Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo
The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44%...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Universidade de São Paulo (USP)
1996
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ftdoajarticles:oai:doaj.org/article:e7915dad5738492ebfe41a23b77240d0 2024-09-09T19:28:35+00:00 Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo Ana L. R. de Mello Elizabeth C. Ferreira Lucy S. Vilas Boas Claudio S. Pannuti 1996-06-01T00:00:00Z https://doi.org/10.1590/S0036-46651996000300001 https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651996000300001 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651996000300001 0036-4665 1678-9946 https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0 Revista do Instituto de Medicina Tropical de São Paulo, Vol 38, Iss 3, Pp 165-169 (1996) Cytomegalovirus Day-Care center Epidemiology Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1996 ftdoajarticles https://doi.org/10.1590/S0036-46651996000300001 2024-08-05T17:49:30Z The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. A prevalência de anticorpos e a incidência de infecção por citomegalovírus (CMV) foram estudadas em 98 crianças de 5 a 36 meses de idade que freqüentavam a creche de um hospital universitário em São Paulo. No início do estudo, a prevalência geral de anticorpos para o CMV foi de 44% (43/98). Obteve-se para o isolamento viral, amostras de saliva e/ou urina de 36 das 43 crianças que eram soropositivas, constatando-se que 55,6% das mesmas estavam excretando CMV em um dos materiais. Das 37 crianças inicialmente soronegativas, das quais foi possível obter nova amostra de sangue 6 a 12 meses após, 22 (59,5%) apresentaram soroconversão. A taxa de excreção viral na urina ou saliva nas crianças que soroconverteram foi de 52,4%. Estes resultados indicam que a infecção por CMV foi freqüente e ocorreu precocemente nas crianças que freqüentavam esta creche. Contudo, estudos controlados usando técnicas de epidemiologia molecular são necessários para definir ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 38 3 165 169 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Cytomegalovirus Day-Care center Epidemiology Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Cytomegalovirus Day-Care center Epidemiology Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Ana L. R. de Mello Elizabeth C. Ferreira Lucy S. Vilas Boas Claudio S. Pannuti Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo |
topic_facet |
Cytomegalovirus Day-Care center Epidemiology Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. A prevalência de anticorpos e a incidência de infecção por citomegalovírus (CMV) foram estudadas em 98 crianças de 5 a 36 meses de idade que freqüentavam a creche de um hospital universitário em São Paulo. No início do estudo, a prevalência geral de anticorpos para o CMV foi de 44% (43/98). Obteve-se para o isolamento viral, amostras de saliva e/ou urina de 36 das 43 crianças que eram soropositivas, constatando-se que 55,6% das mesmas estavam excretando CMV em um dos materiais. Das 37 crianças inicialmente soronegativas, das quais foi possível obter nova amostra de sangue 6 a 12 meses após, 22 (59,5%) apresentaram soroconversão. A taxa de excreção viral na urina ou saliva nas crianças que soroconverteram foi de 52,4%. Estes resultados indicam que a infecção por CMV foi freqüente e ocorreu precocemente nas crianças que freqüentavam esta creche. Contudo, estudos controlados usando técnicas de epidemiologia molecular são necessários para definir ... |
format |
Article in Journal/Newspaper |
author |
Ana L. R. de Mello Elizabeth C. Ferreira Lucy S. Vilas Boas Claudio S. Pannuti |
author_facet |
Ana L. R. de Mello Elizabeth C. Ferreira Lucy S. Vilas Boas Claudio S. Pannuti |
author_sort |
Ana L. R. de Mello |
title |
Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo |
title_short |
Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo |
title_full |
Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo |
title_fullStr |
Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo |
title_full_unstemmed |
Cytomegalovirus infection in a day-care center in the municipality of São Paulo Infecção por citomegalovírus em creche do município de São Paulo |
title_sort |
cytomegalovirus infection in a day-care center in the municipality of são paulo infecção por citomegalovírus em creche do município de são paulo |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1996 |
url |
https://doi.org/10.1590/S0036-46651996000300001 https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 38, Iss 3, Pp 165-169 (1996) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651996000300001 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651996000300001 0036-4665 1678-9946 https://doaj.org/article/e7915dad5738492ebfe41a23b77240d0 |
op_doi |
https://doi.org/10.1590/S0036-46651996000300001 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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38 |
container_issue |
3 |
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165 |
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169 |
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