Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy.
Background Emerging arboviral diseases in Europe pose a challenge due to difficulties in detecting and diagnosing cases during the initial circulation of the pathogen. Early outbreak detection enables public health authorities to take effective actions to reduce disease transmission. Quantification...
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ftdoajarticles:oai:doaj.org/article:f54837b0812942829abe7e113c889d4a 2023-10-09T21:49:13+02:00 Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. Mattia Manica Giovanni Marini Angelo Solimini Giorgio Guzzetta Piero Poletti Paola Scognamiglio Chiara Virgillito Alessandra Della Torre Stefano Merler Roberto Rosà Francesco Vairo Beniamino Caputo 2023-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0011610 https://doaj.org/article/f54837b0812942829abe7e113c889d4a EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0011610 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0011610 https://doaj.org/article/f54837b0812942829abe7e113c889d4a PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011610 (2023) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.1371/journal.pntd.0011610 2023-09-24T00:38:30Z Background Emerging arboviral diseases in Europe pose a challenge due to difficulties in detecting and diagnosing cases during the initial circulation of the pathogen. Early outbreak detection enables public health authorities to take effective actions to reduce disease transmission. Quantification of the reporting delays of cases is vital to plan and assess surveillance and control strategies. Here, we provide estimates of reporting delays during an emerging arboviral outbreak and indications on how delays may have impacted onward transmission. Methodology/principal findings Using descriptive statistics and Kaplan-Meyer curves we analyzed case reporting delays (the period between the date of symptom onset and the date of notification to the public health authorities) during the 2017 Italian chikungunya outbreak. We further investigated the effect of outbreak detection on reporting delays by means of a Cox proportional hazard model. We estimated that the overall median reporting delay was 15.5 days, but this was reduced to 8 days after the notification of the first case. Cases with symptom onset after outbreak detection had about a 3.5 times higher reporting rate, however only 3.6% were notified within 24h from symptom onset. Remarkably, we found that 45.9% of identified cases developed symptoms before the detection of the outbreak. Conclusions/significance These results suggest that efforts should be undertaken to improve the early detection and identification of arboviral cases, as well as the management of vector species to mitigate the impact of long reporting delays. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 17 9 e0011610 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Mattia Manica Giovanni Marini Angelo Solimini Giorgio Guzzetta Piero Poletti Paola Scognamiglio Chiara Virgillito Alessandra Della Torre Stefano Merler Roberto Rosà Francesco Vairo Beniamino Caputo Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Emerging arboviral diseases in Europe pose a challenge due to difficulties in detecting and diagnosing cases during the initial circulation of the pathogen. Early outbreak detection enables public health authorities to take effective actions to reduce disease transmission. Quantification of the reporting delays of cases is vital to plan and assess surveillance and control strategies. Here, we provide estimates of reporting delays during an emerging arboviral outbreak and indications on how delays may have impacted onward transmission. Methodology/principal findings Using descriptive statistics and Kaplan-Meyer curves we analyzed case reporting delays (the period between the date of symptom onset and the date of notification to the public health authorities) during the 2017 Italian chikungunya outbreak. We further investigated the effect of outbreak detection on reporting delays by means of a Cox proportional hazard model. We estimated that the overall median reporting delay was 15.5 days, but this was reduced to 8 days after the notification of the first case. Cases with symptom onset after outbreak detection had about a 3.5 times higher reporting rate, however only 3.6% were notified within 24h from symptom onset. Remarkably, we found that 45.9% of identified cases developed symptoms before the detection of the outbreak. Conclusions/significance These results suggest that efforts should be undertaken to improve the early detection and identification of arboviral cases, as well as the management of vector species to mitigate the impact of long reporting delays. |
format |
Article in Journal/Newspaper |
author |
Mattia Manica Giovanni Marini Angelo Solimini Giorgio Guzzetta Piero Poletti Paola Scognamiglio Chiara Virgillito Alessandra Della Torre Stefano Merler Roberto Rosà Francesco Vairo Beniamino Caputo |
author_facet |
Mattia Manica Giovanni Marini Angelo Solimini Giorgio Guzzetta Piero Poletti Paola Scognamiglio Chiara Virgillito Alessandra Della Torre Stefano Merler Roberto Rosà Francesco Vairo Beniamino Caputo |
author_sort |
Mattia Manica |
title |
Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. |
title_short |
Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. |
title_full |
Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. |
title_fullStr |
Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. |
title_full_unstemmed |
Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy. |
title_sort |
reporting delays of chikungunya cases during the 2017 outbreak in lazio region, italy. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2023 |
url |
https://doi.org/10.1371/journal.pntd.0011610 https://doaj.org/article/f54837b0812942829abe7e113c889d4a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011610 (2023) |
op_relation |
https://doi.org/10.1371/journal.pntd.0011610 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0011610 https://doaj.org/article/f54837b0812942829abe7e113c889d4a |
op_doi |
https://doi.org/10.1371/journal.pntd.0011610 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
17 |
container_issue |
9 |
container_start_page |
e0011610 |
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1779312226164801536 |