Detection of cantharidin-related compounds in Mylabris impressa (Coleoptera: Meloidae)

• Published in: Journal of Venomous Animals and Toxins including Tropical Diseases
• Main Authors: M. R. Nikbakhtzadeh, B. Ebramihi
• Format: Article in Journal/Newspaper
• Language: English
• Published: SciELO 2007
• Subjects: Cantharidin; CRC; palasonin; cantharidinimide; blistering beetle; Meloidae; Mylabris; Arctic medicine. Tropical medicine; RC955-962; Toxicology. Poisons; RA1190-1270; Zoology; QL1-991; Arctic
• Online Access: https://doi.org/10.1590/S1678-91992007000300011; https://doaj.org/article/ef6c079682a2418fa4fec25dfb3cecca

Cantharidin is mainly found in the beetle families Meloidae and Oedemeridae (Insecta: Coleoptera) which are the natural producers of this terpene anhydride. Most studies to date have focused on cantharidin distribution in blister beetles, with few reports on recently found cantharidin-related compounds (CRCs). Using gas chromatography-mass spectrometry (GC-MS), the present work reported cantharidin and two CRCs, palasonin and cantharidinimide from Mylabris impressa stillata (Baudi, 1878) which was collected from Toyserkan county, Hamedan Province, Iran. Ionization provided mass spectra with characteristic fragments of cantharidin at m/z 96 and 128, demethylcantharidin at m/z 82 and 114, and cantharidinimide at m/z 70, 96 and 127. This is the first time that cantharidin and the two CRCs are found in the genus Mylabris which in turn is new to the field of venomous insects.