The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia
Piscine orthoreovirus Strain PRV-1 is the causative agent of heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar Linnaeus, 1758). Given its high prevalence in net pen salmon, debate has arisen on whether PRV poses a risk to migratory salmon, especially in British Columbia (...
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ftdoajarticles:oai:doaj.org/article:ead5a5c1e97d400f98bed63f205f5382 2023-05-15T15:30:50+02:00 The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia Emiliano Di Cicco Hugh W. Ferguson Karia H. Kaukinen Angela D. Schulze Shaorong Li Amy Tabata Oliver P. Günther Gideon Mordecai Curtis A. Suttle Kristina M. Miller 2018-06-01T00:00:00Z https://doi.org/10.1139/facets-2018-0008 https://doaj.org/article/ead5a5c1e97d400f98bed63f205f5382 EN eng Canadian Science Publishing http://www.facetsjournal.com/doi/full/10.1139%2Ffacets-2018-0008 https://doaj.org/toc/2371-1671 doi:10.1139/facets-2018-0008 2371-1671 https://doaj.org/article/ead5a5c1e97d400f98bed63f205f5382 FACETS, Vol 3, Pp 599-641 (2018) PRV Atlantic salmon chinook salmon HSMI jaundice/anemia VDD ISH Education L Science Q article 2018 ftdoajarticles https://doi.org/10.1139/facets-2018-0008 2022-12-31T11:56:35Z Piscine orthoreovirus Strain PRV-1 is the causative agent of heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar Linnaeus, 1758). Given its high prevalence in net pen salmon, debate has arisen on whether PRV poses a risk to migratory salmon, especially in British Columbia (BC) where commercially important wild Pacific salmon are in decline. Various strains of PRV have been associated with diseases in Pacific salmon, including erythrocytic inclusion body syndrome (EIBS), HSMI-like disease, and jaundice/anemia in Japan, Norway, Chile and Canada. We examined the developmental pathway of HSMI and jaundice/anemia associated with PRV-1 in farmed Atlantic and chinook (Oncorhynchus tshawytscha (Walbaum, 1792)) salmon in BC, respectively. In situ hybridization localized PRV-1 within developing lesions in both diseases. The two diseases showed dissimilar pathological pathways, with inflammatory lesions in heart and skeletal muscle in Atlantic salmon and degenerative-necrotic lesions in kidney and liver in chinook salmon, plausibly explained by differences in PRV load tolerance in red blood cells. Viral genome sequencing revealed no consistent differences in PRV-1 variants intimately involved in the development of both diseases suggesting that migratory chinook salmon may be at more than a minimal risk of disease from exposure to the high levels of PRV occurring in salmon farms. Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles British Columbia ENVELOPE(-125.003,-125.003,54.000,54.000) Canada Norway Pacific FACETS 3 1 599 641 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
PRV Atlantic salmon chinook salmon HSMI jaundice/anemia VDD ISH Education L Science Q |
spellingShingle |
PRV Atlantic salmon chinook salmon HSMI jaundice/anemia VDD ISH Education L Science Q Emiliano Di Cicco Hugh W. Ferguson Karia H. Kaukinen Angela D. Schulze Shaorong Li Amy Tabata Oliver P. Günther Gideon Mordecai Curtis A. Suttle Kristina M. Miller The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia |
topic_facet |
PRV Atlantic salmon chinook salmon HSMI jaundice/anemia VDD ISH Education L Science Q |
description |
Piscine orthoreovirus Strain PRV-1 is the causative agent of heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar Linnaeus, 1758). Given its high prevalence in net pen salmon, debate has arisen on whether PRV poses a risk to migratory salmon, especially in British Columbia (BC) where commercially important wild Pacific salmon are in decline. Various strains of PRV have been associated with diseases in Pacific salmon, including erythrocytic inclusion body syndrome (EIBS), HSMI-like disease, and jaundice/anemia in Japan, Norway, Chile and Canada. We examined the developmental pathway of HSMI and jaundice/anemia associated with PRV-1 in farmed Atlantic and chinook (Oncorhynchus tshawytscha (Walbaum, 1792)) salmon in BC, respectively. In situ hybridization localized PRV-1 within developing lesions in both diseases. The two diseases showed dissimilar pathological pathways, with inflammatory lesions in heart and skeletal muscle in Atlantic salmon and degenerative-necrotic lesions in kidney and liver in chinook salmon, plausibly explained by differences in PRV load tolerance in red blood cells. Viral genome sequencing revealed no consistent differences in PRV-1 variants intimately involved in the development of both diseases suggesting that migratory chinook salmon may be at more than a minimal risk of disease from exposure to the high levels of PRV occurring in salmon farms. |
format |
Article in Journal/Newspaper |
author |
Emiliano Di Cicco Hugh W. Ferguson Karia H. Kaukinen Angela D. Schulze Shaorong Li Amy Tabata Oliver P. Günther Gideon Mordecai Curtis A. Suttle Kristina M. Miller |
author_facet |
Emiliano Di Cicco Hugh W. Ferguson Karia H. Kaukinen Angela D. Schulze Shaorong Li Amy Tabata Oliver P. Günther Gideon Mordecai Curtis A. Suttle Kristina M. Miller |
author_sort |
Emiliano Di Cicco |
title |
The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia |
title_short |
The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia |
title_full |
The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia |
title_fullStr |
The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia |
title_full_unstemmed |
The same strain of Piscine orthoreovirus (PRV-1) is involved in the development of different, but related, diseases in Atlantic and Pacific Salmon in British Columbia |
title_sort |
same strain of piscine orthoreovirus (prv-1) is involved in the development of different, but related, diseases in atlantic and pacific salmon in british columbia |
publisher |
Canadian Science Publishing |
publishDate |
2018 |
url |
https://doi.org/10.1139/facets-2018-0008 https://doaj.org/article/ead5a5c1e97d400f98bed63f205f5382 |
long_lat |
ENVELOPE(-125.003,-125.003,54.000,54.000) |
geographic |
British Columbia Canada Norway Pacific |
geographic_facet |
British Columbia Canada Norway Pacific |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
FACETS, Vol 3, Pp 599-641 (2018) |
op_relation |
http://www.facetsjournal.com/doi/full/10.1139%2Ffacets-2018-0008 https://doaj.org/toc/2371-1671 doi:10.1139/facets-2018-0008 2371-1671 https://doaj.org/article/ead5a5c1e97d400f98bed63f205f5382 |
op_doi |
https://doi.org/10.1139/facets-2018-0008 |
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FACETS |
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3 |
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1 |
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599 |
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641 |
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1766361304148213760 |