Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH
This document presents the most recent update of recommendations from the Department of Health and Human Services of the United States of America concerning the antiretroviral treatment of adolescents and adults who are infected with human immunodeficiency virus (HIV). Among the subjects covered in...
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ftdoajarticles:oai:doaj.org/article:ea1bb756004c4b88a665dbe967955b46 2023-05-15T15:13:20+02:00 Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH 2001-09-01T00:00:00Z https://doi.org/10.1590/s1020-49892001000900016 https://doaj.org/article/ea1bb756004c4b88a665dbe967955b46 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892001000900016&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49892001000900016 https://doaj.org/article/ea1bb756004c4b88a665dbe967955b46 Revista Panamericana de Salud Pública, Vol 10, Iss 3, Pp 202-216 (2001) Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2001 ftdoajarticles https://doi.org/10.1590/s1020-49892001000900016 2022-12-30T22:04:36Z This document presents the most recent update of recommendations from the Department of Health and Human Services of the United States of America concerning the antiretroviral treatment of adolescents and adults who are infected with human immunodeficiency virus (HIV). Among the subjects covered in the document are assessment tests for the viral load, the CD4+ T cell count, and resistance to antiretrovirals; when to begin treatment and with which drugs; when to change treatment and the therapeutic options in that situation; aspects of treating adolescents and pregnant women; treatment adherence; and the drugs' principal side effects. Treatment is indicated for all patients with acute HIV infection, in those who have seroconverted in the preceding 6 months, and in symptomatic patients. With asymptomatic patients, the need for treatment depends on several real or potential risks and benefits. Treatment is usually indicated for asymptomatic individuals with CD4+ T cell counts of < 350/mm³ or with plasma HIV RNA > 55 000 copies/mL with the reverse transcriptase polymerase chain reaction test. Once treatment has begun, goals should include a maximum and durable suppression of the viral load, restoring or maintaining immune function, improving the quality of life, and reducing HIV-related morbidity and mortality. Treatment results are assessed mainly in terms of the plasma HIV RNA level, which should be undetectable (< 50 copies/mL) after 4 to 6 months of treatment. Treatment failure after that period of time can be due to poor treatment adherence, drugs being incompletely suppressive, viral resistance, or other poorly known factors. Treatment should be changed if it fails despite good adherence. This change should be based on a complete analysis of the patient's therapeutic history and on the results of resistance tests. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista Panamericana de Salud Pública 10 3 202 216 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
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English Spanish Portuguese |
topic |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH |
topic_facet |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
This document presents the most recent update of recommendations from the Department of Health and Human Services of the United States of America concerning the antiretroviral treatment of adolescents and adults who are infected with human immunodeficiency virus (HIV). Among the subjects covered in the document are assessment tests for the viral load, the CD4+ T cell count, and resistance to antiretrovirals; when to begin treatment and with which drugs; when to change treatment and the therapeutic options in that situation; aspects of treating adolescents and pregnant women; treatment adherence; and the drugs' principal side effects. Treatment is indicated for all patients with acute HIV infection, in those who have seroconverted in the preceding 6 months, and in symptomatic patients. With asymptomatic patients, the need for treatment depends on several real or potential risks and benefits. Treatment is usually indicated for asymptomatic individuals with CD4+ T cell counts of < 350/mm³ or with plasma HIV RNA > 55 000 copies/mL with the reverse transcriptase polymerase chain reaction test. Once treatment has begun, goals should include a maximum and durable suppression of the viral load, restoring or maintaining immune function, improving the quality of life, and reducing HIV-related morbidity and mortality. Treatment results are assessed mainly in terms of the plasma HIV RNA level, which should be undetectable (< 50 copies/mL) after 4 to 6 months of treatment. Treatment failure after that period of time can be due to poor treatment adherence, drugs being incompletely suppressive, viral resistance, or other poorly known factors. Treatment should be changed if it fails despite good adherence. This change should be based on a complete analysis of the patient's therapeutic history and on the results of resistance tests. |
format |
Article in Journal/Newspaper |
title |
Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH |
title_short |
Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH |
title_full |
Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH |
title_fullStr |
Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH |
title_full_unstemmed |
Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH |
title_sort |
directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por vih |
publisher |
Pan American Health Organization |
publishDate |
2001 |
url |
https://doi.org/10.1590/s1020-49892001000900016 https://doaj.org/article/ea1bb756004c4b88a665dbe967955b46 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 10, Iss 3, Pp 202-216 (2001) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892001000900016&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49892001000900016 https://doaj.org/article/ea1bb756004c4b88a665dbe967955b46 |
op_doi |
https://doi.org/10.1590/s1020-49892001000900016 |
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Revista Panamericana de Salud Pública |
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10 |
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3 |
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202 |
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216 |
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