Malaria and its possible control on the island of Príncipe
Abstract Background Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalence curves and thus obtained estimates of the vectorial capacity and of the basic reproductiv...
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ftdoajarticles:oai:doaj.org/article:ecb92dbd726e48a9b3ceec2b48cd5a68 2023-05-15T15:17:10+02:00 Malaria and its possible control on the island of Príncipe Ferreira Conceição Gil Vilfrido Charlwood J Derek Hagmann Reto do Rosário Virgíllo Smith Tom A 2003-06-01T00:00:00Z https://doi.org/10.1186/1475-2875-2-15 https://doaj.org/article/ecb92dbd726e48a9b3ceec2b48cd5a68 EN eng BMC http://www.malariajournal.com/content/2/1/15 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-2-15 1475-2875 https://doaj.org/article/ecb92dbd726e48a9b3ceec2b48cd5a68 Malaria Journal, Vol 2, Iss 1, p 15 (2003) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2003 ftdoajarticles https://doi.org/10.1186/1475-2875-2-15 2022-12-31T05:36:36Z Abstract Background Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalence curves and thus obtained estimates of the vectorial capacity and of the basic reproductive number ( R 0 ) for malaria. Methods A cross-sectional malariological survey was carried out, in mid-1999, in six communities, comprising circa 17% of the total 6,000 population of the island. All houses in these communities were registered and their mode of construction recorded. Thick and thin blood films were prepared from all consenting individuals. Each individual was asked whether they possessed a mosquito net, whether they had slept under a mosquito net the previous night, whether they were allergic to chloroquine, and whether they had visited the main island of São Tomé since the beginning of the year. Outpatient records from March 1999 until the end of December 2000 were also examined and the age and place of residence of diagnosed cases noted. Results 203 (19.8%) of the 1,026 individuals examined were found to be infected with Plasmodium falciparum . By fitting the mathematical model of the Garki project to the age-prevalence curve we estimate that the basic reproductive number, R 0 , on the island is approximately 1.6. Over a period of one year, a total of 1,792 P. falciparum cases reported to an outpatient facility at the island's hospital. Overall, 54% of the people interviewed slept under mosquito nets and were at reduced risk of infection. Conversely, people living in houses with openings between the top of the wall and the roof had higher risk of infection. Conclusion This high incidence suggests that most of the malaria cases on the island attend the hospital and that treatment of these cases is an important factor reducing the effective rate of transmission. Providing that clinical cases are effectively treated, endemic malaria can probably be eliminated from the island mainly by reducing exposure ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Main Island ENVELOPE(-38.220,-38.220,-54.007,-54.007) Malaria Journal 2 1 15 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Ferreira Conceição Gil Vilfrido Charlwood J Derek Hagmann Reto do Rosário Virgíllo Smith Tom A Malaria and its possible control on the island of Príncipe |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalence curves and thus obtained estimates of the vectorial capacity and of the basic reproductive number ( R 0 ) for malaria. Methods A cross-sectional malariological survey was carried out, in mid-1999, in six communities, comprising circa 17% of the total 6,000 population of the island. All houses in these communities were registered and their mode of construction recorded. Thick and thin blood films were prepared from all consenting individuals. Each individual was asked whether they possessed a mosquito net, whether they had slept under a mosquito net the previous night, whether they were allergic to chloroquine, and whether they had visited the main island of São Tomé since the beginning of the year. Outpatient records from March 1999 until the end of December 2000 were also examined and the age and place of residence of diagnosed cases noted. Results 203 (19.8%) of the 1,026 individuals examined were found to be infected with Plasmodium falciparum . By fitting the mathematical model of the Garki project to the age-prevalence curve we estimate that the basic reproductive number, R 0 , on the island is approximately 1.6. Over a period of one year, a total of 1,792 P. falciparum cases reported to an outpatient facility at the island's hospital. Overall, 54% of the people interviewed slept under mosquito nets and were at reduced risk of infection. Conversely, people living in houses with openings between the top of the wall and the roof had higher risk of infection. Conclusion This high incidence suggests that most of the malaria cases on the island attend the hospital and that treatment of these cases is an important factor reducing the effective rate of transmission. Providing that clinical cases are effectively treated, endemic malaria can probably be eliminated from the island mainly by reducing exposure ... |
format |
Article in Journal/Newspaper |
author |
Ferreira Conceição Gil Vilfrido Charlwood J Derek Hagmann Reto do Rosário Virgíllo Smith Tom A |
author_facet |
Ferreira Conceição Gil Vilfrido Charlwood J Derek Hagmann Reto do Rosário Virgíllo Smith Tom A |
author_sort |
Ferreira Conceição |
title |
Malaria and its possible control on the island of Príncipe |
title_short |
Malaria and its possible control on the island of Príncipe |
title_full |
Malaria and its possible control on the island of Príncipe |
title_fullStr |
Malaria and its possible control on the island of Príncipe |
title_full_unstemmed |
Malaria and its possible control on the island of Príncipe |
title_sort |
malaria and its possible control on the island of príncipe |
publisher |
BMC |
publishDate |
2003 |
url |
https://doi.org/10.1186/1475-2875-2-15 https://doaj.org/article/ecb92dbd726e48a9b3ceec2b48cd5a68 |
long_lat |
ENVELOPE(-38.220,-38.220,-54.007,-54.007) |
geographic |
Arctic Main Island |
geographic_facet |
Arctic Main Island |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 2, Iss 1, p 15 (2003) |
op_relation |
http://www.malariajournal.com/content/2/1/15 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-2-15 1475-2875 https://doaj.org/article/ecb92dbd726e48a9b3ceec2b48cd5a68 |
op_doi |
https://doi.org/10.1186/1475-2875-2-15 |
container_title |
Malaria Journal |
container_volume |
2 |
container_issue |
1 |
container_start_page |
15 |
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1766347440101785600 |