Caprine brucellosis: A historically neglected disease with significant impact on public health.
Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact...
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ftdoajarticles:oai:doaj.org/article:eb2cd2664f744b2cb98d7f8e861ffaee 2023-05-15T15:12:38+02:00 Caprine brucellosis: A historically neglected disease with significant impact on public health. Carlos A Rossetti Angela M Arenas-Gamboa Estefanía Maurizio 2017-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005692 https://doaj.org/article/eb2cd2664f744b2cb98d7f8e861ffaee EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5560528?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005692 https://doaj.org/article/eb2cd2664f744b2cb98d7f8e861ffaee PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005692 (2017) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2017 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005692 2022-12-31T09:49:45Z Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact in a flock's productivity. B. melitensis is also the most virulent Brucella species for humans, responsible for a severely debilitating and disabling illness that results in high morbidity with intermittent fever, chills, sweats, weakness, myalgia, abortion, osteoarticular complications, endocarditis, depression, anorexia, and low mortality. Historical observations indicate that goats have been the hosts of B. melitensis for centuries; but around 1905, the Greek physician Themistokles Zammit was able to build the epidemiological link between "Malta fever" and the consumption of goat milk. While the disease has been successfully managed in most industrialized countries, it remains a significant burden on goat and human health in the Mediterranean region, the Middle East, Central and Southeast Asia (including India and China), sub-Saharan Africa, and certain areas in Latin America, where approximately 3.5 billion people live at risk. In this review, we describe a historical evolution of the disease, highlight the current worldwide distribution, and estimate (by simple formula) the approximate costs of brucellosis outbreaks to meat- and milk-producing farms and the economic losses associated with the disease in humans. Successful control leading to eradication of caprine brucellosis in the developing world will require a coordinated Global One Health approach involving active involvement of human and animal health efforts to enhance public health and improve livestock productivity. Article in Journal/Newspaper Arctic Human health Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 11 8 e0005692 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Carlos A Rossetti Angela M Arenas-Gamboa Estefanía Maurizio Caprine brucellosis: A historically neglected disease with significant impact on public health. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact in a flock's productivity. B. melitensis is also the most virulent Brucella species for humans, responsible for a severely debilitating and disabling illness that results in high morbidity with intermittent fever, chills, sweats, weakness, myalgia, abortion, osteoarticular complications, endocarditis, depression, anorexia, and low mortality. Historical observations indicate that goats have been the hosts of B. melitensis for centuries; but around 1905, the Greek physician Themistokles Zammit was able to build the epidemiological link between "Malta fever" and the consumption of goat milk. While the disease has been successfully managed in most industrialized countries, it remains a significant burden on goat and human health in the Mediterranean region, the Middle East, Central and Southeast Asia (including India and China), sub-Saharan Africa, and certain areas in Latin America, where approximately 3.5 billion people live at risk. In this review, we describe a historical evolution of the disease, highlight the current worldwide distribution, and estimate (by simple formula) the approximate costs of brucellosis outbreaks to meat- and milk-producing farms and the economic losses associated with the disease in humans. Successful control leading to eradication of caprine brucellosis in the developing world will require a coordinated Global One Health approach involving active involvement of human and animal health efforts to enhance public health and improve livestock productivity. |
format |
Article in Journal/Newspaper |
author |
Carlos A Rossetti Angela M Arenas-Gamboa Estefanía Maurizio |
author_facet |
Carlos A Rossetti Angela M Arenas-Gamboa Estefanía Maurizio |
author_sort |
Carlos A Rossetti |
title |
Caprine brucellosis: A historically neglected disease with significant impact on public health. |
title_short |
Caprine brucellosis: A historically neglected disease with significant impact on public health. |
title_full |
Caprine brucellosis: A historically neglected disease with significant impact on public health. |
title_fullStr |
Caprine brucellosis: A historically neglected disease with significant impact on public health. |
title_full_unstemmed |
Caprine brucellosis: A historically neglected disease with significant impact on public health. |
title_sort |
caprine brucellosis: a historically neglected disease with significant impact on public health. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2017 |
url |
https://doi.org/10.1371/journal.pntd.0005692 https://doaj.org/article/eb2cd2664f744b2cb98d7f8e861ffaee |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Human health |
genre_facet |
Arctic Human health |
op_source |
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005692 (2017) |
op_relation |
http://europepmc.org/articles/PMC5560528?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005692 https://doaj.org/article/eb2cd2664f744b2cb98d7f8e861ffaee |
op_doi |
https://doi.org/10.1371/journal.pntd.0005692 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
11 |
container_issue |
8 |
container_start_page |
e0005692 |
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1766343294908891136 |