FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS
Goal of the study: to investigate the changes in ventilation and gas exchange function of the lungs before and after 1-1.5 months after installation of endobronchial valve (EV) aimed at cavity healing in pulmonary destructive tuberculosis patients.Materials and methods. 74 HIV negative patients in t...
Published in: | Tuberculosis and Lung Diseases |
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Language: | Russian |
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New Terra Publishing House
2016
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Online Access: | https://doi.org/10.21292/2075-1230-2016-94-9-30-38 https://doaj.org/article/f078896471a04ed288e3b231cf198e31 |
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ftdoajarticles:oai:doaj.org/article:f078896471a04ed288e3b231cf198e31 2023-10-09T21:50:41+02:00 FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS L. A. Popova E. A. Shergina O. V. Lovacheva T. R. Bagdasaryan N. A. Chernykh V. B. Nefedov 2016-09-01T00:00:00Z https://doi.org/10.21292/2075-1230-2016-94-9-30-38 https://doaj.org/article/f078896471a04ed288e3b231cf198e31 RU rus New Terra Publishing House https://www.tibl-journal.com/jour/article/view/926 https://doaj.org/toc/2075-1230 https://doaj.org/toc/2542-1506 2075-1230 2542-1506 doi:10.21292/2075-1230-2016-94-9-30-38 https://doaj.org/article/f078896471a04ed288e3b231cf198e31 Туберкулез и болезни лёгких, Vol 94, Iss 9, Pp 30-38 (2016) деструктивный туберкулез легких клапанная бронхоблокация вентиляционная функция легких газооменная функция легких эндобронхиальный клапан Diseases of the respiratory system RC705-779 article 2016 ftdoajarticles https://doi.org/10.21292/2075-1230-2016-94-9-30-38 2023-09-10T00:41:28Z Goal of the study: to investigate the changes in ventilation and gas exchange function of the lungs before and after 1-1.5 months after installation of endobronchial valve (EV) aimed at cavity healing in pulmonary destructive tuberculosis patients.Materials and methods. 74 HIV negative patients in the age from 18 to 61 years old suffering from destructive pulmonary tuberculosis were examined. The changes in the pulmonary ventilation capacity (VC, FEV1 , FEV1 /VC%, PEF, MEF25,75) and blood gases (РаО2 , РаСО2, SaО2 %) before and in 4-6 weeks after EV installation have been studied.Results. After 1-1.5 months after EV installation no significant changes in the pulmonary ventilation function were found in 62.2% of patients, 43.2% of patients demonstrated no significant changes in gas exchange function and there were certain changes in the remaining patients. Reduction of pulmonary ventilation capacity due to large bronchi obstruction, restrictive changes and pulmonary gas exchange were manifested through reduction of FEV1 in 18.9% (95% CI 11.6-29.3%) of patients, PEF – in 20.3% (95% CI 12.7-30.8%), VC – in 22.9% (95% CI 14.9%-33.8%) and PaO2 – in 32.4% (95% CI 22.9-43.7%) of patients.Reduction of carbonic acid content in blood was observed in 27.0% (95% CI 18.3-38.1%) of patients. The improvement of gas exchange and ventilation function was the following: VC in 14.9% of patients (95% CI 8.5-24.7%), РаО2 – in 24.3% (95% CI 16.0-35.2%) and SаO2 – in 20.3% (95% CI 12.7-30.8%) of patients. Patients remained stable due to moderate intensity of changes.Frequency of negative and positive functional changes after installation of endobronchial valve for valve bronchial blocking (VBB) varies to some extent depending on the place of EV installation, volume of VBB and dissemination of tuberculous lesions.Lower installation of VBB versus upper one: VC increases more rarely (in 8.3 and 21.6% of patients, p < 0.05 respectively), FEV1 decreases more often (in 41.7 and 13.5% of patients p < 0.05 respectively), VC, PEF, РаО2 ... Article in Journal/Newspaper Carbonic acid Directory of Open Access Journals: DOAJ Articles Tuberculosis and Lung Diseases 94 9 30 38 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
Russian |
topic |
деструктивный туберкулез легких клапанная бронхоблокация вентиляционная функция легких газооменная функция легких эндобронхиальный клапан Diseases of the respiratory system RC705-779 |
