First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters
Abstract Background Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outsi...
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ftdoajarticles:oai:doaj.org/article:e76e660be3194f75aa4d14dfde10670e 2023-05-15T15:58:55+02:00 First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters Konstantin Divilov Blaine Schoolfield Benjamin Morga Lionel Dégremont Colleen A. Burge Daniel Mancilla Cortez Carolyn S. Friedman Gary B. Fleener Brett R. Dumbauld Chris Langdon 2019-12-01T00:00:00Z https://doi.org/10.1186/s12863-019-0791-3 https://doaj.org/article/e76e660be3194f75aa4d14dfde10670e EN eng BMC https://doi.org/10.1186/s12863-019-0791-3 https://doaj.org/toc/1471-2156 doi:10.1186/s12863-019-0791-3 1471-2156 https://doaj.org/article/e76e660be3194f75aa4d14dfde10670e BMC Genetics, Vol 20, Iss 1, Pp 1-9 (2019) Ostreid herpesvirus 1 Crassostrea gigas Heritability Breeding Genetics QH426-470 article 2019 ftdoajarticles https://doi.org/10.1186/s12863-019-0791-3 2022-12-30T23:52:46Z Abstract Background Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection. Results Significant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant. Conclusions Future breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. Article in Journal/Newspaper Crassostrea gigas Pacific oyster Directory of Open Access Journals: DOAJ Articles Pacific BMC Genetics 20 1 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Ostreid herpesvirus 1 Crassostrea gigas Heritability Breeding Genetics QH426-470 |
spellingShingle |
Ostreid herpesvirus 1 Crassostrea gigas Heritability Breeding Genetics QH426-470 Konstantin Divilov Blaine Schoolfield Benjamin Morga Lionel Dégremont Colleen A. Burge Daniel Mancilla Cortez Carolyn S. Friedman Gary B. Fleener Brett R. Dumbauld Chris Langdon First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
topic_facet |
Ostreid herpesvirus 1 Crassostrea gigas Heritability Breeding Genetics QH426-470 |
description |
Abstract Background Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection. Results Significant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant. Conclusions Future breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. |
format |
Article in Journal/Newspaper |
author |
Konstantin Divilov Blaine Schoolfield Benjamin Morga Lionel Dégremont Colleen A. Burge Daniel Mancilla Cortez Carolyn S. Friedman Gary B. Fleener Brett R. Dumbauld Chris Langdon |
author_facet |
Konstantin Divilov Blaine Schoolfield Benjamin Morga Lionel Dégremont Colleen A. Burge Daniel Mancilla Cortez Carolyn S. Friedman Gary B. Fleener Brett R. Dumbauld Chris Langdon |
author_sort |
Konstantin Divilov |
title |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_short |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_fullStr |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full_unstemmed |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_sort |
first evaluation of resistance to both a california oshv-1 variant and a french oshv-1 microvariant in pacific oysters |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12863-019-0791-3 https://doaj.org/article/e76e660be3194f75aa4d14dfde10670e |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
BMC Genetics, Vol 20, Iss 1, Pp 1-9 (2019) |
op_relation |
https://doi.org/10.1186/s12863-019-0791-3 https://doaj.org/toc/1471-2156 doi:10.1186/s12863-019-0791-3 1471-2156 https://doaj.org/article/e76e660be3194f75aa4d14dfde10670e |
op_doi |
https://doi.org/10.1186/s12863-019-0791-3 |
container_title |
BMC Genetics |
container_volume |
20 |
container_issue |
1 |
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1766394699600363520 |