Determination of HIV Tropism in Patients with Antiretroviral Therapy Failure in Arkhangelsk Region

• Published in: Problems of Particularly Dangerous Infections
• Main Authors: Yu. V. Ostankova, V. S. Davydenko, A. N. Shchemelev, E. B. Zueva, P. A. Virolainen, Areg A. Totolyan
• Format: Article in Journal/Newspaper
• Language: Russian
• Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2022
• Subjects: human immunodeficiency virus (hiv); hiv co-receptor tropism; ccr5; cxcr4; ccr5 receptor antagonists; env gene; genotypic diagnostics; Infectious and parasitic diseases; RC109-216; Garrido; Arkhangelsk
• Online Access: https://doi.org/10.21055/0370-1069-2022-3-120-128; https://doaj.org/article/f3daa5b0ad9c444c8ba9fba0dfb0d922

The aim of the study was to determine the tropism of the human immunodeficiency virus in patients with virological failure of antiretroviral therapy (ART) from the Arkhangelsk Region based on the analysis of the env gene V3 loop nucleotide sequence.Materials and methods. We used blood plasma samples...