Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae
Objective: To evaluate the larvicidal efficacy of eight volatile components of essential oils against 3rd instar larvae of Anopheles gambiae s.s. Methods: Larvicidal effects of each compound were evaluated in both laboratory and semi-field trials. Stock solution was prepared and serial dilutions wer...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2016
|
Subjects: | |
Online Access: | https://doi.org/10.1016/j.apjtb.2016.03.001 https://doaj.org/article/f2618cfde8564c7792e3c73c0b87d3e7 |
id |
ftdoajarticles:oai:doaj.org/article:f2618cfde8564c7792e3c73c0b87d3e7 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:f2618cfde8564c7792e3c73c0b87d3e7 2023-05-15T15:12:54+02:00 Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae Eliningaya J. Kweka Tamires Cardoso Lima Chrian M. Marciale Damião Pergentino de Sousa 2016-04-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.03.001 https://doaj.org/article/f2618cfde8564c7792e3c73c0b87d3e7 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115308455 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.03.001 https://doaj.org/article/f2618cfde8564c7792e3c73c0b87d3e7 Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 4, Pp 290-294 (2016) Larvicidal activity Malaria Anopheles gambiae s.s Essential oils Monoterpenes Natural products Mosquito Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2016 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.03.001 2022-12-31T10:13:16Z Objective: To evaluate the larvicidal efficacy of eight volatile components of essential oils against 3rd instar larvae of Anopheles gambiae s.s. Methods: Larvicidal effects of each compound were evaluated in both laboratory and semi-field trials. Stock solution was prepared and serial dilutions were made in six concentrations for each compound. A total of 20 larvae were exposed to larvicides for each replicate and monitored at intervals of 12, 24, 48 and 72 h. Larvae monitoring was done on basis of dead and live larvae in all intervals. Results: All assayed compounds were larvicides and presented varying degrees of larval toxicity, with LC50 values ranging from 1.28 to 1938.92 mg/L depending on the treatment time (12, 24, 48 or 72 h). (−)-Perillyl alcohol presented the strongest larvicidal activity towards Anopheles gambiae larvae, with LC50 values of 73.60, 18.36, 1.72 and 1.28 mg/L after 12, 24, 48 and 72 h of exposure, respectively. The next strongest were (−)-isopulegol (LC50 = 135.10, 49.39, 34.39 and 20.22 mg/L) and (−)-carvone epoxide (LC50 = 168.86, 124.74, 80.84 and 23.46 mg/L). After 12, 24 and 48 h of treatment, hydroxydihydrocarvone was the least toxic compound, with LC50 values of 1938.92, 1172.18 and 401.03 mg/L, respectively. Conclusions: The data obtained in this study suggest that all evaluated monoterpenes, especially (−)-perillyl alcohol, have remarkable larvicidal effects and may be considered as potential sources for the development of suitable natural larvicides for mosquito management programs. Further small-scale field trials should be conducted. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 6 4 290 294 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Larvicidal activity Malaria Anopheles gambiae s.s Essential oils Monoterpenes Natural products Mosquito Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Larvicidal activity Malaria Anopheles gambiae s.s Essential oils Monoterpenes Natural products Mosquito Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Eliningaya J. Kweka Tamires Cardoso Lima Chrian M. Marciale Damião Pergentino de Sousa Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae |
topic_facet |
Larvicidal activity Malaria Anopheles gambiae s.s Essential oils Monoterpenes Natural products Mosquito Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the larvicidal efficacy of eight volatile components of essential oils against 3rd instar larvae of Anopheles gambiae s.s. Methods: Larvicidal effects of each compound were evaluated in both laboratory and semi-field trials. Stock solution was prepared and serial dilutions were made in six concentrations for each compound. A total of 20 larvae were exposed to larvicides for each replicate and monitored at intervals of 12, 24, 48 and 72 h. Larvae monitoring was done on basis of dead and live larvae in all intervals. Results: All assayed compounds were larvicides and presented varying degrees of larval toxicity, with LC50 values ranging from 1.28 to 1938.92 mg/L depending on the treatment time (12, 24, 48 or 72 h). (−)-Perillyl alcohol presented the strongest larvicidal activity towards Anopheles gambiae larvae, with LC50 values of 73.60, 18.36, 1.72 and 1.28 mg/L after 12, 24, 48 and 72 h of exposure, respectively. The next strongest were (−)-isopulegol (LC50 = 135.10, 49.39, 34.39 and 20.22 mg/L) and (−)-carvone epoxide (LC50 = 168.86, 124.74, 80.84 and 23.46 mg/L). After 12, 24 and 48 h of treatment, hydroxydihydrocarvone was the least toxic compound, with LC50 values of 1938.92, 1172.18 and 401.03 mg/L, respectively. Conclusions: The data obtained in this study suggest that all evaluated monoterpenes, especially (−)-perillyl alcohol, have remarkable larvicidal effects and may be considered as potential sources for the development of suitable natural larvicides for mosquito management programs. Further small-scale field trials should be conducted. |
format |
Article in Journal/Newspaper |
author |
Eliningaya J. Kweka Tamires Cardoso Lima Chrian M. Marciale Damião Pergentino de Sousa |
author_facet |
Eliningaya J. Kweka Tamires Cardoso Lima Chrian M. Marciale Damião Pergentino de Sousa |
author_sort |
Eliningaya J. Kweka |
title |
Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae |
title_short |
Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae |
title_full |
Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae |
title_fullStr |
Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae |
title_full_unstemmed |
Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae |
title_sort |
larvicidal efficacy of monoterpenes against the larvae of anopheles gambiae |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2016 |
url |
https://doi.org/10.1016/j.apjtb.2016.03.001 https://doaj.org/article/f2618cfde8564c7792e3c73c0b87d3e7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 4, Pp 290-294 (2016) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115308455 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.03.001 https://doaj.org/article/f2618cfde8564c7792e3c73c0b87d3e7 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.03.001 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
6 |
container_issue |
4 |
container_start_page |
290 |
op_container_end_page |
294 |
_version_ |
1766343534407843840 |