Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018.
Background Intestinal parasites such as Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica can cause severe diarrhea, especially among children in developing countries. This study aims to determine the frequency of Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica in child...
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ftdoajarticles:oai:doaj.org/article:f1c452a2f11e4c3baaee588beac6e295 2023-05-15T15:14:09+02:00 Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. Adilson Fernando Loforte Bauhofer Idalécia Cossa-Moiane Selma Marques Esperança L Guimarães Benilde Munlela Elda Anapakala Jorfélia J Chilaúle Marta Cassocera Jerónimo S Langa Assucênio Chissaque Júlia Sambo Lena Manhique-Coutinho Diocreciano Matias Bero Timothy A Kellogg Nilsa de Deus 2020-04-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008195 https://doaj.org/article/f1c452a2f11e4c3baaee588beac6e295 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008195 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008195 https://doaj.org/article/f1c452a2f11e4c3baaee588beac6e295 PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0008195 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008195 2022-12-31T05:55:01Z Background Intestinal parasites such as Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica can cause severe diarrhea, especially among children in developing countries. This study aims to determine the frequency of Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica in children with diarrhea and identify risk factors for infection. Methodology We conducted a cross-sectional study in children aged 0-168 months hospitalized with diarrhea in three regions of Mozambique, from June 2014 to January 2018. Following consent, caretakers were interviewed and a single stool specimen was collected from each child to diagnose Cryptosporidium spp., G. lamblia and E. histolytica using commercial immune-enzymatic assay (TechLab, Inc, Blacksburg, VA, USA). Anthropometric data were collected from the clinical reports. Multivariable logistic regression models were built to identify risk factors for Cryptosporidium spp. and G. lamblia infection. Results Twenty-one percent of all specimens (212/1008) presented at least one parasitic infection. Cryptosporidium spp. infection was the most common 12.0% (118/985), followed by G. lamblia 9.7% (95/983) and E. histolytica 2.0% (20/1004). Risk factors for infection by Cryptosporidium spp. were: provenience (children from Nampula province showed the highest risk, OR: 8.176; CI: 1.916-34.894; p-value < 0.01); animal contact (children with animal contact had a protective effect OR: 0.627; CI: 0.398-0.986; p-value < 0.05); underweight (children severely underweight showed a risk of 2.309; CI: 1.310-4.069; p-value < 0.05). Risk factors for infection by G. lamblia were: age (group with highest risk, 60-168 months (OR: 2.322; CI: 1.000-5.393, p-value > 0.05)); and living in a household with five or more members (OR: 2.141; CI: 1.286-3.565, p-value < 0.01). Conclusions Parasitic infection is common among children with diarrhea. Routine testing, standard treatment, and assessment for risk exposure of children with diarrhea should be implemented at health ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 4 e0008195 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Adilson Fernando Loforte Bauhofer Idalécia Cossa-Moiane Selma Marques Esperança L Guimarães Benilde Munlela Elda Anapakala Jorfélia J Chilaúle Marta Cassocera Jerónimo S Langa Assucênio Chissaque Júlia Sambo Lena Manhique-Coutinho Diocreciano Matias Bero Timothy A Kellogg Nilsa de Deus Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Intestinal parasites such as Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica can cause severe diarrhea, especially among children in developing countries. This study aims to determine the frequency of Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica in children with diarrhea and identify risk factors for infection. Methodology We conducted a cross-sectional study in children aged 0-168 months hospitalized with diarrhea in three regions of Mozambique, from June 2014 to January 2018. Following consent, caretakers were interviewed and a single stool specimen was collected from each child to diagnose Cryptosporidium spp., G. lamblia and E. histolytica using commercial immune-enzymatic assay (TechLab, Inc, Blacksburg, VA, USA). Anthropometric data were collected from the clinical reports. Multivariable logistic regression models were built to identify risk factors for Cryptosporidium spp. and G. lamblia infection. Results Twenty-one percent of all specimens (212/1008) presented at least one parasitic infection. Cryptosporidium spp. infection was the most common 12.0% (118/985), followed by G. lamblia 9.7% (95/983) and E. histolytica 2.0% (20/1004). Risk factors for infection by Cryptosporidium spp. were: provenience (children from Nampula province showed the highest risk, OR: 8.176; CI: 1.916-34.894; p-value < 0.01); animal contact (children with animal contact had a protective effect OR: 0.627; CI: 0.398-0.986; p-value < 0.05); underweight (children severely underweight showed a risk of 2.309; CI: 1.310-4.069; p-value < 0.05). Risk factors for infection by G. lamblia were: age (group with highest risk, 60-168 months (OR: 2.322; CI: 1.000-5.393, p-value > 0.05)); and living in a household with five or more members (OR: 2.141; CI: 1.286-3.565, p-value < 0.01). Conclusions Parasitic infection is common among children with diarrhea. Routine testing, standard treatment, and assessment for risk exposure of children with diarrhea should be implemented at health ... |
format |
Article in Journal/Newspaper |
author |
Adilson Fernando Loforte Bauhofer Idalécia Cossa-Moiane Selma Marques Esperança L Guimarães Benilde Munlela Elda Anapakala Jorfélia J Chilaúle Marta Cassocera Jerónimo S Langa Assucênio Chissaque Júlia Sambo Lena Manhique-Coutinho Diocreciano Matias Bero Timothy A Kellogg Nilsa de Deus |
author_facet |
Adilson Fernando Loforte Bauhofer Idalécia Cossa-Moiane Selma Marques Esperança L Guimarães Benilde Munlela Elda Anapakala Jorfélia J Chilaúle Marta Cassocera Jerónimo S Langa Assucênio Chissaque Júlia Sambo Lena Manhique-Coutinho Diocreciano Matias Bero Timothy A Kellogg Nilsa de Deus |
author_sort |
Adilson Fernando Loforte Bauhofer |
title |
Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. |
title_short |
Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. |
title_full |
Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. |
title_fullStr |
Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. |
title_full_unstemmed |
Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018. |
title_sort |
intestinal protozoan infections among children 0-168 months with diarrhea in mozambique: june 2014 - january 2018. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008195 https://doaj.org/article/f1c452a2f11e4c3baaee588beac6e295 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0008195 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008195 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008195 https://doaj.org/article/f1c452a2f11e4c3baaee588beac6e295 |
op_doi |
https://doi.org/10.1371/journal.pntd.0008195 |
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PLOS Neglected Tropical Diseases |
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14 |
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4 |
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e0008195 |
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1766344635815297024 |