spellingShingle |
деструктивный туберкулез легких клапанная бронхоблокация вентиляционная функция легких газооменная функция легких эндобронхиальный клапан Diseases of the respiratory system RC705-779 L. A. Popova E. A. Shergina O. V. Lovacheva T. R. Bagdasaryan N. A. Chernykh V. B. Nefedov FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS |
topic_facet |
деструктивный туберкулез легких клапанная бронхоблокация вентиляционная функция легких газооменная функция легких эндобронхиальный клапан Diseases of the respiratory system RC705-779 |
description |
Goal of the study: to investigate the changes in ventilation and gas exchange function of the lungs before and after 1-1.5 months after installation of endobronchial valve (EV) aimed at cavity healing in pulmonary destructive tuberculosis patients.Materials and methods. 74 HIV negative patients in the age from 18 to 61 years old suffering from destructive pulmonary tuberculosis were examined. The changes in the pulmonary ventilation capacity (VC, FEV1 , FEV1 /VC%, PEF, MEF25,75) and blood gases (РаО2 , РаСО2, SaО2 %) before and in 4-6 weeks after EV installation have been studied.Results. After 1-1.5 months after EV installation no significant changes in the pulmonary ventilation function were found in 62.2% of patients, 43.2% of patients demonstrated no significant changes in gas exchange function and there were certain changes in the remaining patients. Reduction of pulmonary ventilation capacity due to large bronchi obstruction, restrictive changes and pulmonary gas exchange were manifested through reduction of FEV1 in 18.9% (95% CI 11.6-29.3%) of patients, PEF – in 20.3% (95% CI 12.7-30.8%), VC – in 22.9% (95% CI 14.9%-33.8%) and PaO2 – in 32.4% (95% CI 22.9-43.7%) of patients.Reduction of carbonic acid content in blood was observed in 27.0% (95% CI 18.3-38.1%) of patients. The improvement of gas exchange and ventilation function was the following: VC in 14.9% of patients (95% CI 8.5-24.7%), РаО2 – in 24.3% (95% CI 16.0-35.2%) and SаO2 – in 20.3% (95% CI 12.7-30.8%) of patients. Patients remained stable due to moderate intensity of changes.Frequency of negative and positive functional changes after installation of endobronchial valve for valve bronchial blocking (VBB) varies to some extent depending on the place of EV installation, volume of VBB and dissemination of tuberculous lesions.Lower installation of VBB versus upper one: VC increases more rarely (in 8.3 and 21.6% of patients, p < 0.05 respectively), FEV1 decreases more often (in 41.7 and 13.5% of patients p < 0.05 respectively), VC, PEF, РаО2 ... |
format |
Article in Journal/Newspaper |
author |
L. A. Popova E. A. Shergina O. V. Lovacheva T. R. Bagdasaryan N. A. Chernykh V. B. Nefedov |
author_facet |
L. A. Popova E. A. Shergina O. V. Lovacheva T. R. Bagdasaryan N. A. Chernykh V. B. Nefedov |
author_sort |
L. A. Popova |
title |
FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS |
title_short |
FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS |
title_full |
FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS |
title_fullStr |
FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS |
title_full_unstemmed |
FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS |
title_sort |
functional response to endobronchial valve implanting to those suffering from pulmonary destructive tuberculosis |
publisher |
New Terra Publishing House |
publishDate |
2016 |
url |
https://doi.org/10.21292/2075-1230-2016-94-9-30-38 https://doaj.org/article/f078896471a04ed288e3b231cf198e31 |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_source |
Туберкулез и болезни лёгких, Vol 94, Iss 9, Pp 30-38 (2016) |
op_relation |
https://www.tibl-journal.com/jour/article/view/926 https://doaj.org/toc/2075-1230 https://doaj.org/toc/2542-1506 2075-1230 2542-1506 doi:10.21292/2075-1230-2016-94-9-30-38 https://doaj.org/article/f078896471a04ed288e3b231cf198e31 |
op_doi |
https://doi.org/10.21292/2075-1230-2016-94-9-30-38 |
container_title |
Tuberculosis and Lung Diseases |
container_volume |
94 |
container_issue |
9 |
container_start_page |
30 |
op_container_end_page |
38 |
_version_ |
1779313761774993408 |