Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study.
BACKGROUND:Against the background of the international public health emergency related to the Ebola outbreak in the Democratic Republic of Congo, in addition to other recent large Ebola epidemics, the issue of transmission due to viral persistence from survivors' body fluids is becoming increas...
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ftdoajarticles:oai:doaj.org/article:f1aacc402dd9425aba5c6cd5cd9df550 2023-05-15T15:15:20+02:00 Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. Ruth Kutalek Florence Baingana Stephen Sevalie Nathalie Broutet Anna Thorson 2020-05-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008327 https://doaj.org/article/f1aacc402dd9425aba5c6cd5cd9df550 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008327 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008327 https://doaj.org/article/f1aacc402dd9425aba5c6cd5cd9df550 PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008327 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008327 2022-12-31T09:21:49Z BACKGROUND:Against the background of the international public health emergency related to the Ebola outbreak in the Democratic Republic of Congo, in addition to other recent large Ebola epidemics, the issue of transmission due to viral persistence from survivors' body fluids is becoming increasingly urgent. Clinical research in which body fluids play a role is critical and semen testing programs are part of the suggested response to the outbreak. Broad acceptance and understanding of testing programs and research, often in resource poor settings, is essential for the success and sustainability of clinical studies and an accurate epidemic response. Study participants' perceptions on the collection of body fluids are therefore relevant for the programmatic planning and implementation of clinical studies. STUDY AIM AND METHODS:In this qualitative study we aimed to explore the perceptions on bio-sampling in the Sierra Leone Ebola Virus Persistence Study (SLEVP study). We were interested to understand how norms on gender and sexuality related to perceptions and experiences of study participants and staff, specifically, in what way perceptions of the body, on intimacy and on body fluids related to the study process. We purposively sampled former study participants for in-depth interviews and focus-group discussions. We conducted 56 in-depth interviews and eight focus group discussions with 93 participants. In a participatory approach we included study participants in the analysis of data. RESULTS:Overall the SLEVP study was well perceived by study participants and study staff. Study participants conceived the testing of their body fluids positively and saw it as a useful means to know their status. However, some study participants were ambivalent and sometimes reluctant towards sampling of certain body fluids (especially semen, blood and vaginal fluid) due to religious or cultural reasons. Self-sampling was described by study participants as a highly unusual phenomenon. Several narratives were related to the loss of ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 5 e0008327 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Ruth Kutalek Florence Baingana Stephen Sevalie Nathalie Broutet Anna Thorson Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Against the background of the international public health emergency related to the Ebola outbreak in the Democratic Republic of Congo, in addition to other recent large Ebola epidemics, the issue of transmission due to viral persistence from survivors' body fluids is becoming increasingly urgent. Clinical research in which body fluids play a role is critical and semen testing programs are part of the suggested response to the outbreak. Broad acceptance and understanding of testing programs and research, often in resource poor settings, is essential for the success and sustainability of clinical studies and an accurate epidemic response. Study participants' perceptions on the collection of body fluids are therefore relevant for the programmatic planning and implementation of clinical studies. STUDY AIM AND METHODS:In this qualitative study we aimed to explore the perceptions on bio-sampling in the Sierra Leone Ebola Virus Persistence Study (SLEVP study). We were interested to understand how norms on gender and sexuality related to perceptions and experiences of study participants and staff, specifically, in what way perceptions of the body, on intimacy and on body fluids related to the study process. We purposively sampled former study participants for in-depth interviews and focus-group discussions. We conducted 56 in-depth interviews and eight focus group discussions with 93 participants. In a participatory approach we included study participants in the analysis of data. RESULTS:Overall the SLEVP study was well perceived by study participants and study staff. Study participants conceived the testing of their body fluids positively and saw it as a useful means to know their status. However, some study participants were ambivalent and sometimes reluctant towards sampling of certain body fluids (especially semen, blood and vaginal fluid) due to religious or cultural reasons. Self-sampling was described by study participants as a highly unusual phenomenon. Several narratives were related to the loss of ... |
format |
Article in Journal/Newspaper |
author |
Ruth Kutalek Florence Baingana Stephen Sevalie Nathalie Broutet Anna Thorson |
author_facet |
Ruth Kutalek Florence Baingana Stephen Sevalie Nathalie Broutet Anna Thorson |
author_sort |
Ruth Kutalek |
title |
Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. |
title_short |
Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. |
title_full |
Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. |
title_fullStr |
Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. |
title_full_unstemmed |
Perceptions on the collection of body fluids for research on persistence of Ebola virus: A qualitative study. |
title_sort |
perceptions on the collection of body fluids for research on persistence of ebola virus: a qualitative study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008327 https://doaj.org/article/f1aacc402dd9425aba5c6cd5cd9df550 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008327 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008327 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008327 https://doaj.org/article/f1aacc402dd9425aba5c6cd5cd9df550 |
op_doi |
https://doi.org/10.1371/journal.pntd.0008327 |
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PLOS Neglected Tropical Diseases |
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14 |
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e0008327 |
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