Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle
Due to the fencing of the Przewalski’s gazelle ( Procapra przewalskii ), the microcytic anemia incidence rate continues to increase. The primary pathological symptoms include emaciation, anemia, pica, inappetence, and dyskinesia. To investigate the cause of microcytic anemia ailment in the Przewalsk...
Published in: | Animals |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
MDPI AG
2024
|
Subjects: | |
Online Access: | https://doi.org/10.3390/ani14071114 https://doaj.org/article/ef1ef05a398d4bd5beb3a89e6aea2e5e |
id |
ftdoajarticles:oai:doaj.org/article:ef1ef05a398d4bd5beb3a89e6aea2e5e |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:ef1ef05a398d4bd5beb3a89e6aea2e5e 2024-09-15T17:59:55+00:00 Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle Yang Ran Yuanfeng Li Xiaoyun Shen 2024-04-01T00:00:00Z https://doi.org/10.3390/ani14071114 https://doaj.org/article/ef1ef05a398d4bd5beb3a89e6aea2e5e EN eng MDPI AG https://www.mdpi.com/2076-2615/14/7/1114 https://doaj.org/toc/2076-2615 doi:10.3390/ani14071114 2076-2615 https://doaj.org/article/ef1ef05a398d4bd5beb3a89e6aea2e5e Animals, Vol 14, Iss 7, p 1114 (2024) Przewalski’s gazelle microcytic anemia selenium nutrition copper deprivation the Qinghai–Tibet Plateau Veterinary medicine SF600-1100 Zoology QL1-991 article 2024 ftdoajarticles https://doi.org/10.3390/ani14071114 2024-08-05T17:49:37Z Due to the fencing of the Przewalski’s gazelle ( Procapra przewalskii ), the microcytic anemia incidence rate continues to increase. The primary pathological symptoms include emaciation, anemia, pica, inappetence, and dyskinesia. To investigate the cause of microcytic anemia ailment in the Przewalski’s gazelle, the Upper Buha River Area with an excessive incidence was chosen as the experimental pasture, and the Bird Island Area without microcytic anemia disease was chosen as the control field. Then, the mineral contents in the soil, forage, blood, and liver, as well as the blood routine parameters and biochemical indexes were measured. The findings showed that the experimental pasture had much lower Se content in the soil and forage than the control field ( p < 0.01), while the impacted pasture had significantly higher S content in the forage. The damaged gazelles had considerably lower Se and Cu contents and higher S content in the blood and liver than the healthy gazelles ( p < 0.01). The presences of Hb, HCT, MCV, and MCH were significantly decreased compared to those in healthy gazelles ( p < 0.01). The experimental group had a significantly lower level of GSH-Px activity in their serums compared to the control group ( p < 0.01). In the treatment experiment, ten gazelles from the affected pasture were orally administered CuSO 4 , 6 g/animal once every 10 days for two consecutive times, and all gazelles were successfully cured. Therefore, it is possible that low Se content in the soil induced an increase in the absorption of S content by forage, leading to the deficiency of secondary Cu in the Przewalski’s gazelles, resulting in microcytic anemia. Article in Journal/Newspaper Bird Island Directory of Open Access Journals: DOAJ Articles Animals 14 7 1114 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Przewalski’s gazelle microcytic anemia selenium nutrition copper deprivation the Qinghai–Tibet Plateau Veterinary medicine SF600-1100 Zoology QL1-991 |
spellingShingle |
Przewalski’s gazelle microcytic anemia selenium nutrition copper deprivation the Qinghai–Tibet Plateau Veterinary medicine SF600-1100 Zoology QL1-991 Yang Ran Yuanfeng Li Xiaoyun Shen Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle |
topic_facet |
Przewalski’s gazelle microcytic anemia selenium nutrition copper deprivation the Qinghai–Tibet Plateau Veterinary medicine SF600-1100 Zoology QL1-991 |
description |
Due to the fencing of the Przewalski’s gazelle ( Procapra przewalskii ), the microcytic anemia incidence rate continues to increase. The primary pathological symptoms include emaciation, anemia, pica, inappetence, and dyskinesia. To investigate the cause of microcytic anemia ailment in the Przewalski’s gazelle, the Upper Buha River Area with an excessive incidence was chosen as the experimental pasture, and the Bird Island Area without microcytic anemia disease was chosen as the control field. Then, the mineral contents in the soil, forage, blood, and liver, as well as the blood routine parameters and biochemical indexes were measured. The findings showed that the experimental pasture had much lower Se content in the soil and forage than the control field ( p < 0.01), while the impacted pasture had significantly higher S content in the forage. The damaged gazelles had considerably lower Se and Cu contents and higher S content in the blood and liver than the healthy gazelles ( p < 0.01). The presences of Hb, HCT, MCV, and MCH were significantly decreased compared to those in healthy gazelles ( p < 0.01). The experimental group had a significantly lower level of GSH-Px activity in their serums compared to the control group ( p < 0.01). In the treatment experiment, ten gazelles from the affected pasture were orally administered CuSO 4 , 6 g/animal once every 10 days for two consecutive times, and all gazelles were successfully cured. Therefore, it is possible that low Se content in the soil induced an increase in the absorption of S content by forage, leading to the deficiency of secondary Cu in the Przewalski’s gazelles, resulting in microcytic anemia. |
format |
Article in Journal/Newspaper |
author |
Yang Ran Yuanfeng Li Xiaoyun Shen |
author_facet |
Yang Ran Yuanfeng Li Xiaoyun Shen |
author_sort |
Yang Ran |
title |
Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle |
title_short |
Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle |
title_full |
Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle |
title_fullStr |
Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle |
title_full_unstemmed |
Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski’s Gazelle |
title_sort |
studies of a naturally occurring selenium-induced microcytic anemia in the przewalski’s gazelle |
publisher |
MDPI AG |
publishDate |
2024 |
url |
https://doi.org/10.3390/ani14071114 https://doaj.org/article/ef1ef05a398d4bd5beb3a89e6aea2e5e |
genre |
Bird Island |
genre_facet |
Bird Island |
op_source |
Animals, Vol 14, Iss 7, p 1114 (2024) |
op_relation |
https://www.mdpi.com/2076-2615/14/7/1114 https://doaj.org/toc/2076-2615 doi:10.3390/ani14071114 2076-2615 https://doaj.org/article/ef1ef05a398d4bd5beb3a89e6aea2e5e |
op_doi |
https://doi.org/10.3390/ani14071114 |
container_title |
Animals |
container_volume |
14 |
container_issue |
7 |
container_start_page |
1114 |
_version_ |
1810437038519877632 |