Schistosomal appendicitis: Case series and systematic literature review.
Background Globally, schistosomiasis affects at least 240 million people each year with a high proportion of cases in sub-Saharan Africa. The infection presents a wide range of symptoms mainly at the gastrointestinal and urogenital level. Cases of schistosomiasis-related appendicitis are seldom repo...
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ftdoajarticles:oai:doaj.org/article:f1197d7b4e7a4ef194db3001e5366d7c 2023-05-15T15:15:14+02:00 Schistosomal appendicitis: Case series and systematic literature review. Mateus Zacarias Damiano Pizzol Helder de Miranda Anna Claudia Colangelo Nicola Veronese Lee Smith 2021-06-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0009478 https://doaj.org/article/f1197d7b4e7a4ef194db3001e5366d7c EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0009478 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009478 https://doaj.org/article/f1197d7b4e7a4ef194db3001e5366d7c PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009478 (2021) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles https://doi.org/10.1371/journal.pntd.0009478 2022-12-31T08:01:16Z Background Globally, schistosomiasis affects at least 240 million people each year with a high proportion of cases in sub-Saharan Africa. The infection presents a wide range of symptoms mainly at the gastrointestinal and urogenital level. Cases of schistosomiasis-related appendicitis are seldom reported. The aim of the present study is to identify the prevalence of schistosomiasis-related appendicitis in Beira, Mozambique and compare to global prevalence. Methods We retrospectively reviewed all cases of appendicitis recorded from January 2017 to March 2020 at a single pathology department located in Beira in order to assess the prevalence of schistosomiasis. Moreover, we performed a systematic review on the prevalence of schistosomiasis-related appendicitis in all countries. Findings A total of 145 appendicitis cases in Beira showed a 13.1% prevalence of schistosomal-related appendicitis. The mean age of patients was 29.1 years, and 14 (73.7%) were male. The systematic review identified 20 studies with 34,790 inpatients with schistosomiasis-related appendicitis with a global prevalence of 1.31% (95% confidence interval (CI): 0.72 to 2.06); a high heterogeneity (I2 = 96.0%) was observed. Studies carried out in Africa reported a significantly higher prevalence of schistosomiasis-related appendicitis (2.75%; 95% CI: 1.28 to 4.68) than those in Middle East (0.49%; 95% CI: 0.18 to 0.95) (p for interaction < 0.0001). Conclusions Schistosomiasis infection should be considered as possible cause of appendicitis not only in endemic areas but also in developed countries. Considering that prevention is the best way to control the infection, more efforts should be put in place in order to increase the prevention coverage and avoid the cascading implications for health. This is even more so important in this Coronavirus Disease 2019 (COVID-19) era where the majority of attention and funds are used to fight the pandemic. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 15 6 e0009478 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Mateus Zacarias Damiano Pizzol Helder de Miranda Anna Claudia Colangelo Nicola Veronese Lee Smith Schistosomal appendicitis: Case series and systematic literature review. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Globally, schistosomiasis affects at least 240 million people each year with a high proportion of cases in sub-Saharan Africa. The infection presents a wide range of symptoms mainly at the gastrointestinal and urogenital level. Cases of schistosomiasis-related appendicitis are seldom reported. The aim of the present study is to identify the prevalence of schistosomiasis-related appendicitis in Beira, Mozambique and compare to global prevalence. Methods We retrospectively reviewed all cases of appendicitis recorded from January 2017 to March 2020 at a single pathology department located in Beira in order to assess the prevalence of schistosomiasis. Moreover, we performed a systematic review on the prevalence of schistosomiasis-related appendicitis in all countries. Findings A total of 145 appendicitis cases in Beira showed a 13.1% prevalence of schistosomal-related appendicitis. The mean age of patients was 29.1 years, and 14 (73.7%) were male. The systematic review identified 20 studies with 34,790 inpatients with schistosomiasis-related appendicitis with a global prevalence of 1.31% (95% confidence interval (CI): 0.72 to 2.06); a high heterogeneity (I2 = 96.0%) was observed. Studies carried out in Africa reported a significantly higher prevalence of schistosomiasis-related appendicitis (2.75%; 95% CI: 1.28 to 4.68) than those in Middle East (0.49%; 95% CI: 0.18 to 0.95) (p for interaction < 0.0001). Conclusions Schistosomiasis infection should be considered as possible cause of appendicitis not only in endemic areas but also in developed countries. Considering that prevention is the best way to control the infection, more efforts should be put in place in order to increase the prevention coverage and avoid the cascading implications for health. This is even more so important in this Coronavirus Disease 2019 (COVID-19) era where the majority of attention and funds are used to fight the pandemic. |
format |
Article in Journal/Newspaper |
author |
Mateus Zacarias Damiano Pizzol Helder de Miranda Anna Claudia Colangelo Nicola Veronese Lee Smith |
author_facet |
Mateus Zacarias Damiano Pizzol Helder de Miranda Anna Claudia Colangelo Nicola Veronese Lee Smith |
author_sort |
Mateus Zacarias |
title |
Schistosomal appendicitis: Case series and systematic literature review. |
title_short |
Schistosomal appendicitis: Case series and systematic literature review. |
title_full |
Schistosomal appendicitis: Case series and systematic literature review. |
title_fullStr |
Schistosomal appendicitis: Case series and systematic literature review. |
title_full_unstemmed |
Schistosomal appendicitis: Case series and systematic literature review. |
title_sort |
schistosomal appendicitis: case series and systematic literature review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doi.org/10.1371/journal.pntd.0009478 https://doaj.org/article/f1197d7b4e7a4ef194db3001e5366d7c |
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Arctic |
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Arctic |
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Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009478 (2021) |
op_relation |
https://doi.org/10.1371/journal.pntd.0009478 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009478 https://doaj.org/article/f1197d7b4e7a4ef194db3001e5366d7c |
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https://doi.org/10.1371/journal.pntd.0009478 |
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PLOS Neglected Tropical Diseases |
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e0009478 |
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