Fatal case of human rabies infection: A case report
Rationale: Rabies, as an acute viral disease of the mammal’s central nervous system (CNS), with a high mortality rate, is transmitted to humans through the bite of a rabid animals, especially canine and feline. Patient concerns: An Afghan man, aged 50 years was bitten by a fox in a farm around the Q...
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ftdoajarticles:oai:doaj.org/article:f10128144b464caca3ba1dc75e26b8db 2023-05-15T15:14:07+02:00 Fatal case of human rabies infection: A case report Seyed Abbas Hosseinalipour Faranak Firoozfar Abedin Saghafipour Nazanin Ziasheikholeslami 2019-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.271293 https://doaj.org/article/f10128144b464caca3ba1dc75e26b8db EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2019;volume=12;issue=11;spage=528;epage=530;aulast=Hosseinalipour https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.271293 https://doaj.org/article/f10128144b464caca3ba1dc75e26b8db Asian Pacific Journal of Tropical Medicine, Vol 12, Iss 11, Pp 528-530 (2019) animal bite preventive measures rabies iran Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.4103/1995-7645.271293 2022-12-31T12:36:41Z Rationale: Rabies, as an acute viral disease of the mammal’s central nervous system (CNS), with a high mortality rate, is transmitted to humans through the bite of a rabid animals, especially canine and feline. Patient concerns: An Afghan man, aged 50 years was bitten by a fox in a farm around the Qom-Tehran road, Central Iran in 2018. The patient visited the doctor after the bite, however the period between incidence and hospital visit was not established and no indication was given whether the bite site injury was thoroughly washed. The patient was neither referred to the health center for vaccination (post-exposure prophylaxis) nor an effective therapeutic measures was applied. Forty-five days post-exposure, the patient presented with symptoms such as headache, fever, tingling and burning sensation and was referred to the Centers for Disease Control and Prevention (CDC) unit of Qom Provincial Health Center. Diagnosis: Rabies infection. Interventions: Forty-five days after the animal bite, in CDC of Qom Health Center, he received rabies post-exposure prophylaxis treatment was referred to an infectious diseases physician. Based on the history of animal bites, the patient was classified as probable case of rabies. The clinical symptoms of rabies appeared in patient after hospitalization. Outcomes: Ultimately the patient died in hospital 4 days after hospitalization (50 days after the occurrence of animal bite). After referring the patient to the CDC, the patient’s saliva (0.5-1 mL) was sampled three times every 3-6 hours and tested by PCR. Human rabies was confirmed by Department of Virology in the Pasteur Institute of Iran. Lessons: Physicians and clinicians have responsibilities to be critical in observations and take prompt actions in case of animal bites, as rabies usually develops within 7 to 14 days, and delayed intervention after the onset of symptoms, vaccine and serum injections cannot lead to the survival of the patient. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pasteur ENVELOPE(140.099,140.099,-66.625,-66.625) Asian Pacific Journal of Tropical Medicine 12 11 528 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
animal bite preventive measures rabies iran Arctic medicine. Tropical medicine RC955-962 |
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animal bite preventive measures rabies iran Arctic medicine. Tropical medicine RC955-962 Seyed Abbas Hosseinalipour Faranak Firoozfar Abedin Saghafipour Nazanin Ziasheikholeslami Fatal case of human rabies infection: A case report |
topic_facet |
animal bite preventive measures rabies iran Arctic medicine. Tropical medicine RC955-962 |
description |
Rationale: Rabies, as an acute viral disease of the mammal’s central nervous system (CNS), with a high mortality rate, is transmitted to humans through the bite of a rabid animals, especially canine and feline. Patient concerns: An Afghan man, aged 50 years was bitten by a fox in a farm around the Qom-Tehran road, Central Iran in 2018. The patient visited the doctor after the bite, however the period between incidence and hospital visit was not established and no indication was given whether the bite site injury was thoroughly washed. The patient was neither referred to the health center for vaccination (post-exposure prophylaxis) nor an effective therapeutic measures was applied. Forty-five days post-exposure, the patient presented with symptoms such as headache, fever, tingling and burning sensation and was referred to the Centers for Disease Control and Prevention (CDC) unit of Qom Provincial Health Center. Diagnosis: Rabies infection. Interventions: Forty-five days after the animal bite, in CDC of Qom Health Center, he received rabies post-exposure prophylaxis treatment was referred to an infectious diseases physician. Based on the history of animal bites, the patient was classified as probable case of rabies. The clinical symptoms of rabies appeared in patient after hospitalization. Outcomes: Ultimately the patient died in hospital 4 days after hospitalization (50 days after the occurrence of animal bite). After referring the patient to the CDC, the patient’s saliva (0.5-1 mL) was sampled three times every 3-6 hours and tested by PCR. Human rabies was confirmed by Department of Virology in the Pasteur Institute of Iran. Lessons: Physicians and clinicians have responsibilities to be critical in observations and take prompt actions in case of animal bites, as rabies usually develops within 7 to 14 days, and delayed intervention after the onset of symptoms, vaccine and serum injections cannot lead to the survival of the patient. |
format |
Article in Journal/Newspaper |
author |
Seyed Abbas Hosseinalipour Faranak Firoozfar Abedin Saghafipour Nazanin Ziasheikholeslami |
author_facet |
Seyed Abbas Hosseinalipour Faranak Firoozfar Abedin Saghafipour Nazanin Ziasheikholeslami |
author_sort |
Seyed Abbas Hosseinalipour |
title |
Fatal case of human rabies infection: A case report |
title_short |
Fatal case of human rabies infection: A case report |
title_full |
Fatal case of human rabies infection: A case report |
title_fullStr |
Fatal case of human rabies infection: A case report |
title_full_unstemmed |
Fatal case of human rabies infection: A case report |
title_sort |
fatal case of human rabies infection: a case report |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2019 |
url |
https://doi.org/10.4103/1995-7645.271293 https://doaj.org/article/f10128144b464caca3ba1dc75e26b8db |
long_lat |
ENVELOPE(140.099,140.099,-66.625,-66.625) |
geographic |
Arctic Pasteur |
geographic_facet |
Arctic Pasteur |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 12, Iss 11, Pp 528-530 (2019) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2019;volume=12;issue=11;spage=528;epage=530;aulast=Hosseinalipour https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.271293 https://doaj.org/article/f10128144b464caca3ba1dc75e26b8db |
op_doi |
https://doi.org/10.4103/1995-7645.271293 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
12 |
container_issue |
11 |
container_start_page |
528 |
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1766344618370138112 |