Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo.
Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationall...
Published in: | PLoS Neglected Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:f44a64ce085447469a4bc2be0f8c565d 2023-05-15T15:01:05+02:00 Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. Dieudonne Mumba Elaine Bohorquez Jane Messina Victor Kande Steven M Taylor Antoinette K Tshefu Jeremie Muwonga Melchior M Kashamuka Michael Emch Richard Tidwell Philippe Büscher Steven R Meshnick 2011-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001246 https://doaj.org/article/f44a64ce085447469a4bc2be0f8c565d EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3149009?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001246 https://doaj.org/article/f44a64ce085447469a4bc2be0f8c565d PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1246 (2011) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2011 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001246 2022-12-31T03:54:41Z Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were positive by ELISA. Three of these were also positive by trypanolysis and/or PCR. From these data, we estimate that there were 18,592 people with HAT (95% confidence interval, 4,883-32,302) in the DRC in 2007, slightly more than twice as many as were reported. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 5 8 e1246 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Dieudonne Mumba Elaine Bohorquez Jane Messina Victor Kande Steven M Taylor Antoinette K Tshefu Jeremie Muwonga Melchior M Kashamuka Michael Emch Richard Tidwell Philippe Büscher Steven R Meshnick Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were positive by ELISA. Three of these were also positive by trypanolysis and/or PCR. From these data, we estimate that there were 18,592 people with HAT (95% confidence interval, 4,883-32,302) in the DRC in 2007, slightly more than twice as many as were reported. |
format |
Article in Journal/Newspaper |
author |
Dieudonne Mumba Elaine Bohorquez Jane Messina Victor Kande Steven M Taylor Antoinette K Tshefu Jeremie Muwonga Melchior M Kashamuka Michael Emch Richard Tidwell Philippe Büscher Steven R Meshnick |
author_facet |
Dieudonne Mumba Elaine Bohorquez Jane Messina Victor Kande Steven M Taylor Antoinette K Tshefu Jeremie Muwonga Melchior M Kashamuka Michael Emch Richard Tidwell Philippe Büscher Steven R Meshnick |
author_sort |
Dieudonne Mumba |
title |
Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. |
title_short |
Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. |
title_full |
Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. |
title_fullStr |
Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. |
title_full_unstemmed |
Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. |
title_sort |
prevalence of human african trypanosomiasis in the democratic republic of the congo. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2011 |
url |
https://doi.org/10.1371/journal.pntd.0001246 https://doaj.org/article/f44a64ce085447469a4bc2be0f8c565d |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1246 (2011) |
op_relation |
http://europepmc.org/articles/PMC3149009?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001246 https://doaj.org/article/f44a64ce085447469a4bc2be0f8c565d |
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https://doi.org/10.1371/journal.pntd.0001246 |
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PLoS Neglected Tropical Diseases |
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5 |
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8 |
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e1246 |
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