THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS
The optimization of enzymatic synthesis for lauroyl-N-methyl glucamide surfactants is studied. The fraction of palm kernel oil namely lauric acid (AL) was amidificationed with N-methyl glucamine (MGL) to produce lauroyl-N-methyl glucamide. Study was carried out by using immobilized lipase from Candi...
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Department of Chemistry, Universitas Gadjah Mada
2011
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ftdoajarticles:oai:doaj.org/article:f496ca8ad08441888c78365073109865 2023-05-15T13:59:22+02:00 THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS Zuhrina Masyithah Seri Bima Sembiring Zul Alfian Tjahjono Herawan 2011-12-01T00:00:00Z https://doi.org/10.22146/ijc.21384 https://doaj.org/article/f496ca8ad08441888c78365073109865 EN eng Department of Chemistry, Universitas Gadjah Mada https://jurnal.ugm.ac.id/ijc/article/view/21384 https://doaj.org/toc/1411-9420 https://doaj.org/toc/2460-1578 1411-9420 2460-1578 doi:10.22146/ijc.21384 https://doaj.org/article/f496ca8ad08441888c78365073109865 Indonesian Journal of Chemistry, Vol 11, Iss 3, Pp 223-228 (2011) amidification lauric acid N-methyl glucamine Response Surface Methodology Chemistry QD1-999 article 2011 ftdoajarticles https://doi.org/10.22146/ijc.21384 2022-12-31T10:28:13Z The optimization of enzymatic synthesis for lauroyl-N-methyl glucamide surfactants is studied. The fraction of palm kernel oil namely lauric acid (AL) was amidificationed with N-methyl glucamine (MGL) to produce lauroyl-N-methyl glucamide. Study was carried out by using immobilized lipase from Candida antarctica (Novozyme 435®), and tert-amylalcohol as a solvent. Response Surface Methodology (RSM) based on a five level, three variable design was employed, firstly, for studying the interactive effect of various parameters on the reaction, and secondly, for the optimization. The reaction parameters observed were Novozyme concentration, substrate molar ratio, and temperature. Simultaneously increasing Novozyme concentration, substrate molar ratio, and temperature improves the reaction yield and the effect of temperature is noted more significant. The expected optimum condition was at molar ratio MGL:AL 1:1, the Novozyme concentration of 8% and the reaction temperature of 50-55 °C. The reactions at the optimum condition produce the convertion of lauric acid of 64.5% and yield of 96.5%. With the optimization procedure the higher alkyl glucamide yield was achieved. Article in Journal/Newspaper Antarc* Antarctica Directory of Open Access Journals: DOAJ Articles Indonesian Journal of Chemistry 11 3 223 228 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
amidification lauric acid N-methyl glucamine Response Surface Methodology Chemistry QD1-999 |
spellingShingle |
amidification lauric acid N-methyl glucamine Response Surface Methodology Chemistry QD1-999 Zuhrina Masyithah Seri Bima Sembiring Zul Alfian Tjahjono Herawan THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
topic_facet |
amidification lauric acid N-methyl glucamine Response Surface Methodology Chemistry QD1-999 |
description |
The optimization of enzymatic synthesis for lauroyl-N-methyl glucamide surfactants is studied. The fraction of palm kernel oil namely lauric acid (AL) was amidificationed with N-methyl glucamine (MGL) to produce lauroyl-N-methyl glucamide. Study was carried out by using immobilized lipase from Candida antarctica (Novozyme 435®), and tert-amylalcohol as a solvent. Response Surface Methodology (RSM) based on a five level, three variable design was employed, firstly, for studying the interactive effect of various parameters on the reaction, and secondly, for the optimization. The reaction parameters observed were Novozyme concentration, substrate molar ratio, and temperature. Simultaneously increasing Novozyme concentration, substrate molar ratio, and temperature improves the reaction yield and the effect of temperature is noted more significant. The expected optimum condition was at molar ratio MGL:AL 1:1, the Novozyme concentration of 8% and the reaction temperature of 50-55 °C. The reactions at the optimum condition produce the convertion of lauric acid of 64.5% and yield of 96.5%. With the optimization procedure the higher alkyl glucamide yield was achieved. |
format |
Article in Journal/Newspaper |
author |
Zuhrina Masyithah Seri Bima Sembiring Zul Alfian Tjahjono Herawan |
author_facet |
Zuhrina Masyithah Seri Bima Sembiring Zul Alfian Tjahjono Herawan |
author_sort |
Zuhrina Masyithah |
title |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_short |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_full |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_fullStr |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_full_unstemmed |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_sort |
optimization of enzymatic synthesis for lauroyl-n-methyl glucamide surfactants |
publisher |
Department of Chemistry, Universitas Gadjah Mada |
publishDate |
2011 |
url |
https://doi.org/10.22146/ijc.21384 https://doaj.org/article/f496ca8ad08441888c78365073109865 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Indonesian Journal of Chemistry, Vol 11, Iss 3, Pp 223-228 (2011) |
op_relation |
https://jurnal.ugm.ac.id/ijc/article/view/21384 https://doaj.org/toc/1411-9420 https://doaj.org/toc/2460-1578 1411-9420 2460-1578 doi:10.22146/ijc.21384 https://doaj.org/article/f496ca8ad08441888c78365073109865 |
op_doi |
https://doi.org/10.22146/ijc.21384 |
container_title |
Indonesian Journal of Chemistry |
container_volume |
11 |
container_issue |
3 |
container_start_page |
223 |
op_container_end_page |
228 |
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1766267910225920000 |