Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages?
Abstract Background Malaria control strategies are designed as a solution for either the whole region or the whole country and are assumed to suit every setting. There is a need to shift from this assumption because transmission may be different from one local setting to another. The aim of this stu...
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ftdoajarticles:oai:doaj.org/article:ed7a0d37135440c483bcf287b6790ad5 2023-05-15T15:13:02+02:00 Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? Louis Valérie R Kyobutungi Catherine Yé Yazoumé Sauerborn Rainer 2007-04-01T00:00:00Z https://doi.org/10.1186/1475-2875-6-46 https://doaj.org/article/ed7a0d37135440c483bcf287b6790ad5 EN eng BMC http://www.malariajournal.com/content/6/1/46 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-6-46 1475-2875 https://doaj.org/article/ed7a0d37135440c483bcf287b6790ad5 Malaria Journal, Vol 6, Iss 1, p 46 (2007) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2007 ftdoajarticles https://doi.org/10.1186/1475-2875-6-46 2022-12-31T13:42:59Z Abstract Background Malaria control strategies are designed as a solution for either the whole region or the whole country and are assumed to suit every setting. There is a need to shift from this assumption because transmission may be different from one local setting to another. The aim of this study was to assess the risk of clinical malaria given the village of residence among under-five children in rural north-western Burkina Faso. Methods 867 children (6–59 months) were randomly selected from four sites. Interviewers visited the children weekly at home over a one-year period and tested them for fever. Children with fever were tested for malaria parasites. An episode of clinical malaria was defined as fever (axillary temperature ≥ 37.5°C) + parasites density ≥ 5,000 parasites/μl. Logistic regression was used to assess the risk of clinical malaria among children at a given site of residence. Results Children accumulated 758 person years (PYs). Overall, 597 episodes of clinical malaria were observed, giving an incidence rate of 0.79 per PY. The risk of clinical malaria varied amongst the four sites. Taking one village as reference the odds ratio for the other three sites ranged from 0.66; 95%CI: 0.44–0.98 to 1.49; 95%CI: 1.10–2.01. Conclusion Malaria control strategies should be designed to fit the local context. The heterogeneity of transmission should be assessed at the district level to allow cost-effective resource allocation that gives priority to locations with high risk. Functional routine health information systems could provide the necessary data for context specific risk assessment. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 6 1 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Louis Valérie R Kyobutungi Catherine Yé Yazoumé Sauerborn Rainer Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria control strategies are designed as a solution for either the whole region or the whole country and are assumed to suit every setting. There is a need to shift from this assumption because transmission may be different from one local setting to another. The aim of this study was to assess the risk of clinical malaria given the village of residence among under-five children in rural north-western Burkina Faso. Methods 867 children (6–59 months) were randomly selected from four sites. Interviewers visited the children weekly at home over a one-year period and tested them for fever. Children with fever were tested for malaria parasites. An episode of clinical malaria was defined as fever (axillary temperature ≥ 37.5°C) + parasites density ≥ 5,000 parasites/μl. Logistic regression was used to assess the risk of clinical malaria among children at a given site of residence. Results Children accumulated 758 person years (PYs). Overall, 597 episodes of clinical malaria were observed, giving an incidence rate of 0.79 per PY. The risk of clinical malaria varied amongst the four sites. Taking one village as reference the odds ratio for the other three sites ranged from 0.66; 95%CI: 0.44–0.98 to 1.49; 95%CI: 1.10–2.01. Conclusion Malaria control strategies should be designed to fit the local context. The heterogeneity of transmission should be assessed at the district level to allow cost-effective resource allocation that gives priority to locations with high risk. Functional routine health information systems could provide the necessary data for context specific risk assessment. |
format |
Article in Journal/Newspaper |
author |
Louis Valérie R Kyobutungi Catherine Yé Yazoumé Sauerborn Rainer |
author_facet |
Louis Valérie R Kyobutungi Catherine Yé Yazoumé Sauerborn Rainer |
author_sort |
Louis Valérie R |
title |
Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? |
title_short |
Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? |
title_full |
Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? |
title_fullStr |
Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? |
title_full_unstemmed |
Micro-epidemiology of Plasmodium falciparum malaria: Is there any difference in transmission risk between neighbouring villages? |
title_sort |
micro-epidemiology of plasmodium falciparum malaria: is there any difference in transmission risk between neighbouring villages? |
publisher |
BMC |
publishDate |
2007 |
url |
https://doi.org/10.1186/1475-2875-6-46 https://doaj.org/article/ed7a0d37135440c483bcf287b6790ad5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 6, Iss 1, p 46 (2007) |
op_relation |
http://www.malariajournal.com/content/6/1/46 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-6-46 1475-2875 https://doaj.org/article/ed7a0d37135440c483bcf287b6790ad5 |
op_doi |
https://doi.org/10.1186/1475-2875-6-46 |
container_title |
Malaria Journal |
container_volume |
6 |
container_issue |
1 |
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1766343644978085888 |