Gene-Xpert Ultra for the diagnosis of extrapulmonary tuberculosis in children and adolescents

ABSTRACT This prospective study describes the use of Gene-Xpert Ultra for the diagnosis of extrapulmonary tuberculosis (EPTB) in children and adolescents, in Rio de Janeiro, Brazil. Eighteen patients were studied; the final diagnosis of EPTB was established in 13 (72%). Gene-Xpert Ultra results show...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Rafaela Baroni Aurilio, Sidnei Ferreira, Ana Alice Amaral Ibiapina Parente, Maria de Fátima Pombo Sant’Anna, Cláudia Stella Pereira, Thiago da Silva Santos Malaquias, Afrânio Lineu Kritski, Clemax Couto Sant’Anna
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2022
Subjects:
Extrapulmonary tuberculosis
Children
Adolescents
Diagnoses
Real-time PCR
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946202264012
https://doaj.org/article/ea0e9c99d1964d70ac7fab664ca12d77
Description
Summary:ABSTRACT This prospective study describes the use of Gene-Xpert Ultra for the diagnosis of extrapulmonary tuberculosis (EPTB) in children and adolescents, in Rio de Janeiro, Brazil. Eighteen patients were studied; the final diagnosis of EPTB was established in 13 (72%). Gene-Xpert Ultra results showed detection in 10/13 (77%) of EPTB cases (7 of these 10 with trace-positive results). Gene-Xpert Ultra proved to be a promising method for the diagnosis of childhood EPTB.

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