417c EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000500596&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0475-2017 https://doaj.org/article/f62916e58b31488faad39a4bf820417c Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 5, Pp 596-602 Bone mass Vitamin D HIV People living with HIV Biomarker Arctic medicine. Tropical medicine RC955-962 article ftdoajarticles https://doi.org/10.1590/0037-8682-0475-2017 2022-12-30T21:49:51Z Abstract INTRODUCTION: The prevalence of low bone mass is 3 times higher in people living with human immunodeficiency virus (PLWH) and using antiretrovirals than in the HIV-unaffected population. Changes in vitamin D levels is one of the factors associated with decreased bone mass. The objective of this study is to evaluate the low bone mass and altered vitamin D levels in PLWH who have not been exposed to antiretrovirals. METHODS: A cross-sectional study was carried out with HIV-infected individuals between the ages of 18 and 55 years immediately prior to the start of antiretroviral therapy in a specialized reference center focusing on infectious and parasitic diseases. Results of clinical examination (patient’s weight, height, blood pressure, and clinical history), laboratory tests, and X-ray absorptiometry, were collected. RESULTS: Sixty patients were included, with a mean age of 34 years. Nine (16.7%) patients presented with low bone mass and 4 (7.1%) patients showed low total femur BMD. Analysis revealed that 23.3% and 36.7% of the patients had deficient and insufficient levels of 25-hydroxyvitamin D3, respectively. CONCLUSIONS: Our study population presented with compromised bone health and with low bone mineral density and 25-(OH)-vitamin D levels. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 51 5 596 602 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Bone mass Vitamin D HIV People living with HIV Biomarker Arctic medicine. Tropical medicine RC955-962 |
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Bone mass Vitamin D HIV People living with HIV Biomarker Arctic medicine. Tropical medicine RC955-962 Nathalia Sernizon Guimarães Milena Maria Moreira Guimarães Adriana Maria Kakehasi Mariana Guimarães Penido de Paula Júlia Fonseca de Morais Caporali Érica Leandro Marciano Vieira Pedro Rezende Tanajura Unaí Tupinambás Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
topic_facet |
Bone mass Vitamin D HIV People living with HIV Biomarker Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: The prevalence of low bone mass is 3 times higher in people living with human immunodeficiency virus (PLWH) and using antiretrovirals than in the HIV-unaffected population. Changes in vitamin D levels is one of the factors associated with decreased bone mass. The objective of this study is to evaluate the low bone mass and altered vitamin D levels in PLWH who have not been exposed to antiretrovirals. METHODS: A cross-sectional study was carried out with HIV-infected individuals between the ages of 18 and 55 years immediately prior to the start of antiretroviral therapy in a specialized reference center focusing on infectious and parasitic diseases. Results of clinical examination (patient’s weight, height, blood pressure, and clinical history), laboratory tests, and X-ray absorptiometry, were collected. RESULTS: Sixty patients were included, with a mean age of 34 years. Nine (16.7%) patients presented with low bone mass and 4 (7.1%) patients showed low total femur BMD. Analysis revealed that 23.3% and 36.7% of the patients had deficient and insufficient levels of 25-hydroxyvitamin D3, respectively. CONCLUSIONS: Our study population presented with compromised bone health and with low bone mineral density and 25-(OH)-vitamin D levels. |
format |
Article in Journal/Newspaper |
author |
Nathalia Sernizon Guimarães Milena Maria Moreira Guimarães Adriana Maria Kakehasi Mariana Guimarães Penido de Paula Júlia Fonseca de Morais Caporali Érica Leandro Marciano Vieira Pedro Rezende Tanajura Unaí Tupinambás |
author_facet |
Nathalia Sernizon Guimarães Milena Maria Moreira Guimarães Adriana Maria Kakehasi Mariana Guimarães Penido de Paula Júlia Fonseca de Morais Caporali Érica Leandro Marciano Vieira Pedro Rezende Tanajura Unaí Tupinambás |
author_sort |
Nathalia Sernizon Guimarães |
title |
Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
title_short |
Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
title_full |
Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
title_fullStr |
Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
title_full_unstemmed |
Prevalence of low bone mass and changes in vitamin D levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
title_sort |
prevalence of low bone mass and changes in vitamin d levels in human immunodeficiency virus-infected adults unexposed to antiretrovirals |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
url |
https://doi.org/10.1590/0037-8682-0475-2017 https://doaj.org/article/f62916e58b31488faad39a4bf820417c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 5, Pp 596-602 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000500596&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0475-2017 https://doaj.org/article/f62916e58b31488faad39a4bf820417c |
op_doi |
https://doi.org/10.1590/0037-8682-0475-2017 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
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51 |
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5 |
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596 |
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