Interruption of persistent exposure to leprosy combined or not with recent BCG vaccination enhances the response to Mycobacterium leprae specific antigens.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Fernanda Marques de Carvalho, Luciana Silva Rodrigues, Nádia Cristina Duppre, Iris Maria Peixoto Alvim, Marcelo Ribeiro-Alves, Roberta Olmo Pinheiro, Euzenir Nunes Sarno, Maria Cristina Vidal Pessolani, Geraldo Moura Batista Pereira
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2017
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Calmette
• Online Access: https://doi.org/10.1371/journal.pntd.0005560; https://doaj.org/article/ea233d21d7664dcbb930d8ed56792bc5

Household contacts of multibacillary leprosy patients (HCMB) constitute the group of individuals at the highest risk of developing leprosy. Early diagnosis and treatment of their index cases combined with Bacille Calmette-Guerin (BCG) immunization remain important strategies adopted in Brazil to pre...