Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy
Abstract Background The rate of admissions to hospital with bronchiolitis has increased over the past years. The reasons for this are likely to be multifactorial including improved survival of preterm infants. Aim To assess the severity of viral bronchiolitis in preterm compared to term infants admi...
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ftdoajarticles:oai:doaj.org/article:f234b544e72248c58c4157b22d81c8bd 2023-05-15T15:12:22+02:00 Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy Noussa R. El Basha Huda Marzouk May M. Sherif Amani A. El Kholy 2019-03-01T00:00:00Z https://doi.org/10.1186/s42506-019-0015-8 https://doaj.org/article/f234b544e72248c58c4157b22d81c8bd EN eng SpringerOpen http://link.springer.com/article/10.1186/s42506-019-0015-8 https://doaj.org/toc/2090-262X doi:10.1186/s42506-019-0015-8 2090-262X https://doaj.org/article/f234b544e72248c58c4157b22d81c8bd Journal of the Egyptian Public Health Association, Vol 94, Iss 1, Pp 1-6 (2019) Bronchiolitis Viruses Preterm Severity Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1186/s42506-019-0015-8 2022-12-31T14:47:02Z Abstract Background The rate of admissions to hospital with bronchiolitis has increased over the past years. The reasons for this are likely to be multifactorial including improved survival of preterm infants. Aim To assess the severity of viral bronchiolitis in preterm compared to term infants admitted at a tertiary hospital in Cairo, Egypt, based on the outcome. Patients and methods This prospective study was conducted throughout a 3-year period from September 2011 to October 2014. It included 153 infants, 74 healthy preterm, and 79 healthy term infants admitted with clinical diagnosis of bronchiolitis at a tertiary hospital in Cairo, Egypt. Bronchiolitis severity score (BSS) was recorded, and nasopharyngeal swabs were obtained from each patient at the time of presentation. Viruses were identified using reverse transcription polymerase chain reaction (RT-PCR). The clinical course and patient’s outcome were recorded. Results This study recorded a significantly more severe BSS for preterm compared to term infants. The preterm group had an increased mean length of hospital stay and oxygen therapy and was more likely to need intensive care unit admission and mechanical ventilation (MV) compared to the term group. The mean (± SD) BSS for infections with h-MPV, RSV, and para-influenza 3 was more significantly severe in preterm compared to term infants. Bacterial co-infection was significantly correlated with severity scoring in both groups. Conclusion Prematurity significantly affects the severity of bronchiolitis, and this underscores the importance of early categorization as a high-risk group on their first visit. The physician should be aware that their illness runs a more severe course, even if they have no underlying disorders. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of the Egyptian Public Health Association 94 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Bronchiolitis Viruses Preterm Severity Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Bronchiolitis Viruses Preterm Severity Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Noussa R. El Basha Huda Marzouk May M. Sherif Amani A. El Kholy Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
topic_facet |
Bronchiolitis Viruses Preterm Severity Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Abstract Background The rate of admissions to hospital with bronchiolitis has increased over the past years. The reasons for this are likely to be multifactorial including improved survival of preterm infants. Aim To assess the severity of viral bronchiolitis in preterm compared to term infants admitted at a tertiary hospital in Cairo, Egypt, based on the outcome. Patients and methods This prospective study was conducted throughout a 3-year period from September 2011 to October 2014. It included 153 infants, 74 healthy preterm, and 79 healthy term infants admitted with clinical diagnosis of bronchiolitis at a tertiary hospital in Cairo, Egypt. Bronchiolitis severity score (BSS) was recorded, and nasopharyngeal swabs were obtained from each patient at the time of presentation. Viruses were identified using reverse transcription polymerase chain reaction (RT-PCR). The clinical course and patient’s outcome were recorded. Results This study recorded a significantly more severe BSS for preterm compared to term infants. The preterm group had an increased mean length of hospital stay and oxygen therapy and was more likely to need intensive care unit admission and mechanical ventilation (MV) compared to the term group. The mean (± SD) BSS for infections with h-MPV, RSV, and para-influenza 3 was more significantly severe in preterm compared to term infants. Bacterial co-infection was significantly correlated with severity scoring in both groups. Conclusion Prematurity significantly affects the severity of bronchiolitis, and this underscores the importance of early categorization as a high-risk group on their first visit. The physician should be aware that their illness runs a more severe course, even if they have no underlying disorders. |
format |
Article in Journal/Newspaper |
author |
Noussa R. El Basha Huda Marzouk May M. Sherif Amani A. El Kholy |
author_facet |
Noussa R. El Basha Huda Marzouk May M. Sherif Amani A. El Kholy |
author_sort |
Noussa R. El Basha |
title |
Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
title_short |
Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
title_full |
Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
title_fullStr |
Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
title_full_unstemmed |
Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
title_sort |
prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy |
publisher |
SpringerOpen |
publishDate |
2019 |
url |
https://doi.org/10.1186/s42506-019-0015-8 https://doaj.org/article/f234b544e72248c58c4157b22d81c8bd |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of the Egyptian Public Health Association, Vol 94, Iss 1, Pp 1-6 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s42506-019-0015-8 https://doaj.org/toc/2090-262X doi:10.1186/s42506-019-0015-8 2090-262X https://doaj.org/article/f234b544e72248c58c4157b22d81c8bd |
op_doi |
https://doi.org/10.1186/s42506-019-0015-8 |
container_title |
Journal of the Egyptian Public Health Association |
container_volume |
94 |
container_issue |
1 |
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1766343064652087296 |