Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo

The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44%...

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Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Ana L. R. de Mello, Elizabeth C. Ferreira, Lucy S. Vilas Boas, Claudio S. Pannuti
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 1996
Subjects:
Online Access:https://doi.org/10.1590/S0036-46651996000300001
https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0
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spelling ftdoajarticles:oai:doaj.org/article:e7915dad5738492ebfe41a23b77240d0 2024-09-09T19:28:35+00:00 Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo Ana L. R. de Mello Elizabeth C. Ferreira Lucy S. Vilas Boas Claudio S. Pannuti 1996-06-01T00:00:00Z https://doi.org/10.1590/S0036-46651996000300001 https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651996000300001 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651996000300001 0036-4665 1678-9946 https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0 Revista do Instituto de Medicina Tropical de São Paulo, Vol 38, Iss 3, Pp 165-169 (1996) Cytomegalovirus Day-Care center Epidemiology Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1996 ftdoajarticles https://doi.org/10.1590/S0036-46651996000300001 2024-08-05T17:49:30Z The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. A prevalência de anticorpos e a incidência de infecção por citomegalovírus (CMV) foram estudadas em 98 crianças de 5 a 36 meses de idade que freqüentavam a creche de um hospital universitário em São Paulo. No início do estudo, a prevalência geral de anticorpos para o CMV foi de 44% (43/98). Obteve-se para o isolamento viral, amostras de saliva e/ou urina de 36 das 43 crianças que eram soropositivas, constatando-se que 55,6% das mesmas estavam excretando CMV em um dos materiais. Das 37 crianças inicialmente soronegativas, das quais foi possível obter nova amostra de sangue 6 a 12 meses após, 22 (59,5%) apresentaram soroconversão. A taxa de excreção viral na urina ou saliva nas crianças que soroconverteram foi de 52,4%. Estes resultados indicam que a infecção por CMV foi freqüente e ocorreu precocemente nas crianças que freqüentavam esta creche. Contudo, estudos controlados usando técnicas de epidemiologia molecular são necessários para definir ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 38 3 165 169
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Cytomegalovirus
Day-Care center
Epidemiology
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
spellingShingle Cytomegalovirus
Day-Care center
Epidemiology
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Ana L. R. de Mello
Elizabeth C. Ferreira
Lucy S. Vilas Boas
Claudio S. Pannuti
Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
topic_facet Cytomegalovirus
Day-Care center
Epidemiology
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
description The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. A prevalência de anticorpos e a incidência de infecção por citomegalovírus (CMV) foram estudadas em 98 crianças de 5 a 36 meses de idade que freqüentavam a creche de um hospital universitário em São Paulo. No início do estudo, a prevalência geral de anticorpos para o CMV foi de 44% (43/98). Obteve-se para o isolamento viral, amostras de saliva e/ou urina de 36 das 43 crianças que eram soropositivas, constatando-se que 55,6% das mesmas estavam excretando CMV em um dos materiais. Das 37 crianças inicialmente soronegativas, das quais foi possível obter nova amostra de sangue 6 a 12 meses após, 22 (59,5%) apresentaram soroconversão. A taxa de excreção viral na urina ou saliva nas crianças que soroconverteram foi de 52,4%. Estes resultados indicam que a infecção por CMV foi freqüente e ocorreu precocemente nas crianças que freqüentavam esta creche. Contudo, estudos controlados usando técnicas de epidemiologia molecular são necessários para definir ...
format Article in Journal/Newspaper
author Ana L. R. de Mello
Elizabeth C. Ferreira
Lucy S. Vilas Boas
Claudio S. Pannuti
author_facet Ana L. R. de Mello
Elizabeth C. Ferreira
Lucy S. Vilas Boas
Claudio S. Pannuti
author_sort Ana L. R. de Mello
title Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
title_short Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
title_full Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
title_fullStr Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
title_full_unstemmed Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
title_sort cytomegalovirus infection in a day-care center in the municipality of são paulo infecção por citomegalovírus em creche do município de são paulo
publisher Universidade de São Paulo (USP)
publishDate 1996
url https://doi.org/10.1590/S0036-46651996000300001
https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0
geographic Arctic
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op_source Revista do Instituto de Medicina Tropical de São Paulo, Vol 38, Iss 3, Pp 165-169 (1996)
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https://doaj.org/toc/1678-9946
doi:10.1590/S0036-46651996000300001
0036-4665
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https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0
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