Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats
Objective: To evaluate the potential of both jamun (Syzygium cumini) seed and fruit extracts against hyperglycemia. Methods: Male Sprague Dawley rats were used to evaluate hypoglycemic potential of jamun extracts. Purposely, jamun fruit and seed's ethanolic extracts based diets were provided to...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2017
|
Subjects: | |
Online Access: | https://doi.org/10.1016/j.apjtb.2017.07.006 https://doaj.org/article/f2a178decf5d4e55a5e6eeef7bf861fe |
id |
ftdoajarticles:oai:doaj.org/article:f2a178decf5d4e55a5e6eeef7bf861fe |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:f2a178decf5d4e55a5e6eeef7bf861fe 2023-05-15T15:07:19+02:00 Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats Ahmad Raza Masood Sadiq Butt Iahtisham-Ul-Haq Hafiz Ansar Rasul Suleria 2017-08-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.07.006 https://doaj.org/article/f2a178decf5d4e55a5e6eeef7bf861fe EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117307608 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.07.006 https://doaj.org/article/f2a178decf5d4e55a5e6eeef7bf861fe Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 8, Pp 750-754 (2017) Hyperglycemia Jamun seed and fruit extract Glucose Insulin Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.07.006 2022-12-31T03:09:09Z Objective: To evaluate the potential of both jamun (Syzygium cumini) seed and fruit extracts against hyperglycemia. Methods: Male Sprague Dawley rats were used to evaluate hypoglycemic potential of jamun extracts. Purposely, jamun fruit and seed's ethanolic extracts based diets were provided to normal and high sucrose diet induced hyperglycemic/diabetic rats for sixty days. The serum glucose and insulin levels were monitored at monthly intervals to evaluate hypoglycemic effect of jamun extracts. Results: The results of instant research depicted that both seed and fruit extracts reduce the blood glucose level significantly and also regulate the insulin levels in hyperglycemic rats. It was noted that jamun fruit extract attenuated serum glucose levels to 5.35% and 12.29% in normal and hyperglycemic rats, respectively; while insulin levels were improved by 2.82% and 6.19%, correspondingly. Whereas, jamun seed extract reduced glucose to 7.04% & 14.36% and showed 3.56% & 7.24% higher insulin levels in normal & hyperglycemic rats, respectively. Conclusions: The present research revealed that both jamun fruit and seeds have potent prophylactic role against hyperglycemia. In this respect, diet based regimen may be tailored using jamun fruit/seed and their extracts to alleviate hyperglycemia. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 8 750 754 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Hyperglycemia Jamun seed and fruit extract Glucose Insulin Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Hyperglycemia Jamun seed and fruit extract Glucose Insulin Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Ahmad Raza Masood Sadiq Butt Iahtisham-Ul-Haq Hafiz Ansar Rasul Suleria Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
topic_facet |
Hyperglycemia Jamun seed and fruit extract Glucose Insulin Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the potential of both jamun (Syzygium cumini) seed and fruit extracts against hyperglycemia. Methods: Male Sprague Dawley rats were used to evaluate hypoglycemic potential of jamun extracts. Purposely, jamun fruit and seed's ethanolic extracts based diets were provided to normal and high sucrose diet induced hyperglycemic/diabetic rats for sixty days. The serum glucose and insulin levels were monitored at monthly intervals to evaluate hypoglycemic effect of jamun extracts. Results: The results of instant research depicted that both seed and fruit extracts reduce the blood glucose level significantly and also regulate the insulin levels in hyperglycemic rats. It was noted that jamun fruit extract attenuated serum glucose levels to 5.35% and 12.29% in normal and hyperglycemic rats, respectively; while insulin levels were improved by 2.82% and 6.19%, correspondingly. Whereas, jamun seed extract reduced glucose to 7.04% & 14.36% and showed 3.56% & 7.24% higher insulin levels in normal & hyperglycemic rats, respectively. Conclusions: The present research revealed that both jamun fruit and seeds have potent prophylactic role against hyperglycemia. In this respect, diet based regimen may be tailored using jamun fruit/seed and their extracts to alleviate hyperglycemia. |
format |
Article in Journal/Newspaper |
author |
Ahmad Raza Masood Sadiq Butt Iahtisham-Ul-Haq Hafiz Ansar Rasul Suleria |
author_facet |
Ahmad Raza Masood Sadiq Butt Iahtisham-Ul-Haq Hafiz Ansar Rasul Suleria |
author_sort |
Ahmad Raza |
title |
Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
title_short |
Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
title_full |
Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
title_fullStr |
Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
title_full_unstemmed |
Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
title_sort |
jamun (syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.07.006 https://doaj.org/article/f2a178decf5d4e55a5e6eeef7bf861fe |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 8, Pp 750-754 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117307608 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.07.006 https://doaj.org/article/f2a178decf5d4e55a5e6eeef7bf861fe |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.07.006 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
8 |
container_start_page |
750 |
op_container_end_page |
754 |
_version_ |
1766338855489765376 |