Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats
Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for...
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ftdoajarticles:oai:doaj.org/article:ea060024138941e4b550d41975c50523 2023-05-15T17:59:54+02:00 Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats Anne Goffard Christine Demanche Laurent Arthur Claire Pinçon Johan Michaux Jean Dubuisson 2015-12-01T00:00:00Z https://doi.org/10.3390/v7122937 https://doaj.org/article/ea060024138941e4b550d41975c50523 EN eng MDPI AG http://www.mdpi.com/1999-4915/7/12/2937 https://doaj.org/toc/1999-4915 1999-4915 doi:10.3390/v7122937 https://doaj.org/article/ea060024138941e4b550d41975c50523 Viruses, Vol 7, Iss 12, Pp 6279-6290 (2015) bats alphacoronavirus coronavirus phylogeographic analysis phylogenetic analysis Europe molecular characterization Microbiology QR1-502 article 2015 ftdoajarticles https://doi.org/10.3390/v7122937 2022-12-31T14:57:16Z Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide. Article in Journal/Newspaper Pipistrellus pipistrellus Directory of Open Access Journals: DOAJ Articles Viruses 7 12 6279 6290 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
bats alphacoronavirus coronavirus phylogeographic analysis phylogenetic analysis Europe molecular characterization Microbiology QR1-502 |
spellingShingle |
bats alphacoronavirus coronavirus phylogeographic analysis phylogenetic analysis Europe molecular characterization Microbiology QR1-502 Anne Goffard Christine Demanche Laurent Arthur Claire Pinçon Johan Michaux Jean Dubuisson Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
topic_facet |
bats alphacoronavirus coronavirus phylogeographic analysis phylogenetic analysis Europe molecular characterization Microbiology QR1-502 |
description |
Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide. |
format |
Article in Journal/Newspaper |
author |
Anne Goffard Christine Demanche Laurent Arthur Claire Pinçon Johan Michaux Jean Dubuisson |
author_facet |
Anne Goffard Christine Demanche Laurent Arthur Claire Pinçon Johan Michaux Jean Dubuisson |
author_sort |
Anne Goffard |
title |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_short |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_full |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_fullStr |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_full_unstemmed |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_sort |
alphacoronaviruses detected in french bats are phylogeographically linked to coronaviruses of european bats |
publisher |
MDPI AG |
publishDate |
2015 |
url |
https://doi.org/10.3390/v7122937 https://doaj.org/article/ea060024138941e4b550d41975c50523 |
genre |
Pipistrellus pipistrellus |
genre_facet |
Pipistrellus pipistrellus |
op_source |
Viruses, Vol 7, Iss 12, Pp 6279-6290 (2015) |
op_relation |
http://www.mdpi.com/1999-4915/7/12/2937 https://doaj.org/toc/1999-4915 1999-4915 doi:10.3390/v7122937 https://doaj.org/article/ea060024138941e4b550d41975c50523 |
op_doi |
https://doi.org/10.3390/v7122937 |
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Viruses |
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7 |
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12 |
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6279 |
op_container_end_page |
6290 |
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1766168786044452864 |