Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France.
Cryptosporidium spp. infections are the most frequent parasitic cause of diarrhea in humans and cattle. However, asymptomatic cases are less often documented than symptomatic cases or cases with experimentally infected animals. Cryptosporidium (C.) hominis infection accounts for the majority of pedi...
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ftdoajarticles:oai:doaj.org/article:f3c487df39f54c808d5d6a2769cfcc09 2023-05-15T15:16:33+02:00 Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. Romy Razakandrainibe El Hadji Ibrahima Diawara Damien Costa Laetitia Le Goff Denis Lemeteil Jean Jacques Ballet Gilles Gargala Loïc Favennec 2018-03-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006355 https://doaj.org/article/f3c487df39f54c808d5d6a2769cfcc09 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5892941?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006355 https://doaj.org/article/f3c487df39f54c808d5d6a2769cfcc09 PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006355 (2018) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006355 2022-12-31T10:52:54Z Cryptosporidium spp. infections are the most frequent parasitic cause of diarrhea in humans and cattle. However, asymptomatic cases are less often documented than symptomatic cases or cases with experimentally infected animals. Cryptosporidium (C.) hominis infection accounts for the majority of pediatric cases in several countries, while C. parvum is a major cause of diarrhea in neonatal calves. In cattle Cryptosporidium spp. infection can be caused by C. parvum, C. bovis, C.andersoni and C. ryanae, and recently, reports of cattle cases of C. hominis cryptosporidiosis cases suggest that the presence of C. hominis in calves was previously underestimated.From February to November 2015, Cryptosporidium spp. infected calves were detected in 29/44 randomly included farms from 5 geographic regions of France. C. hominis and C. parvum were found in 12/44 and 26/44 farms, respectively with higher C. hominis prevalence in the western region. In 9 farms, both C. parvum and C. hominis were detected. Eighty-six of 412 (73/342 asymptomatic and 13/70 symptomatic) one to nine-week-old calves shed C. hominis or C. parvum oocysts (15 and 71 calves, respectively), with no mixed infection detected. The predominant C. hominis IbA9G3 genotype was present in all regions, and more frequent in the western region. An incompletely characterized Ib, and the IbA13G3, IbA9G2 and IbA14G2 genotypes were present only in the western region. For C. parvum, the most frequent genotype was IIaA16G3R1 with no geographic clustering. Most C. hominis infected calves were asymptomatic, with some exceptions of IbA9G2 and IbA9G3 isolates, while C. parvum IIaA16G3R1 was associated with symptoms.Present results indicate for the first time that in several geographic regions of France, C. hominis was present in about one fifth of both asymptomatic and symptomatic infected calves, with isolated genotypes likely associated with human infection. Further investigations are aimed at documenting direct or indirect transmissions between livestock and humans. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 12 3 e0006355 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Romy Razakandrainibe El Hadji Ibrahima Diawara Damien Costa Laetitia Le Goff Denis Lemeteil Jean Jacques Ballet Gilles Gargala Loïc Favennec Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Cryptosporidium spp. infections are the most frequent parasitic cause of diarrhea in humans and cattle. However, asymptomatic cases are less often documented than symptomatic cases or cases with experimentally infected animals. Cryptosporidium (C.) hominis infection accounts for the majority of pediatric cases in several countries, while C. parvum is a major cause of diarrhea in neonatal calves. In cattle Cryptosporidium spp. infection can be caused by C. parvum, C. bovis, C.andersoni and C. ryanae, and recently, reports of cattle cases of C. hominis cryptosporidiosis cases suggest that the presence of C. hominis in calves was previously underestimated.From February to November 2015, Cryptosporidium spp. infected calves were detected in 29/44 randomly included farms from 5 geographic regions of France. C. hominis and C. parvum were found in 12/44 and 26/44 farms, respectively with higher C. hominis prevalence in the western region. In 9 farms, both C. parvum and C. hominis were detected. Eighty-six of 412 (73/342 asymptomatic and 13/70 symptomatic) one to nine-week-old calves shed C. hominis or C. parvum oocysts (15 and 71 calves, respectively), with no mixed infection detected. The predominant C. hominis IbA9G3 genotype was present in all regions, and more frequent in the western region. An incompletely characterized Ib, and the IbA13G3, IbA9G2 and IbA14G2 genotypes were present only in the western region. For C. parvum, the most frequent genotype was IIaA16G3R1 with no geographic clustering. Most C. hominis infected calves were asymptomatic, with some exceptions of IbA9G2 and IbA9G3 isolates, while C. parvum IIaA16G3R1 was associated with symptoms.Present results indicate for the first time that in several geographic regions of France, C. hominis was present in about one fifth of both asymptomatic and symptomatic infected calves, with isolated genotypes likely associated with human infection. Further investigations are aimed at documenting direct or indirect transmissions between livestock and humans. |
format |
Article in Journal/Newspaper |
author |
Romy Razakandrainibe El Hadji Ibrahima Diawara Damien Costa Laetitia Le Goff Denis Lemeteil Jean Jacques Ballet Gilles Gargala Loïc Favennec |
author_facet |
Romy Razakandrainibe El Hadji Ibrahima Diawara Damien Costa Laetitia Le Goff Denis Lemeteil Jean Jacques Ballet Gilles Gargala Loïc Favennec |
author_sort |
Romy Razakandrainibe |
title |
Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. |
title_short |
Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. |
title_full |
Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. |
title_fullStr |
Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. |
title_full_unstemmed |
Common occurrence of Cryptosporidium hominis in asymptomatic and symptomatic calves in France. |
title_sort |
common occurrence of cryptosporidium hominis in asymptomatic and symptomatic calves in france. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2018 |
url |
https://doi.org/10.1371/journal.pntd.0006355 https://doaj.org/article/f3c487df39f54c808d5d6a2769cfcc09 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006355 (2018) |
op_relation |
http://europepmc.org/articles/PMC5892941?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006355 https://doaj.org/article/f3c487df39f54c808d5d6a2769cfcc09 |
op_doi |
https://doi.org/10.1371/journal.pntd.0006355 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
12 |
container_issue |
3 |
container_start_page |
e0006355 |
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1766346845595893760 |